임신 중 갑상선질환의 최신지견 = Thyroid Disease in Pregnancy

다국어 초록 (Multilingual Abstract)

It is the purpose of this paper to review the available evidence useful in determining the best course of therapy for patient with thyroid disease in pregnancy. The pregnancy is complicated occasionally by thyroid disease but the interest notes that the thyroid disorder is complicated by pregnancy. There is general agreement that normal pregnancy is associated with an increase in the meta- bolic rate, an increase in serum lipids, an increase in thyroid size, an increase in radiooidine uptake, an elevation in the citculating level of thyroxine, and an increase in the thyroxine-binding globulin(TBG)with a normal level of circulating free thyroxine. In normal pregnancy, an increase of binding globulin is relative to circulating thyroxin, and reciprocally T3 uptake by resin or red blood cells is low, this test will serve to differentiate normal pregnancy from pregnancy complicated by hyperthyroidism. However, it is not useful for the evaluation of possible hypothyroidism and pregnancy. The other thyroid conditions in pregnancy beside the hyperthyroidism and hypothyroidism are acute thyroiditis, thyroid carcinoma and nontoxic goiter. They are discussed in this review. Patient with hydatidiform mole may have an increase in thyroid function with radioiodine uptake of the thyroid, the studies of thyroid function in patient with hydatidiform mole and choriocarcinoma are interesting.