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      KCI등재후보

      골반골절 환자의 골절위치와 출혈량간의 상관관계 분석을 통한 대량수혈 필요에 대한 간단한 예측도구 개발: 골반골 출혈 지수 = Qriginal Article : Development of Simple Prediction Method for Injury Severity and Amount of Traumatic Hemorrhage via Analysis of the Correlation between Site of Pelvic Bone Fracture and Amount of Transfusion: Pelvic Bleeding Score

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      https://www.riss.kr/link?id=A99595110

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      다국어 초록 (Multilingual Abstract)

      Purpose: Hypovolemic shock is the leading cause of death in multiple trauma patients with pelvic bone fracures. The purpose of this study was to develop a simple prediction method for injury severity and amount of hemorrhage via an analysis of the cor...

      Purpose: Hypovolemic shock is the leading cause of death in multiple trauma patients with pelvic bone fracures. The purpose of this study was to develop a simple prediction method for injury severity and amount of hemorrhage via an analysis of the correlation between the site of pelvic bone fracture and the amount of transfusion and to verify the usefulness of the such a simple scoring system. Methods: We analyzed retrospectively the medical records and radiologic examination of 102 patients who had been diagnosed as having a pelvic bone fracture and who had visited the Emergency Department between January 2007 and December 2011. Fracture sites in the pelvis were confirmed and re-classified anatomically as pubis, ilium or sacrum. A multiple linear regression analysis was performed on the amount of transfusion, and a simplified scoring system was developed. The predictive value of the amount of transfusion for the scoring system as verified by using the receiver operating characteristics (ROC). The area under the curve of the ROC was compared with the injury severity score (ISS). Results: From among the 102 patients, 97 patients (M:F=68:29, mean age=46.7±16.6 years) were enrolled for analysis. The average ISS of the patients was 16.2±7.9, and the average amount of packed RBC transfusion for 24 hr was 3.9±4.6 units. The regression equation resulting from the multiple linear regression analysis was ``packed RBC units=1.40×(sacrum fracture)+1.72×(pubis fracture)+1.67×(ilium fracture)+0.36`` and was found to be suitable (p=0.005). We simplified the regression equation to ``Pelvic Bleeding Score=sacrum+pubis +ilium``. Each fractured site was scored as 0(no fracture) point, 1(right or left) point, or 2(both) points. Sacrum had only 0 or 1 point. The score ranged from 0 to 5. The area under the curve (AUC) of the ROC was 0.718 (95% CI: 0.588-0.848, p=0.009). For an upper Pelvis Bleeding Score of 3 points, the sensitivity of the prediction for a massive transfusion was 71.4%, and the specificity was 69.9%. Conclusion: We developed a simplified scoring system for the anatomical fracture sites in the pelvis to predict the requirement for a transfusion (Pelvis Bleeding Score (PBS)). The PBS, compared with the ISS, is considered a useful predictor of the need for a transfusion during initial management. (J Trauma Inj 2012;25:139-144)

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      참고문헌 (Reference)

      1 송경환, "혈역학적으로 불안정한 골반골 골절이 동반된 외상환자에서 사망 예측 인자" 대한응급의학회 20 (20): 280-287, 2009

      2 Theodore M, "Young-Burgess Classification of pelvic ring fractures: does it predict mortality, transfusion requirements, and non-orthopaedic Injuries?" 24 : 603-609, 2010

      3 Robert AM, "Predicting blood loss in isolated pelvic and acetabular high-energy trauma" 21 : 603-607, 2007

      4 Blackmore CC, "Predicting Major Hemorrhage in Patients with Pelvic Fracture" 61 : 346-352, 2006

      5 Burgees Ar., "Pelvic ring disruptions : effective classification system and treatment protocols" 30 : 848-856, 1990

      6 S.J. Slater, "Pelvic fractures-A guide to classification and management" 74 : 16-23, 2010

      7 Evers BM, "Pelvic fracture hemorrhage. Priorities in management" 124 : 442-444, 1989

      8 Suk SI, "ORTHOPAEDICS. 6th ed" Choishin Medicine Publisher 1006-, 2006

      9 Young JWR, "Lateral compression fracture of the pelvis: The importance of plain radiographs for diagnosis and surgical management" 15 : 103-104, 1986

      10 Moreno C, "Hmeorrhage associated with major pelvic fracture: a multi speciality challenge" 26 : 987-994, 1986

      1 송경환, "혈역학적으로 불안정한 골반골 골절이 동반된 외상환자에서 사망 예측 인자" 대한응급의학회 20 (20): 280-287, 2009

      2 Theodore M, "Young-Burgess Classification of pelvic ring fractures: does it predict mortality, transfusion requirements, and non-orthopaedic Injuries?" 24 : 603-609, 2010

      3 Robert AM, "Predicting blood loss in isolated pelvic and acetabular high-energy trauma" 21 : 603-607, 2007

      4 Blackmore CC, "Predicting Major Hemorrhage in Patients with Pelvic Fracture" 61 : 346-352, 2006

      5 Burgees Ar., "Pelvic ring disruptions : effective classification system and treatment protocols" 30 : 848-856, 1990

      6 S.J. Slater, "Pelvic fractures-A guide to classification and management" 74 : 16-23, 2010

      7 Evers BM, "Pelvic fracture hemorrhage. Priorities in management" 124 : 442-444, 1989

      8 Suk SI, "ORTHOPAEDICS. 6th ed" Choishin Medicine Publisher 1006-, 2006

      9 Young JWR, "Lateral compression fracture of the pelvis: The importance of plain radiographs for diagnosis and surgical management" 15 : 103-104, 1986

      10 Moreno C, "Hmeorrhage associated with major pelvic fracture: a multi speciality challenge" 26 : 987-994, 1986

      11 Jr. PM, "Hemorrhage in major pelvic fracture" 68 : 757-773, 1988

      12 Christopher EW, "Haemodynamically unstable pelvic fractures" 40 : 1023-1030, 2009

      13 Slatis P, "External fixation of unstable pelvic fracture" 171 : 73-80, 1980

      14 Smith W, "Early predictors of mortality in hemodynamically unstable pelvis fractures" 21 : 31-37, 2007

      15 Peltier LF, "Complications associated with fractures of the pelvis" 47 : 1060-1069, 1965

      16 Cheon YJ, "Clinical patterns of pelvic fracture at the emergency department" 16 : 43-49, 2003

      17 Gabbe BJ, "Cameron PA. Predictors of mortality following severe pelvic ring fracture: Results of a populationbased study" 42 : 985-991, 2011

      18 Lunsjo K, "Associated injuries and not fracture instability predict mortality in pelvic fracture: a prospective study of 100 patients" 62 : 687-692, 2007

      19 Blackmore CC, "Assessment of volume of hemorrhage and outcome from pelvic fractures" 138 : 504-509, 2003

      20 Sarikcioglu L, "Anastomotic vessels in the retropubic region: Corona mortis" 62 : 179-182, 2003

      21 Mucha PJ, "Analysis of pelvic fracture management" 24 : 386-387, 1984

      22 "American College of Surgeons, In Advanced Trauma Life Support for Doctors (student course manual). 8th ed" American College of Surgeons on Trauma 61-, 2008

      23 Kim SJ, "A clinical study of the pelvic bone fracture" 26 : 1441-1449, 1991

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