가토의 아킬레스건 파열의 수술적 치료 후 고정 방법에 따른 생역학적 및 조직학적 변화

국문 초록 (Abstract)

목적: 아킬레스건 파열의 수술 후 고정 방법에 따른 생역학적 및 조직학적 결과를 비교하였다.
대상 및 방법: 30마리의 수컷 가토의 우측 아킬레스건을 절단 후 변형된 Kessler씨 방법으로 봉합하였고, 수술하지 않은 좌측은 대조군으로 하였다. Ⅰ군(n＝10)은 족저 굴곡 상태로 장하지 석고를 6주간 고정하였고, Ⅱ군(n＝10)은 수술 1주일째부터 전신 마취하에 1주일 간격으로 교정하여 수술 5주에는 완전히 배측 굴곡시켜 고정하였다. Ⅲ군(n＝l이은 외고정 장치를 경골과 종골에 고정 후 수술 1주부터 완전히 배측 굴곡이 되도록 하루에 2㎜씩 외고정 장치를 단축시켰다. 수술 6 주에 아킬레스건을 종골의 부착 부위에서 절단하여 각 군의 5마리는 생역학적 실험을 실시하였고 나머지 5마리는 조직 검사를 하였다.
결과: 생역학 검사에서 제Ⅰ, Ⅱ, Ⅲ, 대조군에서 파열 하중(N)은 각각 55.50, 97.46, 140.27, 180.98이었으며, 변형률은 0.44, 0.49, 0.74, 0.67이었으며, 파열에 필요한 에너지(J)는 12.23, 23.98, 51.20, 60.78이었으며, 강도(N/㎜)는 9.63, 17.87, 19.01, 23.33이었다. 제Ⅰ, Ⅱ, Ⅲ 군간 파괴 하중, 변형률, 파열에 필요한 에너지 그리고 강도가 Ⅲ군으로 갈수록 증가하였으며, 통계학적 유의성이 있었다(p＜0.05). 조직학 소견 상 Ⅲ군으로 갈수록 건 구조가 보다 성숙되어 있었으며, 섬유 다발이 보다 평행한 배열 양상을 보였다.
결론: 수술 후 치유 중의 아킬레스건의 연속적인 교정에 의한 인장력은 생역학 및 조직학적으로 보다 정상에 유사한 회복 양상을 나타낸다.

다국어 초록 (Multilingual Abstract)

Purpose: To evaluate the effects of the different regimens of immobilization after surgery in a rabbit model.
Materials and Methods: The study was performed on the right Achilles tendon of 30 rabbits. Modified Kessler method was used to suture the transected tendon. Rabbits were divided into three groups, Group Ⅰ (n＝10) underwent long leg cast with equinus position for 6 weeks, Group Ⅱ (n＝10) underwent weekly cast correction to full dorsiflexion from 1 week after surgery, and Group Ⅲ (n＝10) underwent daily correction of equinous position with external fixator from 1 week after surgery. The contralateral Achilles tendon served as an un operated control. And three groups were compared at 6 weeks after surgery.
Results: The maximal load at rupture (N) was 55.50, 97.46, 140.27, 180.98 for group Ⅰ, Ⅱ, Ⅲ and control respectively. The strain was 0.44, 0.49, 0.74, 0.67. The stiffness (N/㎜) was 9.63, 17.87, 19.01, 23.33. The absorbed energy to rupture (J) was 12.23, 23.98, 51.20, 60.78. Values among groups were significantly different considering the maximal load, strain, stiffness, and absorbed energy to rupture (p＜0.05). Histological finding was revealed more mature restoration and more parallel arrangement of fiber bundles in the group Ⅱ, and especially group Ⅲ. Achilles tendon rupture, Maximal load, Strain, Stiffness, Tensile loading.
Conclusion: Tensile loading of the healing tendon by postoperative continuous correction leads to changes in more similar to the normal Achilles tendon, biomechanically and historically.

목차 (Table of Contents)

• 대상 및 방법
• 결과
• 고찰
• 결론
• 참고문헌

참고문헌 (Reference)

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