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    사회불안장애의 회피 증상과 심박변이도 반응성 = Heart Rate Variability Reactivity and Avoidance in Social Anxiety Disorder

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    https://www.riss.kr/link?id=A109348898

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    Objective : Reduced resting heart rate variability (HRV) is well-documented in anxiety and mood disorders; however, limited research exists on HRV reactivity during emotional processing. This study examined HRV reactivity to angry faces in social anxiety disorder (SAD) patients and its association with symptom severity.
    Methods : Twenty-six SAD patients and 35 controls participated. HRV was measured using the root mean square of successive differences (RMSSD). RMSSD reactivity was calculated by subtracting RMSSD during angry and neutral face processing from baseline RMSSD. Group differences in RMSSD reactivity and its relationship with social anxiety symptoms were analyzed.
    Results : SAD patients exhibited lower RMSSD reactivity compared to controls during both angry (t54.829= 3.03, p=0.004) and neutral face processing (t52.877=2.18, p=0.034). In the SAD group, RMSSD reactivity during angry face processing significantly explained variance in performance avoidance subscale scores of the Liebowitz Social Anxiety Scale (R2 =0.208, β=-0.456, F1,23=6.054, p=0.022).
    Conclusion : Reduced HRV reactivity in SAD may reflect impaired autonomic flexibility and difficulty responding to emotionally relevant stressors. Lower HRV reactivity is associated with greater symptom severity, specifically performance-related avoidance, highlighting HRV’s potential as a physiological marker for identifying specific symptoms in SAD. (Anxiety and Mood 2024;20(2):35-40)
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    Objective : Reduced resting heart rate variability (HRV) is well-documented in anxiety and mood disorders; however, limited research exists on HRV reactivity during emotional processing. This study examined HRV reactivity to angry faces in social anxi...

    Objective : Reduced resting heart rate variability (HRV) is well-documented in anxiety and mood disorders; however, limited research exists on HRV reactivity during emotional processing. This study examined HRV reactivity to angry faces in social anxiety disorder (SAD) patients and its association with symptom severity.
    Methods : Twenty-six SAD patients and 35 controls participated. HRV was measured using the root mean square of successive differences (RMSSD). RMSSD reactivity was calculated by subtracting RMSSD during angry and neutral face processing from baseline RMSSD. Group differences in RMSSD reactivity and its relationship with social anxiety symptoms were analyzed.
    Results : SAD patients exhibited lower RMSSD reactivity compared to controls during both angry (t54.829= 3.03, p=0.004) and neutral face processing (t52.877=2.18, p=0.034). In the SAD group, RMSSD reactivity during angry face processing significantly explained variance in performance avoidance subscale scores of the Liebowitz Social Anxiety Scale (R2 =0.208, β=-0.456, F1,23=6.054, p=0.022).
    Conclusion : Reduced HRV reactivity in SAD may reflect impaired autonomic flexibility and difficulty responding to emotionally relevant stressors. Lower HRV reactivity is associated with greater symptom severity, specifically performance-related avoidance, highlighting HRV’s potential as a physiological marker for identifying specific symptoms in SAD. (Anxiety and Mood 2024;20(2):35-40)

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    참고문헌 (Reference)

    1 Porges SW, "The polyvagal perspective" 74 : 116-143, 2007

    2 Draghici AE, "The physiological basis and measurement of heart rate variability in humans" 35 : 22-, 2016

    3 Hamilton M, "The assessment of anxiety states by rating" 32 : 50-55, 1959

    4 Sheehan DV, "The Anxiety Disease" Scribner 1983

    5 Hollenstein T, "Sympathetic and parasympathetic responses to social stress across adolescence" 54 : 207-214, 2012

    6 Cohen J, "Statistical power analysis for the behavioral sciences" routledge 2013

    7 Liebowitz MR, "Social phobia" 22 : 141-173, 1987

    8 Schneier F, "Social anxiety disorder" 49-67, 2015

    9 Leary MR, "Social anxiety" Guilford Press 1997

    10 Alvares GA, "Reduced heart rate variability in social anxiety disorder : associations with gender and symptom severity" 8 : e70468-, 2013

