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      SCOPUS KCI등재

      다수의 경부림프절과 연부조직을 동시에 침범한 두피의 랑게르한스세포육종 1예 = Langerhans Cell Sarcoma of the Scalp with Concomitant Multiple Cervical Lymph Node and Adjacent Soft Tissue Involvement: A Case Report

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      https://www.riss.kr/link?id=A106456352

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      다국어 초록 (Multilingual Abstract)

      Currently, the World Health Organization classifies Langerhans cell tumors into Langerhans cell histiocytosis and Langerhans cell sarcoma (LCS). LCS is a neoplastic proliferation of Langerhans cells showing malignant cytological features and aggressive clinical behavior with grave prognosis. Only a few cases have been reported in the available literature; therefore, to date, no definitive treatment has been established. A 64-year-old woman presented with a 1-year history of an asymptomatic, slow-growing erythematous nodule measuring 0.7 cm on her scalp. The patient also reported a 3-month history of a painful swelling on the right side of her neck. Histopathological examination of a scalp biopsy specimen revealed sheets of atypical cells with hyperchromatic nucleoli and clear cytoplasm. Immunohistochemical studies revealed malignant cells positive for CD1a, CD31, CD68, and S-100 expression. Additionally, positron emission tomography-computed tomography and fine-needle aspiration revealed LCS of the cervical lymph nodes and surrounding soft tissue. We recommended surgical excision and adjunctive chemotherapy; however, the patient refused treatment and died of the disease 28 months later. (Korean J Dermatol 2019;57(9):538∼543)
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      Currently, the World Health Organization classifies Langerhans cell tumors into Langerhans cell histiocytosis and Langerhans cell sarcoma (LCS). LCS is a neoplastic proliferation of Langerhans cells showing malignant cytological features and aggressiv...

      Currently, the World Health Organization classifies Langerhans cell tumors into Langerhans cell histiocytosis and Langerhans cell sarcoma (LCS). LCS is a neoplastic proliferation of Langerhans cells showing malignant cytological features and aggressive clinical behavior with grave prognosis. Only a few cases have been reported in the available literature; therefore, to date, no definitive treatment has been established. A 64-year-old woman presented with a 1-year history of an asymptomatic, slow-growing erythematous nodule measuring 0.7 cm on her scalp. The patient also reported a 3-month history of a painful swelling on the right side of her neck. Histopathological examination of a scalp biopsy specimen revealed sheets of atypical cells with hyperchromatic nucleoli and clear cytoplasm. Immunohistochemical studies revealed malignant cells positive for CD1a, CD31, CD68, and S-100 expression. Additionally, positron emission tomography-computed tomography and fine-needle aspiration revealed LCS of the cervical lymph nodes and surrounding soft tissue. We recommended surgical excision and adjunctive chemotherapy; however, the patient refused treatment and died of the disease 28 months later. (Korean J Dermatol 2019;57(9):538∼543)

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      참고문헌 (Reference)

      1 Jaffe E, "World Health Organization Classification: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues" IARC Press 273-283, 2001

      2 Pileri SA, "Tumours of histiocytes and accessory dendritic cells : an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases" 41 : 1-29, 2002

      3 Delabie J, "True histiocytic neoplasm of Langerhans’ cell type" 163 : 217-223, 2003

      4 Slone SP, "Sinus histiocytosis with massive lymphadenopathy and Langerhans cell histiocytosis express the cellular adhesion molecule CD31" 127 : 341-344, 2003

      5 Jülg BD, "Pulmonary manifestation of a Langerhans cell sarcoma : a case report and review of the literature" 448 : 369-374, 2006

      6 Sagransky MJ, "Primary cutaneous langerhans cell sarcoma : a report of four cases and review of the literature" 35 : 196-204, 2013

      7 Deng A, "Primary cutaneous Langerhans cell sarcoma without Birbeck granules : indeterminate cell sarcoma" 35 : 849-854, 2008

      8 Ben-Ezra J, "Malignant histiocytosis X : a distinct clinicopathologic entity" 68 : 1050-1060, 1991

      9 Tani M, "Malignant Langerhans cell tumour" 126 : 398-403, 1992

      10 Lieberman PH, "Langerhans cell(eosinophilic)granulomatosis : a clinicopathologic study encompassing 50 years" 20 : 519-552, 1996

      1 Jaffe E, "World Health Organization Classification: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues" IARC Press 273-283, 2001

      2 Pileri SA, "Tumours of histiocytes and accessory dendritic cells : an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases" 41 : 1-29, 2002

      3 Delabie J, "True histiocytic neoplasm of Langerhans’ cell type" 163 : 217-223, 2003

      4 Slone SP, "Sinus histiocytosis with massive lymphadenopathy and Langerhans cell histiocytosis express the cellular adhesion molecule CD31" 127 : 341-344, 2003

      5 Jülg BD, "Pulmonary manifestation of a Langerhans cell sarcoma : a case report and review of the literature" 448 : 369-374, 2006

      6 Sagransky MJ, "Primary cutaneous langerhans cell sarcoma : a report of four cases and review of the literature" 35 : 196-204, 2013

      7 Deng A, "Primary cutaneous Langerhans cell sarcoma without Birbeck granules : indeterminate cell sarcoma" 35 : 849-854, 2008

      8 Ben-Ezra J, "Malignant histiocytosis X : a distinct clinicopathologic entity" 68 : 1050-1060, 1991

      9 Tani M, "Malignant Langerhans cell tumour" 126 : 398-403, 1992

      10 Lieberman PH, "Langerhans cell(eosinophilic)granulomatosis : a clinicopathologic study encompassing 50 years" 20 : 519-552, 1996

      11 Ferringer T, "Langerhans cell sarcoma" 28 : 36-39, 2006

      12 Henry RJ, "Langerhans cell histiocytosis : case reports and literature review" 18 : 11-16, 1996

      13 강동욱, "Langerhans Cell Sarcoma Arising in a Lymph Node - A Case Report and Review of the Literature -" 대한병리학회 45 (45): 101-105, 2011

      14 이종실, "Langerhans Cell Sarcoma Arising from Langerhans Cell Histiocytosis: A Case Report" 대한의학회 21 (21): 577-580, 2006

      15 Lauritzen AF, "Histiocytic sarcomas" 18 : 73-80, 1995

      16 López-Ferrer P, "Fine needle aspiration cytology of Langerhans cell sarcoma" 19 : 59-61, 2008

      17 Zhao G, "Clinical and pathological features of Langerhans cell sarcoma : a case report of Langerhans cell sarcoma involving gall bladder and perineal lymph nodes" 19 : 1-7, 2008

      18 Kawase T, "CD56/NCAM-positive Langerhans cell sarcoma : a clinicopathologic study of 4 cases" 81 : 323-329, 2005

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-06-29 학술지명변경 외국어명 : 미등록 -> Korean Journal of Dermatology KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.11 0.11 0.13
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.13 0.14 0.254 0.01
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