만성 광선 피부염 12예에 대한 임상적 고찰 = Clinical Study of 12 Cases with Chronic Actinic Dermatitis만성 광선 피부염 12예에 대한 임상적 고찰

다국어 초록 (Multilingual Abstract)

Background: Chronic actinic dermatitis (CAD) has been defined using three criteria: clinical photobiological and histological aspects. CAD is a rare disease with only a few clinical analyses reported in Korea. Objective: The purpose of this study was to investigate the clinical characteristics of CAD including epidemiology, clinical presentations and results of phototests in Korean patients. Methods: A retrospective analysis was conducted according to patients` medical records at Seoul National University Hospital. Results: Twelve patients were enrolled in this study. Most were elderly men with skin lesions on the sun-exposed areas. The mean age was 55. 4 years. Ten patients were male and the other 2 were female. The mean duration of the disease was 12.7 years. Phototests showed that 6 patients showed decreased minimal erythema dose (MED) to UVA and 2 patients decreased MED to UVB. The remaining 4 patients decreased to both UVA and UVB. Conclusion: The most common abnormal phototest results were decreased MED to UVA. More patients showed normal MED to UVB in this study compared with other studies. Our study analyzed the clinical and photobiological characteristics of CAD in Korean patients. (Korean J Dermatol 2007;45(11):1144∼1148)

참고문헌 (Reference)

1 "response to cyclosporine" 307-308, jamacaddermatol1989

2 "Treatment of chronic actinic dermatitis with tacrolimus ointment" 47 : 881-884, 2002

3 "The syndrome of chronic photosensitivity dermatitis and actinic reticuloid" 91 : 617-634, 1974

4 "The natural history of chronic actinic dermatitis" 136 : 1215-1220, 2000

5 "The idiopathic photodermatoses: chronic actinic dermatitis" 190-202, 1999

6 "Results of photopatch and patch tests in 35 Korean patients with chronic actinic dermatitis and clinical importance of these findings" 42 : 976-982, 2004

7 "Preventive treatment of sunburn and skin cancer with sun protective agents Dermatology in general medicine" McGraw-Hill 1689-1696, 1993

8 "Photosensitive eczema" 59 : 152-158, 1973

9 "Photomedicine" Seoul: Ryo moon gak 196-206, 1994

10 "PUVA therapy of chronic actinic dermatitis" 113 : 157-160, 1985

11 "Immediate and delayed pigmentary and other cutaneous responses to solar UVA radiation The biological effects of 자외선A radiation" Praeger Publishers 164-165, 1986

12 "Clinical study for the photosensitive disease" 39 : 972-978, 2001

13 "Classification of the skin phototype according to UVB induced minimal erythema dose in young korean adults" 34 : 893-897, 1996

14 "Chronic actinic dermatitis:an analysis of 51 patients in the United States and Japan" 130 : 1284-1289, 1994

15 "Chronic actinic dermatitis:a unifying concept" 126 : 376-378, 1990

16 "Chronic actinic dermatitis:a retrospective analysis of 44 cases referred to an Australian photobiology clinic" 44 : 256-62, 2003

17 "Chronic actinic dermatitis" 20 : 312-314, 2004

18 "Azathoprine treatment in chronic actinic dermatitis a double-blind controlled trial with monitoring of exposure to ultraviolet radiation" 639-646, brjdermatol1989

19 "Actinic reticuloid:a chronic dermatosis associated with severe photosensitivity and the histological resemblance to lymphoma" 81 : 469-485, 1969

20 "A clinical analysis of 11 patients with chronic actinic dermatitis in Korea" 41 : 190-194, 2000