생명 현상에 관한 가설 평가 과정에서 나타나는 두뇌 활성 양상 및 기능적 연결 네트워크 = Brain Activation Pattern and Functional Connectivity Network during Hypothesis-evaluating on Biological Phenomena

다국어 초록 (Multilingual Abstract)

The purpose of this study was to investigate brain activation pattern and functional connectivity network during hypothesis-evaluating on biological phenomena. Twenty six right-handed healthy science teachers volunteered to be in the present study. To investigate participants` brain activities (BOLD signals) during taking the tasks, 3.0T fMRI system with the block designed paradigm and the SPM2 software package were applied to the analysis of the acquired initial image data from the fMRI system. According to the analyzed results, left superior frontal gyrus, bilateral middle frontal gyrus, left inferior frontal gyrus, bilateral precuneus, right inferior parietal lobule, left middle occipital gyrus, right lingual gyrus, left cingulate gyrus, right culmen, bilateral declive, and right pyramis were significantly activated during participants` carrying-out hypothesis evaluation. The network model was consisting of eight nodes (ROIs) and its eight connections. These results suggested that the hypothesis evaluation process was not success just participants` make a choice of truth or falsehood. These results is presumable interpret scientific experimental design process from the cognitive neuroscience perspective. Also this study may be used as basic strategy for developing a teaching-learning program for scientific hypothesis-evaluating such as neural-network-based science education curriculum.

참고문헌 (Reference)

1 신동훈, "초등 과학 교육에서 두뇌 연구 방법의 고찰-fMRI 활용법을 중심으로-" 한국초등과학교육학회 26 (26): 49-62, 2007

2 박종원, "중학생들의 빛과그림자에 대한 증거평가" 13 (13): 135-박승재, 1993

3 권용주, "선언적 과학 지식의 생성 과정에 대한 과학철학적 연구: 귀납적, 귀추적, 연역적 과정을 중심으로" 한국과학교육학회 23 (23): 215-228, 2003

4 이준기, "생명현상에 관한 생물학자들의 경향성 지식 생성 과정에서 나타나는 두뇌 활성 양상 : fMRI 연구" 한국생물교육학회 36 (36): 178-188, 2008

5 이준기, "딱따구리 과제에서 초등예비 교사들의 가설 평가 지식에 대한 분석을 통한 가설 평가 능력 지수 산출식의 개발" 한국초등과학교육학회 27 (27): 49-59, 2008

6 이안나, "동물 행동학자의 연구 활동에서 나타나는 연구 단계, 사고 과정, 행동 양식 및 생성 지식에 관한 연구" 한국생물교육학회 35 (35): 361-373, 2007

7 유승식, "기능 자기 공명 영상 실험(실전 응용을 중심으로 한)" 서울:의학문화사. 2001

8 정진수, "과학자의 과학지식 생성 과정에 대한 심층 면담 연구" 한국과학교육학회 26 (26): 88-98, 2006

9 이혜정, "과학 현상에 대한 가설 평가의 사고 과정 모형 개발" 한국생물교육학회 36 (36): 478-489, 2008

10 Fangmeier, T., "fMRI Evidence for a three-stage model ofdeductive reasoning" 18 (18): 320-334, 2006

11 Henson,R, "What can functional neuroimagingtell the experimental psychologist?" 58A (58A): 193-233, 2005

12 Herwiga, U., "Verbal storage in a premotor-parietalnetwork: evidence from fMRI-guided magnetic stimulation" 20 (20): 1032-1041, 2003

13 Vlotz, G. C, "Variants of uncertainty in decision-making and theirneural correlates" 67 : 403-412, 2005

14 Friston, K. J, "Time-dependent changes in effective connectivitymeasured with PET" 1 : 69-79, 1993

15 Kuhn, D., "TheDevelopment of Scientific Thinking Skills" New York,NY: Academic Press 1988

16 Dawson, C., "The use of data in problemsolving: The ways, when and wherefores" 17 : 1-10, 1987

17 Horwitz,B, "The elusive concept of brain connectivity" 19 : 466-470, 2003

18 Kötter,R, "The anatomical basis of functional localization inthe cortex" 3 : 606-616, 2002

19 McPherson,G.R, "Teaching & learning thescientific method" 63 (63): 242-245, 2001

20 Amaro, E. Jr., "Study design infMRI: Basic principles" 60 : 220-232, 2006

21 Marrelec, R, "Regions, systems, and the brain: Hierarchicalmeasures of functional integration in fMRI" 12 : 484-496, 2008

22 Amodio, D. M., "Neurocognitive correlates of liberalism andconservatism" 10 : 1246-1247, 2007

23 Tsukiura, T., "Neuroanatomical discrimination between manipulatingand maintaining processes involved inverbal working memory; a functional MRI study" 11 : 13-21, 2001

24 Edin, F., "Mechanism for topdowncontrol of working memory capacity" 106 (106): 6802-6807, 2009

25 Buxton,R.B, "Introduction to Functional MagneticResonance Imaging: Principles and Techniques" Cambridge, UK: Cambridge University Press. 2002

26 Caveza, R., "Imaging cognitionⅡ: An empirical review of 275 PET and fMRI studies" 12 (12): 1-47, 2000

27 Koshino, H., "Functional connectivity in an fMRI working memorytask in high-functioning autism" 24 : 810-821, 2005

28 Huettel, S. A., "Functional Magnetic Resonance Imaging" Sinauer associate, 2004

29 Zhang, J. X., "Frontal activations associated with accessing andevaluating information in working memory: anfMRI study" 20 : 1531-1539, 2003

30 Goel, V., "Explaining modulationof reasoning by belief" 87 : B11-B22, 2003

31 Milner,G.A, "Effects of different brain lesionson card sorting" 9 : 90-100, 1963

32 Klahr, D, "Dual space searchduring scientific reasoning" 12 (12): 1-48, 1988

33 Goel, V., "Dissociating the rolesof right ventral lateral and dorsal lateral prefrontalcortex in generation and maintenance of hypothesisin set-shift problems" 15 (15): 1170-1177, 2005

34 Goel, V., "Differential involvementof left prefrontal cortex in inductive and deductivereasoning" 93 (93): B109-2, 2004

35 Tononi, G., "Complexityand coherency: intergrating information inthe brain" 2 (2): 474-484, 1998

36 Talairach, J, "Co-Planner StereotaxicAtlas of the Human Brain" ThiemeMedical publisher 1988

37 Frings, M., "Cerebellar involvement in verbgeneration: An fMRI study" 409 : 19-23, 2006

38 Ansari, D., "Bridge over troubled waters:education and cognitive neuroscience" 10 (10): 146-151, 2006

39 Rosenzweig, M. R., "Biological Psychology: An Introduction toBehavioral and Cognitive Neuroscience" SinauerAssociate 2005

40 Elliot, R, "Activation of differentanterior cingulate foci in association with hypothesistesting and response selectio" 8 : 17-29, 1998

41 Lee, L., "A reportof functional connectivity workshop, Dusseldorf2002" 19 : 457-465, 2003