반복 경두개자기자극술의 우울증 치료효과 및 최신동향에 대한 고찰 = Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation for Treatment of Depression and Latest Trends in TMS Techniques

다국어 초록 (Multilingual Abstract)

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique which can change cortical excitability in targeted area by producing magnetic field pulses with an electromagnetic coil. rTMS treatment has been used to treat various neuropsychiatric disorders including depression. In this review, we evaluate the literature on rTMS for depression by assessing its efficacy on different subtypes of depression and different technical parameters. In particular, we focus on the results of randomized clinical trials and meta-analyses for depression after the US Food and Drug Administration approval in 2008, which acknowledged its efficacy and acceptability. We also review the new forms of rTMS therapy including deep TMS, theta-burst stimulation, and magnetic seizure therapy (MST) that have been under recent investigation. High frequency rTMS over left dorsolateral prefrontal cortex (DLPFC), low frequency rTMS over right DLPFC, or bilateral rTMS is shown to be effective and acceptable in treatment for patients with non-psychotic, unipolar depression either as monotherapy or adjuvant. Deep TMS, theta-burst stimulation and MST are promising new TMS techniques which warrant further research.

참고문헌 (Reference)

1 Ciobanu C, "rTMS for pharmacoresistant major depression in the clinical setting of a psychiatric hospital: effectiveness and effects of age" 150 : 677-681, 2013

2 Pallanti S, "rTMS age-dependent response in treatment-resistant depressed subjects: a mini-review" 17 : 24-30, 2012

3 Peterson K, "VA evidence-based synthesis program evidence briefs" Department of Veterans Affairs 2011

4 Mathew SJ, "Treatment-resistant depression: recent developments and future directions" 25 : 989-992, 2008

5 Plewnia C, "Treatment of major depression with bilateral theta burst stimulation:a randomized controlled pilot trial" 156 : 219-223, 2014

6 Freitas C, "Treatment of auditory verbal hallucinations with transcranial magnetic stimulation in a patient with psychotic major depression: one-year follow-up" 18 : 57-65, 2012

7 Diego F Tavares, "Treatment of Bipolar Depression with Deep TMS: Results from a Double-Blind, Randomized, Parallel Group, Sham-Controlled Clinical Trial" Springer Nature 42 (42): 2593-2601, 2017

8 George MS, "Transcranial magnetic stimulation:applications in neuropsychiatry" 56 : 300-311, 1999

9 Poleszczyk A, "Transcranial magnetic stimulation in treatment of various psychiatric disorders-review of the most prominent studies and the latest news" 49 : 779-789, 2015

10 Herwig U, "Transcranial magnetic stimulation in therapy studies: examination of the reliability of “standard” coil positioning by neuronavigation" 50 : 58-61, 2001

11 Gershon AA, "Transcranial magnetic stimulation in the treatment of depression" 160 : 835-845, 2003

12 Dolberg OT, "Transcranial magnetic stimulation in patients with bipolar depression: a double blind, controlled study" 4 (4): 94-95, 2002

13 Hizli Sayar G, "Transcranial magnetic stimulation for treating depression in elderly patients" 9 : 501-504, 2013

14 Janicak PG, "Transcranial magnetic stimulation for the treatment of major depression" 11 : 1549-1560, 2015

15 Sabesan P, "Transcranial magnetic stimulation for geriatric depression:Promises and pitfalls" 5 : 170-181, 2015

16 McNamara B, "Transcranial magnetic stimulation for depression and other psychiatric disorders" 31 : 1141-1146, 2001

17 Roth Y, "Three-dimensional distribution of the electric field induced in the brain by transcranial magnetic stimulation using figure-8 and deep H-coils" 24 : 31-38, 2007

18 Chung SW, "Theta-burst stimulation: a new form of TMS treatment for depression?" 32 : 182-192, 2015

19 Herwig U, "The navigation of transcranial magnetic stimulation" 108 : 123-131, 2001

20 Schrijvers DL, "The impact of highfrequency repetitive transcranial magnetic stimulation on fine motor functions in medication-resistant major depression" 66 : 252-258, 2012

