역 사정 환자의 성공적인 인공수정 = Successful Artificial Insemination following Retrograde Ejaculation Patient

국문 초록 (Abstract)

역 사정은 남성불임 원인의 하나인데, 이를 해결 하기 위해서는 사정 후 방광으로부터 정자를 회수하여 보조생식술을 시행함으로써 불임을 극복할 수 있다. 배우자의 뇨로부터 정자를 회수한 후 인공수정을 시도하여 많은 임신이 보고되고 있는데, 본원에서는 Clomiphene Citrate와 hMG를 사용하여 배란을 유도하고, 뇨와 함께 채취된 정액을 10% serum substitute supplement가 첨가된 modified Ham's F-10을 이용하여 뇨의 산성도와 삼투압 조절 후, 정자의 운동성을 유지하여 인공수정을 실시하였는데 성공적인 임신을 경험하여 문헌고찰과 함께 간략히 보고하는 바이다.

다국어 초록 (Multilingual Abstract)

Retrograde ejaculation is a condition that causes male infertility. Infertiltiy treatment is usually based on assisted reproductive technology with the use of sperms recovered from the bladder after ejaculation. Many pregnancies have been tried by artificial intrauterine insemination with the husband's sperm recovered from voided urine. In this case, ovulation was induced by clomiphene citrate and human menopausal gonadotropin, pH and osmorality of urine was controlled by modified Ham's F-10 contained 10% serum substitute supplement and immediately semen collection, to improve sperm motility. We had experienced a successful pregnancy case by above method, and reported with brief review of literature as well.

참고문헌 (Reference)

1 Jung BJ, "The study on successful therapy with electroejaculation and in vitro fertilization-embryo transfer" 11 : 1583-1591, 1992

2 Linsenmeyer T, "The effects of the electroejaculation procedure on sperm motility" 27 : 465-469, 1989

3 Saito K, "Successful pregnancy with sperm retrieved from the bladder after the introduction of a low-electrolyte solution for retrograde ejaculation" 69 : 1149-1151, 1998

4 Dahlberg B, "Sperm motility in fertile men and males in infertile units: in vitro test" 20 : 31-34, 1988

5 Leiva R, "Retrograde ejaculation: simpler treatment" 88 : e13-14, 2007

6 Cleine JH, "Retrograde ejaculation: evaluation of procedures related to assisted reproduction" 7 : 122-127, 1997

7 Cleine JH, "Retrograde ejaculation: can sperm retrieval be simpler and noninvasive?" 74 : 416-417, 2000

8 Sandler B, "Idiopathic retrograde ejaculation" 32 : 474-475, 1979

9 Makler A, "Factors affecting sperm motility. VII. Sperm viability as affected by change of pH and osmolarity of semen and urine specimens" 36 : 507-511, 1981

10 Aust TR, "Development and in vitro testing of a new method of urine preparation for retrograde ejaculation; the Liverpool solution" 89 : 885-891, 2008

11 Kapetanakis E, "Conception following insemination with a freeze-preserved retrograde ejaculate" 29 : 360-363, 1978

12 Jimenez C, "Birth after combination of cryopreservation of sperm recovered from urine and intracytoplasmic sperm injection in a case of complete retrograde ejaculation" 68 : 542-544, 1997

13 Hotchkiss RS, "Artificial insemination with semen recovered from the bladder" 6 : 37-42, 1954