국내 암환자의 오심구토에 적용한 비약물적 중재효과의 메타분석 = A Meta-Analysis of Intervention Studies on Nausea and Vomiting in Cancer Patients

다국어 초록 (Multilingual Abstract)

This study was designed to analyze the characteristics and effect size of published intervention studies related to nausea & vomiting among cancer patients. Methods: A total of 1,083 studies were retrieved. From these studies, 20 studies met the inclusion criteria with a total of 698 participants. Two authors independently extracted data from the selected studies and assessed the methodological quality. The data were analyzed by the RevMan 5.0 program of Cochrane library. Results: The twenty studies utilized various non-pharmacological interventions:Nine studies on acupuncture (45%), Five studies utilized massage (25%), Two studies used oral cryotherapy (10%) and Four studies used other therapies. In the twenty studies the effect size of the intervention studies reported a higher effect sizes for massage (d=-1.62) and acupuncture (d=-0.89). Conclusion: This study suggests that non-drug therapy can reduce the levels of nausea and vomiting intensity. Massage and acupuncture interventions studies were more numerous and this may account for the higher effect rate.

참고문헌 (Reference)

1 정복례, "종양간호학회지 논문 내용과 경향 분석 -창간호에서 2007년까지" 대한종양간호학회 8 (8): 61-66, 2008

2 김은주, "말기 암 환자에게 적용한 발 반사 마사지의 통증경감 및 수면증진 효과" 병원간호사회 14 (14): 33-44, 2008

3 오복자(Oh, Pok-Ja), "국내 종양간호연구의 분석: 2003-2008" 대한종양간호학회 10 (10): 80-87, 2010

4 Cohen, J., "Statistical power analysis for the behavioral science (2nd ed)" Lawrence Erlbaum Associate 1988

5 Tipton, J. M., "Putting evidence into practice: Evidence-based interventions to prevent, manage, and treat chemotherapy-induced nausea and vomiting" 11 (11): 69-78, 2007

6 Dundee, J. W., "Prolongation of the antiemetic action of P6 acupuncture by acupressure in patients having cancer chemotherapy" 83 (83): 360-362, 1990

7 Korean Society Pharmacoepidemiology and Risk Management, "Pharmacoepidemiology" Seoul National University Press 2011

8 Dundee, J. W., "Non-invasive stimulation of the P6 (Neiguan) antiemetic acupuncture point in cancer chemotherapy" 84 (84): 210-212, 1991

9 Choi, J. K., "Meta-analysis of the effectiveness of nursing treatment on nausea․vomiting, anxiety, and fatigue in cancer patients treated by chemotherapy" Chonnam National University 2007

10 Song, H. H., "Meta-analysis of medical, nursing, social science study" Chungmoon Publishing 2006

11 Park, S. W., "Meta-analysis nursing interventions effectiveness for symptom management of cancer patients" Korea University 2007

12 Cochrane, "Meta-Analysis program"

13 Kim, D. W., "Introduction of cancer treatment" 2009

14 Snyder, M., "Independent nursing interventions (2nd ed.)" Delmai Publishers 1992

15 Neymark, N., "Impact of emesis on clinical and economic outcomes of cancer therapy with highly emetogenic chemotherapy regimens: A retrospective analysis of three clinical trials" 13 (13): 812-818, 2005

16 Snyder, M., "Efficacy of hand massage in decreasing agitation behaviors associated with care activities in persons with dementia" 16 (16): 60-63, 1995

17 Rehse, B., "Effects of psychological interventions on quality of life in adult cancer patients: Meta analysis of 37 published controlled outcome studies" 50 (50): 179-186, 2003

18 Bender, C. M., "Chemotherapy-induced nausea and vomiting" 6 (6): 94-102, 2002

19 Ezzo, J. M., "Acupuncture-point stimulation for chemotherapy-induced nausea or vomiting (review)"

20 Min, Y. C., "A meta-analysis of intervention studies applied to pain of cancer patients" Sahmyook University 2011