상부 위암에 대한 근위부 위절제술 및 위전절제술이 환자의 영양상태 및 삶의 질에 미치는 영향 평가 = Assessment of nutrition and quality of life after curative surgery in upper gastric cancer patients : comparison of total gastrectomy with uncut R-Y esophagojejunostomy and proximal gastrectomy

다국어 초록 (Multilingual Abstract)

Total gastrectomy has generally been performed for the treatment of upper third gastric cancer. However, the optimal extent of resection for the upper third gastric cancer of early stage is controversial until now.
In this article, I compared patient nutritional status and life of quality following both total gastrectomy with uncut R-Y esophagojejunostomy and proximal gastrectomy in order to identify to optimal method of the treatment of early stage upper third gastric cancer
In retrospective, randomized trial, I studied 50 patients with no evidence of recurrent disease following curative surgery for upper third gastric cancer. Among this group, 25 patients underwent total gastrectomy and 25 patients proximal gastrectomy of these, 8 total gastrectomy and 4 proximal gastrectomy patients were excluded from this study because of death, severe complication, refusal of interview etc. The nutritional status was assessed by mesuring body weight, serum albumin, serum total protein, serum hemoglobin. The gastrointestinal function and quality of life were assessed by Cuschieri grading, visick grading.
Proximal gastrectomy group demonstrated fewer weight loss(p=0.007) and better outcome by Visick grading (p=0.016) than total gastrectomy group. But there were no significant differences in the serum albumin (p=0.42), serum total protein (p=0.89), hemoglobin difference(p=0.89) and Cuschieri grading(p=0.064) between preoperative and postoperative data
Proximal gastrectomy led to a better quality of life than total gastrectomy in the study, as judged from the low weight loss and better Visick grading. In early stage gastric cancer, if no difference of survival rate, proximal gastrectomy seems to be superior to total gastrectomy.

목차 (Table of Contents)

• 目次
• Ⅰ. 서론 = 1
• Ⅱ. 연구 대상 및 방법 = 2
• Ⅲ. 결과 = 6
• Ⅳ. 고찰 = 10
• Ⅴ. 결론 = 13
• 참고문헌 = 14
• ABSTRACT = 17