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      A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature = A Report of 13 Cases of Merkel Cell Carcinoma: Single-Center Experience and Review of the Literature

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      https://www.riss.kr/link?id=A106182354

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      Background: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. Objective: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. Methods: Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved. Results: Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years. Conclusion: This is the first largest report from Turkish population with female predominance, and lower extremity tendency. (Ann Dermatol 31(3) 272∼278, 2019)
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      Background: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. Objective: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcom...

      Background: There is limited data knowledge of Merkel cell carcinoma (MCC) in Turkey aside from a few case reports. Objective: The aim of this study was to describe the clinical characteristics, demographic features, therapeutic parameters, and outcome of primary cutaneous MCC cases from Turkey. Methods: Digital medical records of the 13 MCC patients who were followed-up at a tertiary referral center were retrospectively analyzed. Clinic, demographic, tumor characteristics, and survival of the patients were retrieved. Results: Most of our patients were elderly. Female predominance was noticed. The most common primary site of the tumors was the lower extremities. The overall survival was 42 months, 68% at first year, 68% at third years, and 29% at fifth years. Conclusion: This is the first largest report from Turkish population with female predominance, and lower extremity tendency. (Ann Dermatol 31(3) 272∼278, 2019)

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      참고문헌 (Reference)

      1 Tilling T, "Which are the cells of origin in merkel cell carcinoma" 2012 : 680410-, 2012

      2 Dogu MH, "Two rare diagnoses during chronic lymphocytic leukaemia follow-up : Kaposi's sarcoma and Merkel cell carcinoma" 61 : 60-63, 2016

      3 Eng TY, "Treatment of merkel cell carcinoma" 27 : 510-515, 2004

      4 Toker C, "Trabecular carcinoma of the skin" 105 : 107-110, 1972

      5 Song PI, "The clinical profile of Merkel cell carcinoma in mainland China" 51 : 1054-1059, 2012

      6 Bajetta E, "Single-institution series of early-stage Merkel cell carcinoma : long-term outcomes in 95 patients managed with surgery alone" 16 : 2985-2993, 2009

      7 Saxena A, "Risk of second cancers in merkel cell carcinoma : a meta-analysis of population based cohort studies" 2014 : 184245-, 2014

      8 Lyhne D, "Rising incidence of Merkel cell carcinoma" 45 : 274-280, 2011

      9 Lemos BD, "Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma : analysis of 5823cases as the basis of the first consensus staging system" 63 : 751-761, 2010

      10 Tessari G, "Nonmelanoma skin cancer in solid organ transplant recipients : update on epidemiology, risk factors, and management" 38 : 1622-1630, 2012

      1 Tilling T, "Which are the cells of origin in merkel cell carcinoma" 2012 : 680410-, 2012

      2 Dogu MH, "Two rare diagnoses during chronic lymphocytic leukaemia follow-up : Kaposi's sarcoma and Merkel cell carcinoma" 61 : 60-63, 2016

      3 Eng TY, "Treatment of merkel cell carcinoma" 27 : 510-515, 2004

      4 Toker C, "Trabecular carcinoma of the skin" 105 : 107-110, 1972

      5 Song PI, "The clinical profile of Merkel cell carcinoma in mainland China" 51 : 1054-1059, 2012

      6 Bajetta E, "Single-institution series of early-stage Merkel cell carcinoma : long-term outcomes in 95 patients managed with surgery alone" 16 : 2985-2993, 2009

      7 Saxena A, "Risk of second cancers in merkel cell carcinoma : a meta-analysis of population based cohort studies" 2014 : 184245-, 2014

      8 Lyhne D, "Rising incidence of Merkel cell carcinoma" 45 : 274-280, 2011

      9 Lemos BD, "Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma : analysis of 5823cases as the basis of the first consensus staging system" 63 : 751-761, 2010

      10 Tessari G, "Nonmelanoma skin cancer in solid organ transplant recipients : update on epidemiology, risk factors, and management" 38 : 1622-1630, 2012

      11 Moshiri AS, "Milestones in the staging, classification, and biology of Merkel cell carcinoma" 12 : 1255-1262, 2014

      12 Esen BA, "Merkel-cell carcinoma arising after liver transplantation : a case report" 37 : 4413-4415, 2005

      13 Kukko H, "Merkel cell carcinoma-a population-based epidemiological study in Finland with a clinical series of 181 cases" 48 : 737-742, 2012

