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      장내세균의 약제내성  :  제1보 대장균의 Nalidixic Acid 및 기타 항균제에 대한 내성 Resistance of Escherichia coli to naldixic acid and six other antibacterial agents = Resistance of Enterobacteriaceae to antibacterial drugs

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      https://www.riss.kr/link?id=A3181089

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      Nalidixic acid and six other drugs were studied for in vitro effectiveness against 200 strains of Escherichia coli isolated recently from heaIthy persons and bactericidal activity of ampicillin against one respective strain of Escherichia coli and SalmonelIa typhi isolated were also studied.
      The results obtained by the plate dilution method showed the following percentage of resistance: kanamycin, 2, 5%; streptomycin, 12. 0%; ampicillin, 13. 5%; tetracyclin, 15. 5%; chloramphenicoI, 17. 5%; colistin sulfate, 19. 5%. No strains were reaistant to nalidixic acid, clearly indicating that nalidixic acid is the most effective drug tested.
      Ampicillin, measured by test-tube diltion method, was highly bactericidal against Salmonella typhi at the concentration of 2. 5 mcg/ml and against Escherichia coIi at 5mcg/ml.
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      Nalidixic acid and six other drugs were studied for in vitro effectiveness against 200 strains of Escherichia coli isolated recently from heaIthy persons and bactericidal activity of ampicillin against one respective strain of Escherichia coli and Sal...

      Nalidixic acid and six other drugs were studied for in vitro effectiveness against 200 strains of Escherichia coli isolated recently from heaIthy persons and bactericidal activity of ampicillin against one respective strain of Escherichia coli and SalmonelIa typhi isolated were also studied.
      The results obtained by the plate dilution method showed the following percentage of resistance: kanamycin, 2, 5%; streptomycin, 12. 0%; ampicillin, 13. 5%; tetracyclin, 15. 5%; chloramphenicoI, 17. 5%; colistin sulfate, 19. 5%. No strains were reaistant to nalidixic acid, clearly indicating that nalidixic acid is the most effective drug tested.
      Ampicillin, measured by test-tube diltion method, was highly bactericidal against Salmonella typhi at the concentration of 2. 5 mcg/ml and against Escherichia coIi at 5mcg/ml.

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