한국의 두 지역사회에서 섬유근통 증후군과 만성 광범위 통증의 유병률과 위험요인 = Prevalence and Risk Factors of Fibromyalgia Syndrome and Chronic Widespread Pain in Two Communities in Korea -First Report in Korean

다국어 초록 (Multilingual Abstract)

Objective: To estimate the prevalence and risk factors of fibromyalgia syndrome (FMS) and chronic widespread pain (CWP) in Korean. Methods: Those who participated chronic pain field study in Uljin and Pohang, Kyongsang-buk-do in 2004 were evaluated for the prevalence of FMS and CWP. Diagnosis of FMS and CWP were made using American College of Rheumatology criteria. All 1,028 were interviewed based on a detailed questionnaire and 144 CWP patients were examined for tender points. Results: Among the 1,028 participants (mean age±SD, 63.3±12.7 years), 676 participants were female (mean age±SD, 62.1±13.5 years) and 352 participants were male (mean age±SD, 65.7±10.5 years). There were 23 cases of FMS (2.2%), which consisted of 21 female cases and 2 cases of male. Prevalence of FMS was significantly higher in female compared to male (3.1% vs 0.6%, p＜0.01). Prevalence of FMS showed increasing trend in the ascending order of age in decade (p＜0.001). CWP was detected in 144 cases (14.0%), which consisted of 130 female cases and 14 cases of male. Prevalence of CWP was also significantly higher in female compared to male (19.2% vs 4.0%, p＜0.001). Prevalence of CWP also showed increasing trend in the ascending order of age in decade (p＜0.001). Except for age and sex, hating vegetables is an associated factor for the development of FMS in CWP [OR 18.7 (95% CI 2.4, 145.3)] and diabetes is a risk factor for the development of FMS in normal population [OR 3.7 (95% CI 1.1, 11.9)] on multivariate analyses. Conclusion: The prevalence of FMS and CWP were 2.2% and 14.0% in Korean, respectively. The prevalence of FMS and CWP were significantly higher in female and aged individuals. Aging, female sex, hating vegetables and diabetes are prognostic factors for the development of FMS.

참고문헌 (Reference)

1 "Widespread pain:is an improved classification possible" 23 : 1628-1632, 1996

2 "The prevalence of pain in a general population:the results of a postal survey in a county of Sweden" 37 : 215-22, 1989

3 "The prevalence of pain complaints in a general population in Israel and its implications for utilization of health services" 27 : 1521-1525, 2000

4 "The prevalence of chronic widespread pain in the general population" 20 : 710-3, 1993

5 "The prevalence and characteristics of fibromyalgia in the general population" 38 : 19-28, 1995

6 "The prevalence and associated features of chronic widespread pain in the community using the 'Manchester' definition of chronic widespread pain" 38 : 275-279, 1999

7 "The effect of maximal exercise on temporal summation of second pain(windup)in patients with fibromyalgia syndrome" 2 : 334-344, 2001

8 "The London Fibromyalgia Epidemiology Study:the prevalence of fibromyalgia syndrome in London,Ontario" 26 : 1570-1576, 1999

9 "The American College of Rheumatology criteria for the classification of fibromyalgia:report of the multicenter criteria committee" 33 : 160-72, 1990

10 "Sociodemographic characteristics,risk factors and reproductive history in subjects with fibromyalgia results of a population- based case-control study" 62 : 46-59, 2003

11 "Risk factors for persistent chronic widespread pain:a community-based study" 40 : 95-101, 2001

12 "Prognostic factors for the development of fibromyalgia in women with self-reported musculoskeletal pain.A prospective study" 26 : 2458-2467, 1999

13 "Fibromyalgia syndrome improved using a mostly raw vegetarian diet:an observational study" 1 : 2001

14 "Fibromyalgia syndrome" 257 : 2782-7, 1987

15 "Fibromyalgia in diabetes mellitus" 23 : 171-173, 2003

16 "Fibromyalgia" 15 : 1-18, 1989

17 "Exercise for patients with fibromyalgia:risks versus benefits" 3 : 135-140, 2001

18 "Epidemiology of musculoskeletal disorders(complaints)and related disability in Canada" 12 : 1169-73, 1985

19 "Dietary glutamate will not affect pain in fibro-myalgia" 31 : 785-787, 2004

20 "Comorbidity and physician use in fibromyalgia" 135 : 76-81, 2005

21 "Classification,epidemiology and natural history of fibromyalgia" 5 : 320-329, 2001

22 "Chronic widespread pain in the community:the influence of psychological symptoms and mental disorder on healthcare seeking behavior" 26 : 413-419, 1999

23 "Chronic pain in a geographically defined general population:studies of differences in age,gender social class,and pain localization" 9 : 174-82, 1993

24 "Aspects of fibromyalgia in the general population:sex,pain threshold,and fibromyalgia symptoms" 22 : 151-156, 1995