21 George MS, "The expanding evidence base for rTMS treatment of depression" 26 : 13-18, 2013

22 Brunelin J, "The efficacy and safety of low frequency repetitive transcranial magnetic stimulation for treatment-resistant depression: the results from a large multicenter French RCT" 7 : 855-863, 2014

23 Choi KM, "The effects of 3 weeks of rTMS treatment on P200 amplitude in patients with depression" 577 : 22-27, 2014

24 Perera T, "The clinical TMS society consensus review and treatment recommendations for TMS therapy for major depressive disorder" 9 : 336-346, 2016

25 Kreuzer PM, "The ACDC pilot trial: targeting the anterior cingulate by double cone coil rTMS for the treatment of depression" 8 : 240-246, 2015

26 Chen SJ, "Superior antidepressant effect occurring 1 month after rTMS: add-on rTMS for subjects with medication-resistant depression" 9 : 397-401, 2013

27 Slotema CW, "Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders" 71 : 873-884, 2010

28 Baeken C, "Self-directedness: an indicator for clinical response to the HF-rTMS treatment in refractory melancholic depression" 220 : 269-274, 2014

29 Hadley D, "Safety, tolerability, and effectiveness of high doses of adjunctive daily left prefrontal repetitive transcranial magnetic stimulation for treatment-resistant depression in a clinical setting" 27 : 18-25, 2011

30 Chistyakov AV, "Safety, tolerability and preliminary evidence for antidepressant efficacy of theta-burst transcranial magnetic stimulation in patients with major depression" 13 : 387-393, 2010

31 Berlim MT, "Response, remission and drop-out rates following high-frequency repetitive transcranial magnetic stimulation (rTMS) for treating major depression: a systematic review and meta-analysis of randomized, double-blind and sham-controlled trials" 44 : 225-239, 2014

32 Rosenberg O, "Response to deep TMS in depressive patients with previous electroconvulsive treatment" 3 : 211-217, 2010

33 Mosimann UP, "Repetitive transcranial magnetic stimulation: a putative add-on treatment for major depression in elderly patients" 126 : 123-133, 2004

34 Grunhaus L, "Repetitive transcranial magnetic stimulation is as effective as electroconvulsive therapy in the treatment of nondelusional major depressive disorder: an open study" 47 : 314-324, 2000

35 Health Quality Ontario, "Repetitive transcranial magnetic stimulation for treatment-resistant depression: a systematic review and meta-analysis of randomized controlled trials" 16 : 1-66, 2016

36 Brunoni AR, "Repetitive transcranial magnetic stimulation for the acute treatment of major depressive episodes: a systematic review with network meta-analysis" 74 : 143-152, 2017

37 Bretlau LG, "Repetitive transcranial magnetic stimulation (rTMS) in combination with escitalopram in patients with treatment-resistant major depression:a double-blind, randomised, sham-controlled trial" 41 : 41-47, 2008

38 Chistyakov AV, "Preliminary assessment of the therapeutic efficacy of continuous theta-burst magnetic stimulation (cTBS) in major depression:a double-blind sham-controlled study" 170 : 225-229, 2015

39 Brakemeier EL, "Patterns of response to repetitive transcranial magnetic stimulation (rTMS) in major depression: replication study in drug-free patients" 108 : 59-70, 2008

40 Bosaipo NB, "Neuropsychological changes in melancholic and atypical depression: A systematic review" 73 : 309-325, 2017

41 Ruohonen J, "Navigated transcranial magnetic stimulation" 40 : 7-17, 2010

42 Grunhaus L, "Monitoring the response to rTMS in depression with visual analog scales" 17 : 349-352, 2002

43 Dunjic-Kostic B, "Melancholic and atypical major depression--connection between cytokines, psychopathology and treatment" 43 : 1-6, 2013

