미니돼지의 성장특성에 관한 연구 = Study of The Growth Related Characteristics in Miniature Pigs

다국어 초록 (Multilingual Abstract)

Miniature pigs are a small and improved variety of regular pigs and are currently widely used as pets. With the development of medicine and biotechnology following the completion of the human genome project, the use of miniature pigs has become more specific and the scope of use has expanded. Since many experimental animals need to use mini pigs as experimental animals, miniature pigs, which are more expensive than mice, have the disadvantage of being less useful due to higher production costs. Therefore, miniaturization is urgent to increase the value of use as an experimental animal. To miniaturize mini pigs, factors that can change at the gene or DNA level must be found, and feed types and nutrition must be improved by indicators rather than other environmental changes. In this article, we investigated the growth characteristics of miniature pigs by breed to find genetic indicators for the miniaturization of miniature pigs. In the case of eight breeds known as major miniature pigs, the characteristics of each breed were classified and the growth characteristics of this breed were encapsulated. Furthermore, biological comparisons of regular pigs, micro pigs, and miniature pigs were carried out, and finally, the effects on pig growth were investigated and explained. Through this study, it is expected that the cause of the growth difference between mini pigs and ordinary pigs will be identified and basic data will be provided as an indicator of miniature pigs' miniaturization by analyzing and organizing factors that can affect the varieties, origin, and growth of miniature pigs.

국문 초록 (Abstract)

미니돼지는 일반돼지를 소형화 개량한 품종으로서 현재는 애완용으로도 많이 이용되는 동물이다. 최근 의학의 발달과 인간게놈프로젝트의 완료로 인한 생명공학 기술의 발전으로 미니돼지에 대한 활용방안이 보다 더 구체화되고 이용범위가 광범위해졌다. 실험동물로서 미니돼지를 이용하기 위하여 다수의 실험동물이 사용되어야 하는 특성상 쥐에 비해 고가인 미니돼지는 비싼생산비용으로 인해 그 활용성이 떨어지는 단점이 있다. 따라서 실험동물로서 활용가치를 높이기 위하여 미니돼지의 소형화가 시급하다. 미니돼지의 소형화를 위하여 사료형태나 영양상태를 달리하는 환경적 변화보다 근본적으로 유전적 수준이나 DNA 수준에서 변화시킬 수 있는 요인을 찾고, 그것을 지표로 개량을 해야한다. 본 논문에서는 미니돼지의 소형화를 위한 유전적 지표를 찾기 위하여 미니돼지의 품종별 성장특성을 알아내고자 하였다. 주요 미니돼지로 알려진 8종에 대하여 품종별 특징을 구분하였고, 이들 품종들의 성장특성에 대해 정리하였다. 추가로, 일반돼지와 마이크로돼지, 미니돼지의 생물학적 비교를 하였고, 마지막으로 돼지의 성장에 미치는 영향에 대해 조사 및 서술하였다. 본 연구를 통하여 현재까지 개발된 미니돼지의 품종과 기원, 성장에영향을 미칠 수 있는 요인을 분석 정리함으로써 최종적으로는 미니돼지와 일반돼지의 성장에 차이를 주는 원인을 밝히고 미니돼지의 소형화를 위한 지표로 활용할 수 있는 기초자료를 제공할 수 있을 것으로 기대한다.

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