    1 Porges SW, "The polyvagal perspective" 74 : 116-143, 2007

    2 Draghici AE, "The physiological basis and measurement of heart rate variability in humans" 35 : 22-, 2016

    3 Hamilton M, "The assessment of anxiety states by rating" 32 : 50-55, 1959

    4 Sheehan DV, "The Anxiety Disease" Scribner 1983

    5 Hollenstein T, "Sympathetic and parasympathetic responses to social stress across adolescence" 54 : 207-214, 2012

    6 Cohen J, "Statistical power analysis for the behavioral sciences" routledge 2013

    7 Liebowitz MR, "Social phobia" 22 : 141-173, 1987

    8 Schneier F, "Social anxiety disorder" 49-67, 2015

    9 Leary MR, "Social anxiety" Guilford Press 1997

    10 Alvares GA, "Reduced heart rate variability in social anxiety disorder : associations with gender and symptom severity" 8 : e70468-, 2013

    11 Dannahy L, "Post-event processing in social anxiety" 45 : 1207-1219, 2007

    12 Nardi AE, "Panic disorder and obsessive compulsive disorder in a hyperventilation challenge test" 68 : 335-340, 2002

    13 Kim SY, "Neural evidence for persistent attentional bias to threats in patients with social anxiety disorder" 13 : 1327-1336, 2018

    14 Rabellino D, "Neural correlates of heart rate variability in PTSD during sub-and supraliminal processing of trauma-related cues" 38 : 4898-4907, 2017

    15 Mansell W, "Internal versus external attention in social anxiety : an investigation using a novel paradigm" 41 : 555-572, 2003

    16 Cheng YC, "Heart rate variability in patients with anxiety disorders : a systematic review and meta-analysis" 76 : 292-302, 2022

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    24 American Psychiatric Association D, "Diagnostic and statistical manual of mental disorders: DSM-5" American Psychiatric Association D 2013

    25 Martens E, "Depression and anxiety as predictors of heart rate variability after myocardial infarction" 38 : 375-383, 2008

    26 Ji L, "Comparison of heart rate variability between resting state and external-cuff-inflation-and-deflation state : a pilot study" 36 : 2135-2146, 2015

    27 Matthews KA, "Cardiovascular responses of adolescents during a naturally occurring stressor and their behavioral and psychophysiological predictors" 23 : 198-209, 1986

    28 Rottenberg J, "Cardiac vagal control in depression : a critical analysis" 74 : 200-211, 2007

    29 Manser P, "Can reactivity of heart rate variability be a potential biomarker and monitoring tool to promote healthy aging? A systematic review with metaanalyses" 12 : 686129-, 2021

    30 Thayer JF, "Beyond heart rate variability : vagal regulation of allostatic systems" 1088 : 361-372, 2006

    31 Hamilton JL, "Atypical reactivity of heart rate variability to stress and depression across development : systematic review of the literature and directions for future research" 50 : 67-79, 2016

    32 Chalmers JA, "Anxiety disorders are associated with reduced heart rate variability : a meta-analysis" 5 : 80-, 2014

    33 Shaffer F, "An overview of heart rate variability metrics and norms" 5 : 258-, 2017

    34 Beck AT, "An inventory for measuring depression" 4 : 561-571, 1961

    35 Turk CL, "An integrated cognitive-behavioral model of social anxiety" 2001

    36 Jung YH, "Altered amygdala resting-state functional connectivity and hemispheric asymmetry in patients with social anxiety disorder" 9 : 164-, 2018

    37 Makovac E, "Alterations in amygdala-prefrontal functional connectivity account for excessive worry and autonomic dysregulation in generalized anxiety disorder" 80 : 786-795, 2016

    38 Thayer JF, "A metaanalysis of heart rate variability and neuroimaging studies : implications for heart rate variability as a marker of stress and health" 36 : 747-756, 2012

    39 Rapee RM, "A cognitive-behavioral model of anxiety in social phobia" 35 : 741-756, 1997

    40 Leary MR, "A brief version of the Fear of Negative Evaluation Scale" 9 : 371-375, 1983

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