44 Kayser S, "Magnetic seizure therapy in treatment-resistant depression:clinical, neuropsychological and metabolic effects" 45 : 1073-1092, 2015

45 Eche J, "Low- vs high-frequency repetitive transcranial magnetic stimulation as an add-on treatment for refractory depression" 3 : 13-, 2012

46 Nahas Z, "Left prefrontal transcranial magnetic stimulation (TMS) treatment of depression in bipolar affective disorder: a pilot study of acute safety and efficacy" 5 : 40-47, 2003

47 Rosenquist PB, "Left dorsolateral prefrontal transcranial magnetic stimulation (TMS):sleep factor changes during treatment in patients with pharmacoresistant major depressive disorder" 205 : 67-73, 2013

48 Holzer M, "Intermittent theta burst stimulation (iTBS)ameliorates therapy-resistant depression: a case series" 3 : 181-183, 2010

49 Hernández-Ribas R, "Identifying brain imaging correlates of clinical response to repetitive transcranial magnetic stimulation (rTMS) in major depression" 6 : 54-61, 2013

50 Fox MD, "Identification of reproducible individualized targets for treatment of depression with TMS based on intrinsic connectivity" 66 : 151-160, 2013

51 Zheng H, "High-frequency rTMS treatment increases left prefrontal myo-inositol in young patients with treatment-resistant depression" 34 : 1189-1195, 2010

52 Baeken C, "HF-rTMS treatment decreases psychomotor retardation in medication-resistant melancholic depression" 34 : 684-687, 2010

53 Harel EV, "H-coil repetitive transcranial magnetic stimulation for treatment resistant major depressive disorder: an 18-week continuation safety and feasibility study" 15 : 298-306, 2014

54 Harel EV, "H-coil repetitive transcranial magnetic stimulation for the treatment of bipolar depression: an add-on, safety and feasibility study" 12 : 119-126, 2011

55 Kang JI, "Frontostriatal connectivity changes in major depressive disorder after repetitive transcranial magnetic stimulation: a randomized shamcontrolled study" 77 : e1137-e1143, 2016

56 Herrmann LL, "Factors modifying the efficacy of transcranial magnetic stimulation in the treatment of depression: a review" 67 : 1870-1876, 2006

57 Sienaert P, "Evidence-based treatment strategies for treatment-resistant bipolar depression: a systematic review" 15 : 61-69, 2013

58 Lefaucheur JP, "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)" 125 : 2150-2206, 2014

59 Veronezi BP, "Evidence for increased motor cortical facilitation and decreased inhibition in atypical depression" 134 : 172-182, 2016

60 Couturier JL, "Efficacy of rapid-rate repetitive transcranial magnetic stimulation in the treatment of depression: a systematic review and meta-analysis" 30 : 83-90, 2005

61 Li CT, "Efficacy of prefrontal theta-burst stimulation in refractory depression:a randomized sham-controlled study" 137 (137): 2088-2098, 2014

62 Levkovitz Y, "Efficacy and safety of deep transcranial magnetic stimulation for major depression: a prospective multicenter randomized controlled trial" 14 : 64-73, 2015

63 Rosenberg O, "Effectiveness of a second deep TMS in depression: a brief report" 35 : 1041-1044, 2011

64 Bermpohl F, "Effect of low-frequency transcranial magnetic stimulation on an affective go/no-go task in patients with major depression: role of stimulation site and depression severity" 141 : 1-13, 2006

65 Cheng CM, "Different forms of prefrontal theta burst stimulation for executive function of medication- resistant depression: evidence from a randomized sham-controlled study" 66 : 35-40, 2016

66 Gaudiano BA, "Depressive symptom profiles and severity patterns in outpatients with psychotic vs nonpsychotic major depression" 49 : 421-429, 2008

67 Levkovitz Y, "Deep transcranial magnetic stimulation over the prefrontal cortex: evaluation of antidepressant and cognitive effects in depressive patients" 2 : 188-200, 2009

