Acetamide was prepared directly from acetic acid and ammonia using silica gel as a catalyst. Ammonium salt was decomposed into acetamide and water spontaneously by dehydration catalyst at 170-l90℃. High purity acetamide was obtained in one-step reac...
Acetamide was prepared directly from acetic acid and ammonia using silica gel as a catalyst. Ammonium salt was decomposed into acetamide and water spontaneously by dehydration catalyst at 170-l90℃. High purity acetamide was obtained in one-step reaction. The process was simple and no further purification was necessary. This synthetic method was applied in the mass production industrially without any further modification.