Cloning, characterization, and expression of the CIP2 gene induced under cadmium stress in Candida sp. = 중금속 stress에 의하여 유도발현되는 candida의 CIP1과 CIP2 유전자의 기능 및 발현조절

다국어 초록 (Multilingual Abstract)

We isolated, sequenced, and expressed a cadmium-induced gene, CIP2, that specifically hybridizes to a mRNA of approximately 950 nucleotides The CIP2 mRNA was barely present in normal Candida cells, but accumulated at higher levels in cadmium-treated cells Other heavy metals such as copper, mercury, lead, and manganese had no effect on the expression of the CIP2 gene CIP2 contains an open reading frame encoding a protein of 203 amino acids This gene was also activated by an oxidant, diamide Our results suggest that CIP2 may play a crucial role in the specific cellular response to oxidative stress evolved by the cadmium treatment ⓒ 1998 Federation of European Microbiological Societies Phblished by Elsevier Science B V

목차 (Table of Contents)

• 1.Abstract
• 2.Introduction
• 3.Materials and methods
• 4.Results and discussion
• 5.Acknowledgments
• 6.References
• T Vector for Direct Selection using Green Fluorescent Protein
• References