Usefulness of Fast Oscillation Electrooculography in Chronic Central Serous Chorioretinopathy

다국어 초록 (Multilingual Abstract)

Purpose: To confirm retinal pigment epithelium (RPE) function by using fast oscillation electrooculography (FO EOG) in patients with central serous chorioretinopathy (CSC) compared with normal controls.
Methods: We retrospectively reviewed 22 eyes of CSC patients (7 with the acute form and 15 with the chronic form) and 20 eyes of normal controls who underwent FO EOG. The FO was measured in four groups of subjects: acute CSC, chronic CSC, fellow eyes, and normal controls. Light trough (LT) voltage, dark-peak voltage, and peak-to-trough (PT) ratios were recorded. Central macular thickness was also measured using spectral domain-optical coherence tomography. The CSC group and the normal group were compared.
Results: In CSC eyes, the LT voltage decreased and the PT ratio increased significantly compared to the normal eyes (p = 0.013 and 0.024, respectively). We further divided the CSC group into acute (n = 7) and chronic (n = 15). In the chronic CSC group, the LT voltage decreased and the PT ratio increased statistically significantly compared to the normal eyes (p = 0.028 and 0.028, respectively).
Conclusions: In CSC eyes, RPE function is altered as it progresses to chronic, and this functional change can be confirmed through the amplitude of the LT revealed by FO ERG.

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