      14 Hohaus K, "Merkel cell carcinoma--a retrospective analysis of 17 cases" 17 : 20-24, 2003

      15 Pilloni L, "Merkel cell carcinoma with an unusual immunohistochemical profile" 53 : e33-, 2009

      16 Pectasides D, "Merkel cell carcinoma of the skin : a retrospective study of 24 cases by the Hellenic Cooperative Oncology Group" 72 : 211-218, 2007

      17 Albores-Saavedra J, "Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases : a population based study" 37 : 20-27, 2010

      18 Liang E, "Merkel cell carcinoma analysis of outcomes : a 30-year experience" 10 : e0129476-, 2015

      19 Allen PJ, "Merkel cell carcinoma : prognosis and treatment of patients from a single institution" 23 : 2300-2309, 2005

      20 Hodgson NC, "Merkel cell carcinoma : changing incidence trends" 89 : 1-4, 2005

      21 Coggshall K, "Merkel cell carcinoma : an update and review : pathogenesis, diagnosis, and staging" 78 : 433-442, 2018

      22 Tello TL, "Merkel cell carcinoma : an update and review : current and future therapy" 78 : 445-454, 2018

      23 Rødgaard JC, "Merkel cell carcinoma : a single-centre experience" 37 : 417-422, 2014

      24 Cirillo F, "Merkel cell carcinoma : a retrospective study on 48 cases and review of literature" 2012 : 749030-, 2012

      25 Dancey AL, "Merkel cell carcinoma : a report of 34 cases and literature review" 59 : 1294-1299, 2006

      26 Koljonen V, "Merkel cell carcinoma : a clinicopathological study of 34 patients" 29 : 607-610, 2003

      27 Ratner D, "Merkel cell carcinoma" 29 : 143-156, 1993

      28 Youlden DR, "Incidence and survival for Merkel cell carcinoma in Queensland, Australia, 1993-2010" 150 : 864-872, 2014

      29 Moll R, "Identification of Merkel cells in human skin by specific cytokeratin antibodies : changes of cell density and distribution in fetal and adult plantar epidermis" 28 : 136-154, 1984

      30 Moll I, "Human Merkel cells--aspects of cell biology, distribution and functions" 84 : 259-271, 2005

      31 Agelli M, "Epidemiology of primary Merkel cell carcinoma in the United States" 49 : 832-841, 2003

      32 Robertson JP, "Epidemiology of Merkel cell carcinoma in New Zealand : a population-based study" 173 : 835-837, 2015

      33 Asgari MM, "Effect of host, tumor, diagnostic, and treatment variables on outcomes in a large cohort with Merkel cell carcinoma" 150 : 716-723, 2014

      34 Fitzgerald TL, "Dramatic increase in the incidence and mortality from Merkel cell carcinoma in the United States" 81 : 802-806, 2015

      35 Rekhi B, "Clinicopathological spectrum of a series of Merkel cell carcinomas diagnosed at a tertiary cancer referral center in India, with current concepts" 19 : 341-346, 2015

      36 Heath M, "Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients : the AEIOU features" 58 : 375-381, 2008

      37 Higaki-Mori H, "Association of Merkel cell polyomavirus infection with clinicopathological differences in Merkel cell carcinoma" 43 : 2282-2291, 2012

      38 Lacour JP, "Anatomical mapping of Merkel cells in normal human adult epidermis" 125 : 535-542, 1991

      39 Harms KL, "Analysis of prognostic factors from 9387 Merkel cell carcinoma cases forms the basis for the new 8th edition AJCC staging system" 23 : 3564-3571, 2016

      40 Viscidi RP, "Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus" 18 : 1737-1743, 2011

      41 Açıkalın A, "A unique case of merkel cell carcinoma with ovarian metastasis" 31 : 356-359, 2014

      42 오승일, "8례의 메켈세포암종의 후향적 연구" 대한두개안면성형외과학회 14 (14): 41-45, 2013

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      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2009-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2007-01-01 평가 SCOPUS 등재 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 1.11 0.23 0.72
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.67 0.48 0.376 0.03
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