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      조현병 환자의 유병기간에 따른 강박증상 = Obsessive-Compulsive Symptoms in Relation to Duration of Schizophrenia

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      https://www.riss.kr/link?id=A105447266

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      다국어 초록 (Multilingual Abstract)

      Objectives The aim of this study was to evaluate the psychopathological features such as depression and anxiety in schizophrenics with obsessive-compulsive symptoms (OCS) as well as the severity of OCS according to duration of schizophrenia. Methods We randomly selected sixty four inpatients with schizophrenia. We classified the patients into two groups (OCS group, non-OCS group) according to the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). Clinical and demographic features were evaluated. To assess OCS, Y-BOCS were performed. The Korean version of the Positive and Negative Syndrome Scale(K-PANSS), the Brief Psychiatric Rating Scale (BPRS), the Korean version of the Calgary Depression Scale for Schizophrenia (K-CDSS), the Beck Anxiety Inventory (BAI) and the Satisfaction With Life Scale (SWLS) were conducted. Independent t-test and chi-square test were conducted to compare the two groups. Pearson correlation analysis was performed to examine the relationship between the duration of schizophrenia and the Y-BOCS score. Results The Y-BOCS, K-CDSS, and BAI scores were higher in the OCS group. There was a significant correlation between the duration of schizophrenia and the Y-BOCS score. Conclusions Anxiety and depression symptoms were severe in the OCS group. In addition, the results of this study indicate that the longer duration of schizophrenia, the more severe the OCS. Therefore, the evaluation of OCS in schizophrenics should be accompanied by treatment intervention.
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      Objectives The aim of this study was to evaluate the psychopathological features such as depression and anxiety in schizophrenics with obsessive-compulsive symptoms (OCS) as well as the severity of OCS according to duration of schizophrenia. Methods W...

      Objectives The aim of this study was to evaluate the psychopathological features such as depression and anxiety in schizophrenics with obsessive-compulsive symptoms (OCS) as well as the severity of OCS according to duration of schizophrenia. Methods We randomly selected sixty four inpatients with schizophrenia. We classified the patients into two groups (OCS group, non-OCS group) according to the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). Clinical and demographic features were evaluated. To assess OCS, Y-BOCS were performed. The Korean version of the Positive and Negative Syndrome Scale(K-PANSS), the Brief Psychiatric Rating Scale (BPRS), the Korean version of the Calgary Depression Scale for Schizophrenia (K-CDSS), the Beck Anxiety Inventory (BAI) and the Satisfaction With Life Scale (SWLS) were conducted. Independent t-test and chi-square test were conducted to compare the two groups. Pearson correlation analysis was performed to examine the relationship between the duration of schizophrenia and the Y-BOCS score. Results The Y-BOCS, K-CDSS, and BAI scores were higher in the OCS group. There was a significant correlation between the duration of schizophrenia and the Y-BOCS score. Conclusions Anxiety and depression symptoms were severe in the OCS group. In addition, the results of this study indicate that the longer duration of schizophrenia, the more severe the OCS. Therefore, the evaluation of OCS in schizophrenics should be accompanied by treatment intervention.

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      참고문헌 (Reference)

      1 이중서, "한국판 양성 및 음성증후군 척도(Positive and Negative Syndrome Scale)의 신뢰도와 타당도" 대한신경정신의학회 40 (40): 1090-1105, 2001

      2 김용구, "한국어판 정신분열병의 캘거리 우울증 척도의 신뢰도 및 타당도 연구" 대한신경정신의학회 44 (44): 446-455, 2005

      3 문정윤, "안정화된 만성 조현병 환자에서 강박장애 증상이 삶의 질에 미치는 영향" 대한불안의학회 13 (13): 141-147, 2017

      4 김찬형, "강박증상이 동반된 정신분열병 환자의 임상적 특성" 대한정신약물학회 14 (14): 292-298, 2003

      5 Fenton WS, "The prognostic significance of obsessive-compulsive symptoms in schizophrenia" 143 : 437-441, 1986

      6 Kay SR, "The positive and negative syndrome scale (PANSS) for schizophrenia" 13 : 261-276, 1987

      7 Swets M, "The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates" 152 : 458-468, 2014

      8 Rosen I, "The clinical significance of obsessions in schizophrenia" 103 : 773-785, 1957

      9 Overall JE, "The brief psychiatric rating scale" 10 : 799-812, 1962

      10 Goodman WK, "The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability" 46 : 1006-1011, 1989

      1 이중서, "한국판 양성 및 음성증후군 척도(Positive and Negative Syndrome Scale)의 신뢰도와 타당도" 대한신경정신의학회 40 (40): 1090-1105, 2001

