Hydroxyapatite Derived from Marine Resources and their Potential Biomedical Applications

다국어 초록 (Multilingual Abstract)

Utilization of bone graft substitutes have increased due to the rising number of accidents, trauma, and aging population. Autograft is still considered as a gold standard for treating bone defects. However, limitations such as insufficient donor sites and secondary surgery, leads to the development of alternative grafts. Hydroxyapatite (HA) from natural resources gained much attention in recent years as a bone graft substitute due to its biocompatibility, excellent osteointegration, osteoconductive, and osteoinductive properties. In the current review, we have presented the isolation procedures of HA from marine fishbone and cuttlefish bone. Further, composite preparation using marine derived HA with other polymeric and ceramic materials were discussed, and cell-materials interaction were reviewed in detail towards bone tissue construction. Composite biomaterials with HA showed better cell proliferation, cell adhesion, increased gene expression (collagen, osteocalcin, osteopontin, bone sialoprotein, BMP- 2 etc.), and in vivo studies demonstrated significant bone formation with HA composite materials. Hence, composite biomaterials with hydroxyapatite will be potential candidates for artificial synthetic bone graft substitute.

참고문헌 (Reference)

1 V. Neuhaus, "rends in bone graft use in the United States" 37 : e783-e788, 2014

2 Ng, H. M, "X-ray diffraction analysis of scomberomorus guttatusderived hydroxyapatite and montmorillonite on polylactic acid biocomposite" 13 : 116-132, 2018

3 Kara, K, "Valorization of a good bioceramic from Moroccan waste fish bone by a heat treatment method" 7 : 1-7, 2019

4 Huang, Y. C, "Using hydroxyapatite from fish scales to prepare chitosan/gelatin/hydroxyapatite membrane:exploring potential for bone tissue engineering" 21 : 716-722, 2013

5 Oh, D. X, "Tunicatemimetic nanofibrous hydrogel adhesive with improved wet adhesion" 20 : 104-112, 2015

6 Prajatelistia, E, "Tunicate-inspired gallic acid/metal ion complex for instant and efficient treatment of dentin hypersensitivity" 5 : 919-927, 2016

7 Jahangir, M. U, "Thermal synthesis of hydroxyapatite from fish bones" 2121 : 140012-, 2018

8 Mansouri, K, "The role of cuttlebone and cuttlebone derived hydroxyapatite with platelet rich plasma on tibial bone defect healing in rabbit: An experimental study" 24 : 107-115, 2018

9 Zhu, Q, "The preparation and characterization of HA/βTCP biphasic ceramics from fish bones" 43 : 12213-12220, 2017

10 Weiner, S, "The material bone:Structure-mechanical function relations" 28 : 271-298, 1998

11 Liu, J., "The influence of pH and temperature on the morphology of hydroxyapatite synthesized by hydrothermal method" 29 : 629-633, 2003

12 Hartatiek, "The influence of chitosan on crystal size and microstructure of nano-hydroxyapatite from cuttlefish bone-chitosan composites" 13 : 30-35, 2019

13 Aminatun, "The effect of sintering process on the characteristics of hydroxyapatite from cuttlefish bone (Sepia sp.)" 4 : 1431-1442, 2013

14 Okumuş, Z, "The cuttlefish backbone:a new bone xenograft material?" 29 : 1177-1184, 2005

15 Lim, S, "The adhesive properties of coacervated recombinant hybrid mussel adhesive proteins" 31 : 3715-3722, 2010

16 Shavandi, A, "Synthesis of nano-hydroxyapatite (nHA) from waste mussel shells using a rapid microwave method" 149-150 : 607-616, 2015

17 Toriyama, M, "Synthesis of hydroxyapatite-based powders by mechano-chemical method and their sintering" 16 : 429-436, 1996

18 Li, X, "Synthesis of hydroxyapatite from cuttlefish bone via hydrothermal solid-state conversion" 6 : 775-779, 2016

19 Pamungkas, A, "Synthesis of hydroxyapatite from Tenggiri (Scomberomorus commersonii)fish bone: Findings on experiment and processes" 2092 : 020034-, 2019

