We present here experiences of 81 cases with transcervical chorionic villus sampling(CVS) at Kyung Hee University Hospital. At Kyung Hee University Hospital, we have currently performed CVS in continuing pregnancy since February, 1989. As of end-Septe...
We present here experiences of 81 cases with transcervical chorionic villus sampling(CVS) at Kyung Hee University Hospital. At Kyung Hee University Hospital, we have currently performed CVS in continuing pregnancy since February, 1989. As of end-September, 1989, we performed transcervical CVS in 81 pregnant women. The cytogenetic analysis routinely used were direct(cytotrophoblast) and culture(mesenchymal core) karyotyping. Overall success rate in obtaining villi samples is 95.1%(77/81 subjects), and mean amount of recovered villi is 19.07 10.27 mg and mean number of catheter passes is 1.73 0.77. Of 81 attempted cases, spontaneous abortion occurred in one case indication 1.21%(1/81) of abortion rate. Location of chorionic frondosum seems to play a major role in success of transcervical CVS. CVS is most difficult in cases of posterior or fundal location of chorionic frondosum. Neither maternal cell contamination nor culture failure were yet noted in our CVS program.