Formocresol,Glutaraldehyde의 접촉시간에 따른 성견치수의 병리조직학적 연구 = A HISTOPATHOLOGICAL STUDY ON THE PULP TISSUE REACTIONS TO FORMOCRESOL AND GLUTARALDEHYDE AT THE DIFFERENT TIME INTERVALS OF APPLICATION IN DOGS

다국어 초록 (Multilingual Abstract)

The purpose of this study is to observe the histopathological changes of the pulp tissue after vital pulpotomy with formocresol or glutaraldehyde at the different time intervals of application. Upper and lower teeth in seven dogs, aged about 1 years, were subjected to pulp amputations and were divided into two groups, one of which ws pulpotomized with formocresol, the other was with glutaraldehyde. The application was performed at the intervals of 1 minute, 3 minutes, 5 minutes, 3 days and 7 days, and then the experimental animals were sacrificed 2 months after the last experiment.
THe excised jaw bones were fixed in 10% neutral buffered formalin solutions, and they were routinely decalcified in 5% nitric acid, and embedded in paraffin, and sections were stained with hematoxylin and eosin and observed with light microscope.
Following results were obtained.
1. In the formocresol 1 minute-, 3 minute-, 3 day- and 7 day- groups and the glutaraldehyde 1 minute-, 3 day- and 7 day- groups, the pulp tissue responses varied from normal pulp tissue findings to total coagulation necrosis.
2. In the formocresol 5 minute- group and the glutaraldehyde 3 minute- and 5 minute- groups, they showed slight inflammation and the almost typical morphology of normal pulp tissue.
3. In the almost formocresol and glutaradehyde groups, reparative dentin was formed.
4. Dentinal resorption in the formocresol group was more frequent than that in the glutaraldehyde group.