20 Pal, A, "Synthesis of hydroxyapatite from Lates calcarifer fish bone for biomedical applications" 203 : 89-92, 2017

21 Pon-On, W, "Synthesis and investigations of mineral ions-loaded apatite from fish scale and PLA/chitosan composite for bone scaffolds" 221 : 143-146, 2018

22 Aksakal, B, "Synthesis and fabrication of novel cuttlefish (Sepia officinalis) backbone biografts for biomedical applications" 41 : 4531-4537, 2015

23 Sihotang, M. S, "Synthesis and characterization of pure natural hydroxyapatite from fishbone biowaste of coastal communities" 305 : 012072-, 2019

24 Neto, A. S, "Surface functionalization of cuttlefish bone-derived biphasic calcium phosphate scaffolds with polymeric coatings. Mater" 105 : 110014-, 2019

25 Ressler, A, "Strontium substituted biomimetic calcium phosphate system derived from cuttlefish bone" 108 : 1697-1709, 2020

26 Zeng, H, "Strong reversible Fe3+-mediated bridging between dopacontaining protein films in water" 107 : 12850-12853, 2010

27 SaradaPrasanna Mallick, "Strategies towards Orthopaedic Tissue Engineered Graft Generation: Current Scenario and Application" 한국생물공학회 24 (24): 854-869, 2019

28 Marcacci, M, "Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study" 13 : 947-955, 2007

29 Venkatesan, J, "Springer Handbook of Marine Biotechnology" Springer-Verlag 1195-1215, 2015

30 이상진, "Sintering Behavior and Biocompatibility of Calcium Phosphates Fabricated by Cuttlefish Bone and Phosphoric Acid" 한국조직공학과 재생의학회 7 (7): 556-560, 2010

31 Rocha, J. H. G, "Scaffolds for bone restoration from cuttlefish" 37 : 850-857, 2005

32 Quarto, R, "Repair of large bone defects with the use of autologous bone marrow stromal cells" 344 : 385-386, 2001

33 Ozawa, M, "Removal of aqueous lead by fish-bone waste hydroxyapatite powder" 40 : 1037-1038, 2005

34 Chattanathan, S. A, "Remediation of uranium-contaminated groundwater by sorption onto hydroxyapatite derived from catfish bones" 224 : 1429-, 2013

35 Michel, J, "Recent advances in hydroxyapatite scaffolds containing mesenchymal stem cells" 2015 : 305217-, 2015

36 Njinkoue, J. M, "Proximate composition, mineral content and fatty acid profile of two marine fishes from Cameroonian coast:Pseudotolithus typus (Bleeker, 1863) and Pseudotolithus elongatus (Bowdich, 1825)" 4 : 27-31, 2016

37 Nam, P. V, "Properties of hydroxyapatites prepared from different fish bones: A comparative study" 45 : 20141-20147, 2019

38 Sunil, B. R, "Producing hydroxyapatite from fish bones by heat treatment" 185 : 411-414, 2016

39 Awad, H. A, "Principles of Tissue Engineering" Academic Press 1733-1743, 2014

40 Ivankovic, H, "Preparation of highly porous hydroxyapatite from cuttlefish bone" 20 : 1039-1046, 2009

41 Lowe, B, "Preparation and characterization of chitosan-natural nano hydroxyapatite-fucoidan nanocomposites for bone tissue engineering" 93 : 1479-1487, 2016

42 Venkatesan, J, "Preparation and characterization of carbon nanotubegrafted-chitosan - Natural hydroxyapatite composite for bone tissue engineering" 83 : 569-577, 2011

43 Sarin, P, "Porous biphasic calcium phosphate scaffolds from cuttlefish bone" 94 : 2362-2370, 2011

44 Pallela, R, "Polymer assisted isolation of hydroxyapatite from Thunnus obesus bone" 37 : 3489-3497, 2011

45 Zhou, Y. Z, "Polydopamine-induced tooth remineralization" 4 : 6901-6910, 2012

46 Jiang, Y, "Pluripotency of mesenchymal stem cells derived from adult marrow" 418 : 41-49, 2002

47 Milovac, D, "PCL-coated hydroxyapatite scaffold derived from cuttlefish bone: in vitro cell culture studies" 42 : 264-272, 2014

