여러 종류의 고양이 상피 항원에 대한 피부시험 결과 및 순수도 비교 = 여러 종류의 고양이 상피 항원에 대한 피부시험 결과 및 순수도 비교

다국어 초록 (Multilingual Abstract)

To evaluate the relatively high skin test reactivities to cat fur(CF) allergens compared to clinical history and RAST score, skin prick test (SPT) was done concurrently with three available commercial CF extracts(B, T, A Co)in Korea and the correlation of RAST score was evaluated. There were significant differences of SPT reactivity in CF extracts(B: 66.1%, T: 11.9%, A : 11.9%)but the results of T&A companies were comparable and correlated well with RAST rea- ctivity(T, A: 85.7%, B: 26.1%) and clinical symptoms(57.1%) and contact history(71.4%). RAST inhibition test with B, T and Korean CF extracts to D, farinae and D pteronyssinus revealed some inhibition by CF extracts(of B Co. DP 34% DF 2 1. %), but no inhibitions were noted by T and Korean CF extracts, With enzyme linked immunosorbent assay, Der p I was measurable(550ng/ml) and Der f I was also detected(6.5ng/ml) in B-CF extracts but none was found in T and Korean extracts The proportion of house dust mites was similar to the level of Der f I and Der p I in English house dust extrats. Contamination of B-cat fur extracts with house dust mites would be significant. So it is difficult to justity the use of such commercial CF extracts as diagnostic agents and further study on the allergen content must be done in other extracts, such as dog hair or mixed threshing dust which has high SPT positivity compared to clinical hstory