About 10-20% of patients who present with acute idiopathic thrombocytopenic purpura(ITP) and who have persistent thrombocytopenia for more than 6 months have choronic ITP. Treatment requires differentiating the truly idiopathic state from thrombocytop...
About 10-20% of patients who present with acute idiopathic thrombocytopenic purpura(ITP) and who have persistent thrombocytopenia for more than 6 months have choronic ITP. Treatment requires differentiating the truly idiopathic state from thrombocytopenias associated with order disorders. Therapeutic options of included corticosteroid, intravenous immunoglobulin(IVIG), and anti-D, as well as splenectomy. Good results were obtained in many chronic ITP patients treated with intravenous anti-D. immunoglobulin. The advantage of anti-D in chronic ITP patients is ease of administration and lower cost as compared to IVIG. We recently treated 4 cases of Rh(D+) chronic ITP patients with intravenous anti-D.