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    조영제 유발 급성 신손상에 대한 장기임상 추적 관찰 및 예후

    한글로보기

    https://www.riss.kr/link?id=T15777134

    • 저자
    • 발행사항

      전주: 전북대학교 일반대학원, 2021

    • 학위논문사항

      학위논문(석사) -- 전북대학교 일반대학원 , 의학과 , 2021. 2

    • 발행연도

      2021

    • 작성언어

      영어

    • 주제어
    • 발행국(도시)

      전북특별자치도

    • 기타서명

      Long Term Clinical Follow-up and Prognosis for Contrast-Induced Acute Kidney Injury

    • 형태사항

      iv, 25 p.; 26 cm.

    • 일반주기명

      전북대학교 논문은 저작권에 의해 보호받습니다.
      지도교수: 이상록
      참고문헌 : p. 19-23

    • UCI식별코드

      I804:45011-000000052425

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    부가정보

    다국어 초록 (Multilingual Abstract) kakao i 다국어 번역

    영어
    한국어
    Background: The development of Contrast-induced acute kidney injury (CI-AKI) was related to short-term poor prognosis. The aim of our study was to evaluate the long-term outcome of CI-AKI during 10-year follow-up.
    Subjects and Methods: We enrolled 383 patients (mean follow up 121±46 months) who received coronary intervention in Jeonbuk National University Hospital (South Korea, Jeonju) from January 2006 to December 2006. We excluded the cardiogenic shock and end-stage renal disease patients who requiring regular dialysis before study enrollment. For Coronary Angiography (CAG), we administered iodixanol as contrast media in all patients. The primary study endpoints were defined by all-cause death and the secondary key study endpoints were defined by major adverse cardiac events (MACE) including cardiac death, non-fatal myocardial infarction (MI), and target vessel revascularization (TVR) at 1, 5, and 10-year.
    Results: The study population was divided into two groups: group I (non-CI-AKI, n= 360, 61.7±11.2 years, male 62.5%) and group II (CI-AKI, n=23, 66.7±9.5 years, male 56.5%). Baseline clinical characteristics were not different between the two groups. All-cause death at 1-year (3.0% vs 13.0%), 5-year (16.4% vs 30.4%), and 10-year (22.2% vs 52.2%) were higher in group CI-AKI. MACE at 1,5,10-year was not significantly different between the two groups(p=0.073). Multivariate Cox regression analysis showed CI-AKI (HR 2.114, 95% CI 1.15 – 3.90, p=0.017) was an independent predictor for 10-year all-cause death.
    Conclusion: The poor prognosis of CI-AKI was persistently observed after 10-year clinical follow-up. Future larger studies would be needed to clarify our results.
    번역하기

    Background: The development of Contrast-induced acute kidney injury (CI-AKI) was related to short-term poor prognosis. The aim of our study was to evaluate the long-term outcome of CI-AKI during 10-year follow-up. Subjects and Methods: We enrolled 383...

    Background: The development of Contrast-induced acute kidney injury (CI-AKI) was related to short-term poor prognosis. The aim of our study was to evaluate the long-term outcome of CI-AKI during 10-year follow-up.
    Subjects and Methods: We enrolled 383 patients (mean follow up 121±46 months) who received coronary intervention in Jeonbuk National University Hospital (South Korea, Jeonju) from January 2006 to December 2006. We excluded the cardiogenic shock and end-stage renal disease patients who requiring regular dialysis before study enrollment. For Coronary Angiography (CAG), we administered iodixanol as contrast media in all patients. The primary study endpoints were defined by all-cause death and the secondary key study endpoints were defined by major adverse cardiac events (MACE) including cardiac death, non-fatal myocardial infarction (MI), and target vessel revascularization (TVR) at 1, 5, and 10-year.
    Results: The study population was divided into two groups: group I (non-CI-AKI, n= 360, 61.7±11.2 years, male 62.5%) and group II (CI-AKI, n=23, 66.7±9.5 years, male 56.5%). Baseline clinical characteristics were not different between the two groups. All-cause death at 1-year (3.0% vs 13.0%), 5-year (16.4% vs 30.4%), and 10-year (22.2% vs 52.2%) were higher in group CI-AKI. MACE at 1,5,10-year was not significantly different between the two groups(p=0.073). Multivariate Cox regression analysis showed CI-AKI (HR 2.114, 95% CI 1.15 – 3.90, p=0.017) was an independent predictor for 10-year all-cause death.
    Conclusion: The poor prognosis of CI-AKI was persistently observed after 10-year clinical follow-up. Future larger studies would be needed to clarify our results.

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    목차 (Table of Contents)

    • LIST OF FIGURES I
    • LIST OF TABLES II
    • ABSTRACT III
    • INTRODUCTION 1
    • METHODS AND METHODS 3
    • LIST OF FIGURES I
    • LIST OF TABLES II
    • ABSTRACT III
    • INTRODUCTION 1
    • METHODS AND METHODS 3
    • RESULTS 7
    • DISCUSSION 9
    • CONCLUSIONS 13
    • FIGURES 14
    • TABLES 15
    • REFERENCES 19
    • 국 문 요 약 24
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