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      한국 하지불안증후군 환자의 삶의 질: 다른 만성질환과 비교 = Quality of Life in Patients With Restless Legs Syndrome in Korea: Comparison With Other Chronic Diseases

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      https://www.riss.kr/link?id=A101608295

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      다국어 초록 (Multilingual Abstract) kakao i 다국어 번역

      Background: We studied the quality of life (QOL) of patients with restless legs syndrome (RLS) and compared it to that of normal controls and patients with hypertension or diabetes in Korea.
      Methods: We developed a Korean version of the Johns Hopkins RLS QOL questionnaire by translating this into Korean and then back into English to check its accuracy. In total, 250 RLS patients were included in this study.
      The scores of RLS patients were compared with those of 215 normal controls, 196 patients with hypertension, and 185 diabetics. All subjects completed the questionnaires, including the Korean versions of the Short Form 36, Johns Hopkins RLS QOL, Pittsburgh Sleep Quality Index, and the Beck Depression Inventory. The associations between the severity of RLS and the QOL scores were examined using Pearson correlations.
      Results: The QOL scores were lower in subjects with RLS than in the normal controls and the patients with hypertension or diabetes. More severe RLS symptoms were associated with a lower QOL score. Correlation analysis revealed a significant negative correlation between the severity of RLS symptoms and QOL score (r=–0.702, p<0.001). However, neither the gender of the RLS subjects nor the age at symptom onset (early or late onset) affected the QOL score. The factors most related to QOL score in RLS patients were depression and sleep quality.
      Conclusions: We found that Koreans with RLS have a considerably diminished QOL, with this being worse than in Korean subjects with diabetes or hypertension. These findings are comparable with studies conducted in Western countries.
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      Background: We studied the quality of life (QOL) of patients with restless legs syndrome (RLS) and compared it to that of normal controls and patients with hypertension or diabetes in Korea. Methods: We developed a Korean version of the Johns Hopkins ...

      Background: We studied the quality of life (QOL) of patients with restless legs syndrome (RLS) and compared it to that of normal controls and patients with hypertension or diabetes in Korea.
      Methods: We developed a Korean version of the Johns Hopkins RLS QOL questionnaire by translating this into Korean and then back into English to check its accuracy. In total, 250 RLS patients were included in this study.
      The scores of RLS patients were compared with those of 215 normal controls, 196 patients with hypertension, and 185 diabetics. All subjects completed the questionnaires, including the Korean versions of the Short Form 36, Johns Hopkins RLS QOL, Pittsburgh Sleep Quality Index, and the Beck Depression Inventory. The associations between the severity of RLS and the QOL scores were examined using Pearson correlations.
      Results: The QOL scores were lower in subjects with RLS than in the normal controls and the patients with hypertension or diabetes. More severe RLS symptoms were associated with a lower QOL score. Correlation analysis revealed a significant negative correlation between the severity of RLS symptoms and QOL score (r=–0.702, p<0.001). However, neither the gender of the RLS subjects nor the age at symptom onset (early or late onset) affected the QOL score. The factors most related to QOL score in RLS patients were depression and sleep quality.
      Conclusions: We found that Koreans with RLS have a considerably diminished QOL, with this being worse than in Korean subjects with diabetes or hypertension. These findings are comparable with studies conducted in Western countries.

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      참고문헌 (Reference)

      1 Walters AS, "legs syndrome. The International Restless Legs Syndrome Study Group" 10 : 634-642, 1995

      2 Buysse DJ, "The Pittsburgh Sleep quality Index: a new instrument for psychiatric practice and research" 28 : 193-213, 1989

      3 Ware JE, "The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection" 30 : 473-483, 1992

      4 Backhaus J, "Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia" 53 : 737-740, 2002

      5 Gorman CA, "Symptoms of restless legs" 115 : 155-160, 1965

      6 Berger K, "Sex and risk of restless legs syndrome in the general population" 164 : 196-202, 2004

      7 Allen RP, "Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health" 4 : 101-119, 2003

      8 Hogl B, "Restless legs syndrome: a community-based study of prevalence, severity, and risk factors" 64 : 1920-1924, 2005

      9 Allen RP, "Restless legs syndrome prevalence and impact: REST general population study" 165 : 1286-1292, 2005

      10 Milligan SA, "Restless legs syndrome in the older adult: diagnosis and management" 19 : 741-751, 2002

      1 Walters AS, "legs syndrome. The International Restless Legs Syndrome Study Group" 10 : 634-642, 1995

      2 Buysse DJ, "The Pittsburgh Sleep quality Index: a new instrument for psychiatric practice and research" 28 : 193-213, 1989

      3 Ware JE, "The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection" 30 : 473-483, 1992

      4 Backhaus J, "Test-retest reliability and validity of the Pittsburgh Sleep Quality Index in primary insomnia" 53 : 737-740, 2002

      5 Gorman CA, "Symptoms of restless legs" 115 : 155-160, 1965

      6 Berger K, "Sex and risk of restless legs syndrome in the general population" 164 : 196-202, 2004

      7 Allen RP, "Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health" 4 : 101-119, 2003

      8 Hogl B, "Restless legs syndrome: a community-based study of prevalence, severity, and risk factors" 64 : 1920-1924, 2005

      9 Allen RP, "Restless legs syndrome prevalence and impact: REST general population study" 165 : 1286-1292, 2005

      10 Milligan SA, "Restless legs syndrome in the older adult: diagnosis and management" 19 : 741-751, 2002

      11 Bjorvatn B, "Prevalence, severity and risk factors of restless legs syndrome in the general adult population in two Scandinavian countires" 6 : 307-312, 2005

      12 Rothdach AJ, "Prevalence and risk factors of RLS in an elderly population: the MEMO Study. Memory and Morbidity in Augsburg Elderly" 54 : 1064-1068, 2000

      13 McCrink L, "Predictors of health-related quality of life in sufferers with restless legs syndrome: A multi-national study" 8 : 73-83, 2007

      14 O’Keeffe ST, "Iron status and restless legs syndorme in the elderly" 23 : 200-203, 1994

      15 Sun ER, "Iorn and the restless legs syndrome" 21 : 371-377, 1998

      16 Wetter TC, "Functional neuroimaging studies in restless legs syndrome" 5 : 401-406, 2004

      17 Hening W, "Ferini Strambi L. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST primary care study" 5 : 237-246, 2004

      18 Allen RP, "Factor analysis of the International Restless Legs Syndrome Study Group’s scale for restless legs severity" 4 : 133-135, 2003

      19 Abetz L, "Evaluating the quality of life of patients with restless legs syndrome" 26 : 925-935, 2004

      20 Cho YW, "Epidemiology of restless legs syndrome in Korean Adults" 31 : 219-223, 2008

      21 Tison F, "Epidemiology of restless legs syndrome in French adults: a nationwide survey: the INSTANT study" 65 : 239-246, 2005

      22 Phillips B, "Epidemiology of restless legs symptoms in adults" 160 : 2137-2141, 2000

      23 Kim JM, "Depression and anxiety in patients with restless legs syndrome" 2010

      24 Allen RP, "Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset" 1 : 11-19, 2000

      25 Earley CJ, "Clinical practice. Restless legs syndrome" 348 : 2103-2109, 2003

      26 Kushida C, "Burden of restless legs syndrome on health-related quality of life" 16 : 617-624, 2007

      27 Winkelman JW, "Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study" 70 : 35-42, 2008

      28 Beck AT, "Assessment of depression: the depression inventory" 7 : 151-166, 1974

      29 Happe S, "Assessing health-related quality of life in patients with restless legs syndrome" 10 : 295-305, 2009

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