본태성 고혈압 환자 적혈구막의 Na+ - Li+ Countertransport 에 관한 연구 = Na+ - Li+ Countertransport in Red Blood Cells in Patients with Essential Hypertension

다국어 초록 (Multilingual Abstract)

N/A

다국어 초록 (Multilingual Abstract)

In order to investigate the changes of Na+ transport system of the red blood cells in patients with essential hypertension, N+-Li+ countertransport was measured in 30 cases of essential hypertension and 20healthy normal controls. Furthermore, these measurements were analyzed in terms of some important clinical parameters in patients with essential hypertension, i.r., body mass index (BMI), status of hypertension, and plasma lipids. Na+-Li+ countertransport in the patient group significantly increased compared with the control group (62.2±4.5 and 46.8±3.0㎛ol/L cells.hr). In the analysis regarding the relationship between the Na+-Li+ countertransport system and some important clinical parameters of the patients with essential hypertension, Na+-Li+ countertransport was related to BMI, and the level of triglycerides did not show any significant relationship with the level of blood pressure, WHO class, and the level of cholesterol. These results suggest that Na+-Li+ countertransport systems in essential hypertensive patients were significantly altered compared with normal healthy controls but overlapped considerably between the 2groups.