OK-432(Picibanilⓡ)와 외과적 절제술을 이용한 선천성 림프관종의 치험례 = THE TREATMENT OF CONGENITAL LYMPHANGIOMA WITH OK-432(PICIBANILⓡ)AND SURGICAL EXCISION

다국어 초록 (Multilingual Abstract)

Lymphangiomas are relatively rare benign tumors of the lymphatic system, characterized by congenital lymphatic malformation such as anastomosis or obstuction of the lymphatic channels.
There are most frequently diagnosed in children younger than 3years. In contrast to that of the hemangioma, the sex distribution of the lymphangioma is nearly evenly divided. The head and neck lymphangioma represents about 70∼75% of all lymphangiomas, and they are difficult to manage.
Spontaneous regression is rare, and rapid intermittent enlargement occurs secondary to infection or trauma. Enlargement may cause serious sequelae such as airway obstruction, feeding difficulties, and cosmetic problems.
Treatments previously used for lymphangiomas include surgical excision and intralesional injection of sclerosants. Problems associated with surgical excision include the risk of cosmetically unacceptable scarring and the risk of damage to surrounding vital stricture and the high risk of incomplete excision. The sclerosants previously used have numerous other local and systemic side effects.
This report describes a case that was successfully treated using OK-432 as a new sclerosant drug and secondary surgical excision for congential cavenous lymphangioma extensively enlarged to tongue, mouth floor and submandibular region.

목차 (Table of Contents)

• Ⅰ.서론
• Ⅱ.증례보고
• Ⅲ.총괄 및 고찰
• Ⅳ.요약