48 Gendreau, "Overview of the clinical evidence for the use of NovaMin in providing relief from the pain of dentin hypersensitivity" 22 : 90-95, 2011

49 Hongmin, L, "Osteoinductive nanohydroxyapatite bone substitute prepared via in situ hydrothermal transformation of cuttlefish bone" 103 : 816-824, 2015

50 Clarke, S. A, "Osteogenic cell response to 3-D hydroxyapatite scaffolds developed via replication of natural marine sponges" 27 : 22-, 2016

51 Haberko, K, "Natural hydroxyapatite-its behaviour during heat treatment" 26 : 537-542, 2006

52 Gunduz, O, "Natural hydroxyapatite synthesis from fish bones: "Atlantic Bonito" (Sarda sarda)" 720 : 207-209, 2017

53 Terzioglu, P, "Natural calcium phosphates from fish bones and their potential biomedical applications" 91 : 899-911, 2018

54 Kong, L. B, "Nanosized hydroxyapatite powders derived from coprecipitation process" 37 : 1131-1134, 2002

55 Kongsri, S, "Nanocrystalline hydroxyapatite from fish scale waste: Preparation, characterization and application for selenium adsorption in aqueous solution" 215-216 : 522-532, 2013

56 Ryu, J, "Mussel-inspired polydopamine coating as a universal route to hydroxyapatite crystallization" 20 : 2132-2139, 2010

57 Ozawa, M, "Microstructural development of natural hydroxyapatite originated from fish-bone waste through heat treatment" 85 : 1315-1317, 2002

58 Siddiqi, S. A, "Mesenchymal stem cell (MSC) viability on PVA and PCL polymer coated hydroxyapatite scaffolds derived from cuttlefish" 6 : 32897-32904, 2016

59 Ferro, A. C, "Mechanochemical synthesis of hydroxyapatite using cuttlefish bone and chicken eggshell as calcium precursors" 97 : 124-140, 2019

60 Rho, J. Y, "Mechanical properties and the hierarchical structure of bone" 20 : 92-102, 1998

61 Ben-Nissan, B, "Marine-Derived Biomaterials for Tissue Engineering Applications" Springer 51-78, 2019

62 Venkatesan, J, "Isolation and characterization of nano-hydroxyapatite from salmon fish bone" 8 : 5426-5439, 2015

63 Lee, J. S, "In vivo study of chitosannatural nano hydroxyapatite scaffolds for bone tissue regeneration" 67 : 360-366, 2014

64 Mankani, M. H, "In vivo bone formation by human bone marrow stromal cells: Reconstruction of the mouse calvarium and mandible" 24 : 2140-2149, 2006

65 Aminatun, A, "In vivo approach on femur bone regeneration of white rat (Rattus norvegicus) with the use of hydroxyapatite from cuttlefish bone (Sepia spp.) as bone filler" 12 : 809-816, 2019

66 Asadollahzadeh, M, "In vitro apatite formation of calcium phosphate composite synthesized from fish bone" 16 : 1969-1978, 2019

67 Kim, B. S, "Improvement of the compressive strength of a cuttlefish bone-derived porous hydroxyapatite scaffold via polycaprolactone coating" 101 : 1302-1309, 2013

68 Piccirillo, C, "Hydroxyapatite-based materials of marine origin: a bioactivity and sintering study" 51 : 309-315, 2015

69 Komur, B, "Hydroxyapatite synthesis from fish bones: Atlantic salmon (Salmon Salar)" 131 : 400-402, 2017

70 Rocha, J. H. G, "Hydroxyapatite scaffolds hydrothermally grown from aragonitic cuttlefish bones" 15 : 5007-5011, 2005

71 El-Bassyouni, G. T, "Hydroxyapatite nanoparticles derived from mussel shells for in vitro cytotoxicity test and cell viability" 6 : e04085-, 2020

72 Pon-On, W, "Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material" 62 : 183-189, 2016

73 Granito, R. N, "Hydroxyapatite from fish for bone tissue engineering: A promising approach" 7 : 80-90, 2018

74 Jayachandran Venkatesan, "Hydroxyapatite from Cuttlefish Bone: Isolation, Characterizations, and Applications" 한국생물공학회 23 (23): 383-393, 2018