      2 김용구, "한국어판 정신분열병의 캘거리 우울증 척도의 신뢰도 및 타당도 연구" 대한신경정신의학회 44 (44): 446-455, 2005

      3 문정윤, "안정화된 만성 조현병 환자에서 강박장애 증상이 삶의 질에 미치는 영향" 대한불안의학회 13 (13): 141-147, 2017

      4 김찬형, "강박증상이 동반된 정신분열병 환자의 임상적 특성" 대한정신약물학회 14 (14): 292-298, 2003

      5 Fenton WS, "The prognostic significance of obsessive-compulsive symptoms in schizophrenia" 143 : 437-441, 1986

      6 Kay SR, "The positive and negative syndrome scale (PANSS) for schizophrenia" 13 : 261-276, 1987

      7 Swets M, "The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates" 152 : 458-468, 2014

      8 Rosen I, "The clinical significance of obsessions in schizophrenia" 103 : 773-785, 1957

      9 Overall JE, "The brief psychiatric rating scale" 10 : 799-812, 1962

      10 Goodman WK, "The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability" 46 : 1006-1011, 1989

      11 Hong JP, "The Survey of Mental Disorders in Korea" Sejong 275-278, 2017

      12 Diener E, "The Satisfaction With Life Scale" 49 : 71-75, 1985

      13 de Haan L, "The 5-year course of obsessive-compulsive symptoms and obsessive-compulsive disorder in first-episode schizophrenia and related disorders" 39 : 151-160, 2013

      14 Cunill R, "Relationships between obsessivecompulsive symptomatology and severity of psychosis in schizophrenia: a systematic review and meta-analysis" 70 : 70-82, 2009

      15 Soyata AZ, "Relationship of obsessive-compulsive symptoms to clinical variables and cognitive functions in individuals at ultra high risk for psychosis" 261 : 332-337, 2018

      16 Khullar A, "Quetiapine and obsessive-compulsive symptoms (OCS): case report and review of atypical antipsychoticinduced OCS" 26 : 55-59, 2001

      17 Cassin SE, "Quality of life in treatment-seeking patients with obsessive-compulsive disorder with and without major depressive disorder" 54 : 460-467, 2009

      18 Vivan Ade S, "Quality of life in adolescents with obsessive-compulsive disorder" 35 : 369-374, 2013

      19 Hou SY, "Quality of life and its correlates in patients with obsessive-compulsive disorder" 26 : 397-407, 2010

      20 Bobes J, "Quality of life and disability in patients with obsessive-compulsive disorder" 16 : 239-245, 2001

      21 이한경, "Psychometric Properties of the Beck Anxiety Inventory in the Community-dwelling Sample of Korean Adults" 한국임상심리학회 35 (35): 822-830, 2016

      22 Tibbo P, "Prevalence and relationship to delusions and hallucinations of anxiety disorders in schizophrenia" 17 : 65-72, 2003

      23 Sibrava NJ, "Prevalence and clinical characteristics of mental rituals in a longitudinal clinical sample of obsessive-compulsive disorder" 28 : 892-898, 2011

      24 Lysaker PH, "Patterns of obsessive-compulsive symptoms and social function in schizophrenia" 125 : 139-146, 2004

      25 de Haan L, "Obsessive-compulsive symptoms during treatment with olanzapine and risperidone: a prospective study of 113 patients with recent-onset schizophrenia or related disorders" 63 : 104-107, 2002

      26 de Haan L, "Obsessive-compulsive symptoms and positive, negative, and depressive symptoms in patients with recent-onset schizophrenic disorders" 50 : 519-524, 2005

      27 Lysaker PH, "Obsessive-compulsive and negative symptoms in schizophrenia: associations with coping preference and hope" 141 : 253-259, 2006

      28 Prasko J, "Obsessive compulsive disorder and dissociation - comparison with healthy controls" 154 : 179-183, 2010

      29 Lysaker PH, "Obsessive and compulsive symptoms in schizophrenia: clinical and neurocognitive correlates" 188 : 78-83, 2000

      30 Berman I, "Obsessions and compulsions as a distinct cluster of symptoms in schizophrenia: a neuropsychological study" 186 : 150-156, 1998

      31 Jo MH, "National Comparison to Life Satisfaction. 1st ed." Jipmoondang 1-23, 1998

      32 Hwang MY, "Management of schizophrenia with obsessive-compulsive disorder" 35 : 36-43, 2005

      33 Hosseini SH, "Frequency and severity of obsessive-compulsive symptoms/disorders, violence and suicidal in schizophrenic patients" 14 : 345-351, 2012

      34 Poyurovsky M, "Fluvoxamine treatment in clozapine-induced obsessive-compulsive symptoms in schizophrenic patients" 19 : 305-313, 1996

      35 Boyette L, "Factor structure of the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) in a large sample of patients with schizophrenia or related disorders and comorbid obsessive-compulsive symptoms" 186 : 409-413, 2011

      36 Pogarell O, "Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder" 54 : 1406-1413, 2003

      37 American Psychiatric Association, "Diagnostic and Statistical Manual of Mental Disorders"

      38 Mahendran R, "De novo emergence of obsessive-compulsive symptoms with atypical antipsychotics in Asian patients with schizophrenia or schizoaffective disorder: a retrospective, cross-sectional study" 68 : 542-545, 2007

      39 Englisch S, "Clozapine-induced obsessive-compulsive syndromes improve in combination with aripiprazole" 32 : 227-229, 2009

      40 Albert U, "Clinical predictors of health-related quality of life in obsessive-compulsive disorder" 51 : 193-200, 2010

      41 Hwang MY, "Clinical and neuropsychological profiles of obsessive-compulsive schizophrenia: a pilot study" 12 : 91-94, 2000

      42 Kim SW, "Associations of obsessive-compulsive symptoms with clinical and neurocognitive features in schizophrenia according to stage of illness" 226 : 368-375, 2015

      43 Stengel E, "A study of some clinical aspects of the relationship between obsessional neurosis and psychotic types" 91 : 166-187, 1945

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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.19 0.19 0.19
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.14 0.15 0.475 0
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