내시경 역행성 담췌관 조영술 후 발생한 췌장염의 예측인자로서 혈청 procalcitonin의 효용성 = Estimating the Diagnostic Accuracy of Procalcitonin as a Marker for Post-ERCP Pancreatitis

다국어 초록 (Multilingual Abstract)

Backgrounds/Aims: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). We wanted to evaluate serum procalcitonin as a marker for early prediction of post-ERCP pancreatitis. Methods: Prospective single center study of 94 patients undergoing ERCP between November 2011 and July 2012 were performed. Blood samples for serum procalcitonin were obtained immediately, 4 hours, and 24 hours after ERCP. The definition of post-ERCP pancreatitis and the grade of its severity were based on consensus criteria Result: The incidence of post-ERCP pancreatitis was 16.0% (15 patients). Thirteen had mild pancreatitis, 2 had moderate pancreatitis, and none had severe pancreatitis. The procalcitonin levels in post-ERCP pancreatitis group and no pancreatitis group were 0.28±0.38 vs. 0.47±0.58 ng/ml for immediately, 0.31±0.42 vs. 0.45±0.53 ng/ml for 4 hours and 0.28±0.39 vs. 0.46±0.46 ng/ml for 24 hours. The levels of serum procalcitonin were not significantly different between post-ERCP pancreatitis group and no pancreatitis group (p=0.129 for immediately, p=0.275 for 4 hours, and p=0.266 for 24 hours) Conclusion: There was no significant difference in the level of serum procalcitonin level between post-ERCP pancreatitis and no pancreatitis group.