75 Ivankovic, H, "Hydroxyapatite formation from cuttlefish bones: kinetics" 21 : 2711-2722, 2010

76 Piccirillo, C, "Hydroxyapatite and chloroapatite derived from sardine by-products" 40 : 13231-13240, 2014

77 Tkalcec, E, "Hydrothermal synthesis and thermal evolution of carbonate-fluorhydroxyapatite scaffold from cuttlefish bones" 42 : 578-586, 2014

78 Kannan, S, "Fluorine-substituted hydroxyapatite scaffolds hydrothermally grown from aragonitic cuttlefish bones" 3 : 243-249, 2007

79 Admassu, W, "Feasibility of using natural fishbone apatite as a substitute for hydroxyapatite in remediating aqueous heavy metals" 69 : 187-196, 1999

80 Hadagalli, K, "Faster biomineralization and tailored mechanical properties of marine-resource-derived hydroxyapatite scaffolds with tunable interconnected porous architecture" 2 : 2171-2184, 2019

81 Cahyanto, A, "Fabrication of hydroxyapatite from fish bones waste using reflux method" 172 : 012006-, 2017

82 Park, J. Y, "Fabrication of blood coagulability calcium carbonate composite mimicking cuttlefish bone by layer-by-layer method" 6 : 2522-2525, 2014

83 qbal, F, "Extraction of hydroxyapatite from fish scales employing ionic liquids. US Patents 9,758,377B2"

84 Muhammad, N, "Extraction of biocompatible hydroxyapatite from fish scales using novel approach of ionic liquid pretreatment" 161 : 129-135, 2016

85 Zhang, L, "Extraction and characterization of HA/β-TCP biphasic calcium phosphate from marine fish" 236 : 680-682, 2019

86 Piccirillo, C, "Extraction and characterisation of apatite- and tricalcium phosphate-based materials from cod fish bones" 33 : 103-110, 2013

87 Kim, J. J, "Evaluation of biocompatibility of porous hydroxyapatite developed from edible cuttlefish bone" 361-363 : 155-158, 2008

88 Fathi, M. H, "Evaluation and characterization of nanostructure hydroxyapatite powder prepared by simple solgel method" 61 : 3978-3983, 2007

89 Kim, B. S, "Enhanced bone regeneration by silicon-substituted hydroxyapatite derived from cuttlefish bone" 28 : 49-56, 2017

90 Goto, T, "Effects of trace elements in fish bones on crystal characteristics of hydroxyapatite obtained by calcination" 40 : 10777-10785, 2014

91 114. Liu, Y, "Effects of cuttlefish bone-bone morphogenetic protein composite material on osteogenesis and revascularization of bone defect in rats" 29 : 548-553, 2013

92 Vano, M, "Effectiveness of nano-hydroxyapatite toothpaste in reducing dentin hypersensitivity: a double-blind randomized controlled trial" 45 : 703-711, 2014

93 In situ study. J. Dent, "Effect of toothpaste with nano-sized trimetaphosphate on dental caries" 43 : 806-813, 2015

94 Teixeira, M. A. C, "Effect of preparation and processing conditions on UV absorbing properties of hydroxyapatite-Fe2O3 sunscreen" 71 : 141-149, 2017

95 Demirel, M, "Effect of porosity on the structure, mechanical properties and cell viability of new bioceramics as potential bone graft substitutes" 20 : 11-22, 2018

96 Devitasari, S. P, "Effect of hydroxyapatite from waste of tilapia bone (Oreochromis niloticus) on the surface hardness of enamel" 1246 : 012009-, 2019

97 Browning, W. D, "Effect of a nano-hydroxyapatite paste on bleaching-related tooth sensitivity" 24 : 268-276, 2012

98 Prabakaran, K, "Development of hydroxyapatite from natural fish bone through heat treatment" 20 : 20-23, 2006

99 Asadollahzadeh, M, "Development of biological hydroxyapatite/chitosan composite for bone substitute cement" 2014

100 Vajrabhaya, L. O, "Cytotoxic and the proliferative effect of cuttlefish bone on MC3T3-E1 osteoblast cell line" 11 : 503-507, 2017

