말단비대증과 위암을 동반한 당뇨병 환자에서 발생한 뇌하수체 모균증 1예 = A Case of Pituitary Mucormycosis in Diabetic Patient with Acromegaly and Gastric Cancer

다국어 초록 (Multilingual Abstract)

Rhino-orbito-cerebral mucormycosis (ROCM) is an uncommon, acute, and aggressive fungal infection occurring in several immunocompromised states including poorly controlled diabetes. ROCM causes a very high residual morbidity and mortality due to the angioinvasion property of the fungus. Acromegaly is a chronic condition resulting from the excessive secretion of growth hormone, generally from pituitary adenoma. Although it has been demonstrated that acromegalic patients have an increased risk of neoplasm, gastric cancer with acromegaly is very rare. We experienced a case of pituitary mucormycosis in the diabetic patient with acromegaly and gastric cancer. The patient was treated successfully with subtotal gastrectomy for early gastric cancer, transsphenoidal surgery for pituitary adenoma, and a systemic application of amphotericin B for the mucormycosis. (J Kor Soc Endocrinol 21:245~250, 2006)

국문 초록 (Abstract)

모균증은 진균에 의해 발생하는 질환으로 여러 면역질환에서 잘 감염되나 그 중 당뇨병에서 가장 호발한다고 한다. 모균증 중 비대뇌형이 가장 흔하며 직접 또는 혈행성으로 두개강 내로 전파되기 때문에 치료가 지연되거나 충분하지 않을 경우 치명적인 경과를 갖게 된다. 저자들은 위암과 당뇨병을 가진 환자에서 동반된 말단비대증 환자에서 경접형동 종양제거술을 시행하였으며, 선종의 수술 후 병리조직소견상 뇌하수체에서 발생한 모균증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

참고문헌 (Reference)

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