68 Bersani FS, "Deep transcranial magnetic stimulation for treatment-resistant bipolar depression: a case report of acute and maintenance efficacy" 19 : 451-457, 2013

69 Bersani FS, "Deep transcranial magnetic stimulation as a treatment for psychiatric disorders: a comprehensive review" 28 : 30-39, 2013

70 Kedzior KK, "Deep transcranial magnetic stimulation (DTMS) in the treatment of major depression:An exploratory systematic review and meta-analysis" 187 : 73-83, 2015

71 Rosenberg O, "Deep TMS in a resistant major depressive disorder: a brief report" 27 : 465-469, 2010

72 George MS, "Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial" 67 : 507-516, 2010

73 Lisanby SH, "Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: clinical predictors of outcome in a multisite, randomized controlled clinical trial" 34 : 522-534, 2009

74 Isserles M, "Cognitive-emotional reactivation during deep transcranial magnetic stimulation over the prefrontal cortex of depressive patients affects antidepressant outcome" 128 : 235-242, 2011

75 Berlim MT, "Clinically meaningful efficacy and acceptability of low-frequency repetitive transcranial magnetic stimulation (rTMS) for treating primary major depression: a meta-analysis of randomized, double-blind and shamcontrolled trials" 38 : 543-551, 2013

76 Prasser J, "Bilateral prefrontal rTMS and theta burst TMS as an add-on treatment for depression: a randomized placebo controlled trial" 16 : 57-65, 2015

77 Berlim MT, "Augmenting antidepressants with deep transcranial magnetic stimulation (DTMS) in treatment-resistant major depression" 15 : 570-578, 2014

78 Dell’Osso B, "Augmentative repetitive navigated transcranial magnetic stimulation (rTMS) in drug-resistant bipolar depression" 11 : 76-81, 2009

79 Luber B, "Applications of transcranial magnetic stimulation and magnetic seizure therapy in the study and treatment of disorders related to cerebral aging" 15 : 87-98, 2013

80 Kayser S, "Antidepressant effects, of magnetic seizure therapy and electroconvulsive therapy, in treatment-resistant depression" 45 : 569-576, 2011

81 Rapinesi C, "Antidepressant effectiveness of deep Transcranial Magnetic Stimulation (dTMS) in patients with Major Depressive Disorder (MDD) with or without Alcohol Use Disorders (AUDs): a 6-month, open label, follow-up study" 174 : 57-63, 2015

82 Demirtas-Tatlidede A, "An open-label, prospective study of repetitive transcranial magnetic stimulation (rTMS) in the long-term treatment of refractory depression: reproducibility and duration of the antidepressant effect in medication-free patients" 69 : 930-934, 2008

83 Aguirre I, "Age predicts low-frequency transcranial magnetic stimulation efficacy in major depression" 130 : 466-469, 2011

84 Duprat R, "Accelerated intermittent theta burst stimulation treatment in medication-resistant major depression: a fast road to remission?" 200 : 6-14, 2016

85 Lepping P, "A systematic review of the clinical relevance of repetitive transcranial magnetic stimulation" 130 : 326-341, 2014

86 Berlim MT, "A systematic review and meta-analysis on the efficacy and acceptability of bilateral repetitive transcranial magnetic stimulation (rTMS) for treating major depression" 43 : 2245-2254, 2013

87 Rossini D, "A symptom-specific analysis of the effect of high-frequency left or low-frequency right transcranial magnetic stimulation over the dorsolateral prefrontal cortex in major depression" 62 : 91-97, 2010

88 Fitzgerald PB, "A randomized trial of rTMS targeted with MRI based neuronavigation in treatment-resistant depression" 34 : 1255-1262, 2009

89 Mogg A, "A randomized controlled trial with 4-month follow-up of adjunctive repetitive transcranial magnetic stimulation of the left prefrontal cortex for depression" 38 : 323-333, 2008

90 Fitzgerald PB, "A negative double-blind controlled trial of sequential bilateral rTMS in the treatment of bipolar depression" 198 : 158-162, 2016