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ScienceONTo elucidate the preventive effect of oriental medicine Gami-Ondamtang(GO) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a d...
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RISS 인기검색어
가미온담탕(加味溫膽湯)이 스트레스성 뇌신경전달물질(腦神經傳達物質) 변화(變化)에 미치는 영향(影響) = Effect of Gami-Ondamtang(GO) on brain neuronal transmitters in immobilized rats
한글로보기https://www.riss.kr/link?id=A100884006
- 저자
- 발행기관
- 학술지명
- 권호사항
-
발행연도
2001
-
작성언어
Korean
- 주제어
-
등재정보
KCI등재
-
자료형태
학술저널
-
수록면
114-121(8쪽)
- 제공처
-
0
상세조회 -
0
다운로드
부가정보
다국어 초록 (Multilingual Abstract)
To elucidate the preventive effect of oriental medicine Gami-Ondamtang(GO) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 8 organs were taken for measurement of organ weight. Brain was sectioned into 4 parts that are Frontal Cortex, Corpus Striatum, Hypothalamus and Hippocampus. Each part was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain without other significant physical change of rats. GO inhibited stress induced changes of neurotransmitter content in brain.
To elucidate the preventive effect of oriental medicine Gami-Ondamtang(GO) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 8 organs were taken for measurement of organ weight. Brain was sectioned into 4 parts that are Frontal Cortex, Corpus Striatum, Hypothalamus and Hippocampus. Each part was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain without other significant physical change of rats. GO inhibited stress induced changes of neurotransmitter content in brain.
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