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    토종닭과 실용계에서 TYR 및 MC1R 유전자의 변이 분석 = Investigation of TYR and MC1R polymorphisms in Korean native chickens and the commercial chickens

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    https://www.riss.kr/link?id=A105056257

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    다국어 초록 (Multilingual Abstract) kakao i 다국어 번역

    The commercial Korean native chickens (WR_CC) was developed by crossing a few native chicken breeds in Korea. In order to investigate the breed identification markers, SNPs from TYR gene and MC1R gene, which are associated with skin and feather colors respectively, were initially identified. In case of 3 identified SNPs in the TYR gene, yellow shank color was identified in Loss, Harvard, AA, RIR and CC, which have the fixed SNPs in most of the animals. On the other hand, SNP variations were observed in KNC_RB, C_B, WR_CC and HH_CC, which have the black, yellow and mixed color with black and yellow shank colors. Also, the investigation of 3 SNPs in the MC1R gene indicated that there were associations between shank and feather colors in RIR, SF, KNC_B, C_B and RIR. However, these results are not consistent among breeds. These SNP type inconsistencies within breeds suggested that the selection was performed based on the phenotypes, which is not include the genotype information. Thus, selection based on genetic information is required in the future.
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    The commercial Korean native chickens (WR_CC) was developed by crossing a few native chicken breeds in Korea. In order to investigate the breed identification markers, SNPs from TYR gene and MC1R gene, which are associated with skin and feather colors...

    The commercial Korean native chickens (WR_CC) was developed by crossing a few native chicken breeds in Korea. In order to investigate the breed identification markers, SNPs from TYR gene and MC1R gene, which are associated with skin and feather colors respectively, were initially identified. In case of 3 identified SNPs in the TYR gene, yellow shank color was identified in Loss, Harvard, AA, RIR and CC, which have the fixed SNPs in most of the animals. On the other hand, SNP variations were observed in KNC_RB, C_B, WR_CC and HH_CC, which have the black, yellow and mixed color with black and yellow shank colors. Also, the investigation of 3 SNPs in the MC1R gene indicated that there were associations between shank and feather colors in RIR, SF, KNC_B, C_B and RIR. However, these results are not consistent among breeds. These SNP type inconsistencies within breeds suggested that the selection was performed based on the phenotypes, which is not include the genotype information. Thus, selection based on genetic information is required in the future.

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    참고문헌 (Reference)

    1 Pielberg G, "Unexpectedly high allelic diversity at the KIT locus causing dominant white color in the domestic pig" 160 : 305-311, 2002

    2 Klungland H, "The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination" 6 (6): 636-639, 1995

    3 Kefala G, "RT-PCR for tyrosinase expression as a molecular marker in malignant melanoma" 7 (7): 325-330,

    4 Robbins LS, "Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function" 72 (72): 827-834, 1993

    5 Denovan-Wright EM, "Nucleotide sequence of transferrin cDNAs and tissue-specific of the transferrin gene in Atlantic cod (Gadus morhua)" 113 (113): 269-273, 1996

    6 Kijas JMH, "Melanocortin receptor 1(MC1R) mutations and coat color in pigs" 150 : 1177-1185, 1998

    7 Kerje S, "Melanocortin 1-receptor (MC1R) mutations are associated with plumage colour in chicken" 34 (34): 241-248, 2003

    8 Newton JM, "Melanocortin 1 receptor variation in the domestic dog" 11 (11): 24-30, 2000

    9 Sato S, "Mapping of the recessive white locus and analysis of the tyrosinase gene in chickens" 86 (86): 2126-2133, 2007

    10 Mochii M, "Isolation and characterization of a chicken tyrosinase cDNA" 5 (5): 162-167, 1992

    1 Pielberg G, "Unexpectedly high allelic diversity at the KIT locus causing dominant white color in the domestic pig" 160 : 305-311, 2002

    2 Klungland H, "The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination" 6 (6): 636-639, 1995

    3 Kefala G, "RT-PCR for tyrosinase expression as a molecular marker in malignant melanoma" 7 (7): 325-330,

    4 Robbins LS, "Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function" 72 (72): 827-834, 1993

    5 Denovan-Wright EM, "Nucleotide sequence of transferrin cDNAs and tissue-specific of the transferrin gene in Atlantic cod (Gadus morhua)" 113 (113): 269-273, 1996

    6 Kijas JMH, "Melanocortin receptor 1(MC1R) mutations and coat color in pigs" 150 : 1177-1185, 1998

    7 Kerje S, "Melanocortin 1-receptor (MC1R) mutations are associated with plumage colour in chicken" 34 (34): 241-248, 2003

    8 Newton JM, "Melanocortin 1 receptor variation in the domestic dog" 11 (11): 24-30, 2000

    9 Sato S, "Mapping of the recessive white locus and analysis of the tyrosinase gene in chickens" 86 (86): 2126-2133, 2007

    10 Mochii M, "Isolation and characterization of a chicken tyrosinase cDNA" 5 (5): 162-167, 1992

    11 Chan PA, "Interpreting missense variants: comparing computational methods in human disease genes CDKN2A, MLH1, MSH2, MECP2, and tyrosinase (TYR)" 28 (28): 683-693, 2007

    12 Evert RE, "Identification of a premature stop codon in the melanocyte- stimulating hormone receptor gene(MC1R) in labrador and golden retrievers with yellow coat color" 31 : 194-199, 2000

    13 Jackson IJ, "Genetics and molecular biology of mouse pigmentation" 7 (7): 73-80, 1994

    14 Zhang JQ, "Flesh color association with polymorphism of the tyrosinase gene in different Chinese chicken breeds" 37 (37): 165-169, 2010

    15 Sazanov A, "Evolutionarily conserved telomeric location of BBC1 and MC1R on a microchromosome questions the identity of MC1R and a pigmentation locus on chromosome 1 in chicken" 6 (6): 651-654, 1998

    16 Chang CM, "Complete association between a retroviral insertion in the tyrosinase gene and the recessive white mutation in chickens" 7 (7): 19-, 2006

    17 Lerner AB, "Biochemistry of melanin formation" 30 (30): 91-126, 1950

    18 Tobita-Teramoto T, "Autosomal albino chicken mutation (ca/ca) deletes hexanucleotide (-delta GACTGG817) at a copper-binding site of the tyrosinase gene" 79 (79): 46-50, 2000

    19 Takeuchi S, "A possible involvement of melanocortin 1-receptor in regulating feather color pigmentation in the chicken" 1308 (1308): 164-168, 1996

    20 Vage DI, "A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes" 15 (15): 311-315, 1997

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    학술지 이력

    학술지 이력
    연월일 이력구분 이력상세 등재구분
    2026 평가 재인증평가 신청대상 (재인증)
    2020-01-01 등재 등재학술지 유지 (재인증) KCI등재
    2017-01-01 등재 등재학술지 선정 (계속평가) KCI등재
    2016-03-31 학술지명변경 한글명 : 농업과학연구 -> Korean Journal of Agricultural Science
    외국어명 : JOURNAL OF AGRICULTURAL SCIENCE -> Korean Journal of Agricultural Science
    KCI등재후보
    2015-01-01 등재 등재후보학술지 선정 (신규평가) KCI등재후보
    2013-04-01 등재 등재후보 탈락 (기타)
    2011-01-01 등재 등재후보 1차 FAIL (등재후보1차) KCI등재후보
    2009-01-01 등재 등재후보학술지 선정 (신규평가) KCI등재후보
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    학술지 인용정보

    학술지 인용정보
    기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
    2016 0.28 0.28 0
    KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
    0 0 0 0.1
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