101 Neto, A. S, "Cuttlefish bone-derived biphasic calcium phosphate scaffolds coated with sol-gel derived bioactive glass" 12 : 2711-, 2019

102 Dogan, E, "Cuttlebone used as a bone xenograft in bone healing" 59 : 254-260, 2014

103 Chou, J, "Conversion of coral sand to calcium phosphate for biomedical applications" 43 : 44-48, 2007

104 Vecchio, K. S, "Conversion of bulk seashells to biocompatible hydroxyapatite for bone implants" 3 : 910-918, 2007

105 Reinares-Fisac, D, "Conversion of biogenic aragonite into hydroxyapatite scaffolds in boiling solutions" 19 : 110-116, 2017

106 Place, E. S, "Complexity in biomaterials for tissue engineering" 8 : 457-470, 2009

107 Kim, B. S, "Comparison of in vitro and in vivo bioactivity: cuttlefish-bone-derived hydroxyapatite and synthetic hydroxyapatite granules as a bone graft substitute" 9 : 025004-, 2014

108 Faksawat, K, "Comparison of characteristics of hydroxyapatite powders synthesized from cuttlefish bone via precipitation and ball milling techniques" 901 : 012083-, 2017

109 Yıldırım, Ö. S, "Comparative quantative analysis of sodium, magnesium, potassium and calcium in healthy cuttlefish backbone and non-pathological human elbow bone" 52 : 270-275, 2007

110 Mondal, S, "Comparative characterization of biogenic and chemical synthesized hydroxyapatite biomaterials for potential biomedical application" 228 : 344-356, 2019

111 Sukul, M, "Collagen-hydroxyapatite coated unprocessed cuttlefish bone as a bone substitute" 181 : 156-160, 2016

112 Wikanta, T, "Chitosan composite of crab shell and hydroxyapatite of tuna fish bone as biomaterials for guided tissue regeneration" 8 : 95-104, 2013

113 Shi, P, "Characterization of natural hydroxyapatite originated from fish bone and its biocompatibility with osteoblasts" 90 : 706-712, 2018

114 Akazawa, T, "Characterization of bio-absorbable and biomimetic apatite/collagen composite powders derived from fish bone and skin by the dissolution-precipitation method." 493-494 : 114-119, 2012

115 Kim, B. S., "Cellular attachment and osteoblast differentiation of mesenchymal stem cells on natural cuttlefish bone" 00 : 1673-1679, 2012

116 Giannoudis, P. V, "Bone substitutes: an update" 36 (36): S20-S27, 2005

117 Wang, W, "Bone grafts and biomaterials substitutes for bone defect repair: A review" 2 : 224-247, 2017

118 Pallela, R, "Biophysicochemical evaluation of chitosan-hydroxyapatitemarine sponge collagen composite for bone tissue engineering" 100 : 486-495, 2012

119 Abbasian, V, "Biomimetic nylon 6-baghdadite nanocomposite scaffold for bone tissue engineering" 109 : 110549-, 2020

120 Rogina, A, "Biomimetic design of bone substitutes based on cuttlefish bone-derived hydroxyapatite and biodegradable polymers" 107 : 197-204, 2019

121 Boutinguiza, M, "Biological hydroxyapatite obtained from fish bones" 32 : 478-486, 2012

122 Song, S. C. S, "Bioactivity evaluation of bio-hydroxyapatite derived from Spanish mackerel in composite scaffolds for bone tissue engineering" 2137 : 020015-, 2019

123 Cozza, N, "Bioactivity and mineralization of natural hydroxyapatite from cuttlefish bone and Bioglass® co-sintered bioceramics" 12 : e1131-e1142, 2018

124 Kim, B. S, "A polycaprolactone/cuttlefish bone-derived hydroxyapatite composite porous scaffold for bone tissue engineering" 102 : 943-951, 2014

125 Xu, G, "A cuttlebone-derived matrix substrate for hydrogen peroxide/glucose detection" 25 : 362-367, 2009

126 Venkatesan, J, "A comparative study of thermal calcination and an alkaline hydrolysis method in the isolation of hydroxyapatite from Thunnus obesus bone" 6 : 035003-, 2011