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      KCI등재후보 SCOPUS

      An Assessment of Thoracic Inlet Heart Score in Maltese Dogs with ACVIM Stage B Myxomatous Mitral Valve Disease

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      https://www.riss.kr/link?id=A109357842

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      Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. Vertebral heart score (VHS) is used for the diagnosis, treatment, and monitoring of MMVD, and it is one of the criteria used to distinguish between stages B1 and B2 according to the American College of Veterinary Internal Medicine (ACVIM) guidelines. The thoracic inlet heart score (TIHS) method is simple to perform and provides practitioners with an additional tool for evaluating dogs with clinical signs compatible with MMVD stage B. Previous studies have evaluated TIHS. In our study, we assessed correlations of TIHS with other radiographic and echocardiographic indices in Maltese dogs with MMVD stages B1 and B2. Eighty-seven Maltese dogs with MMVD stage B1 or B2, which visited Chungnam National University Veterinary Medicine Teaching Hospital, were included in this study. Each dog was diagnosed with MMVD ACVIM stage B1 or B2 through physical examination, cardiac auscultation, thoracic radiography, and echocardiography, with evaluation of TIHS, VHS, vertebral left atrial size (VLAS), left atrial to the aotic root ratio (LA:Ao ratio), and left ventricular internal diameter in diastole, normalized for body weight (LVIDDn). TIHS increased as the disease progressed and showed a significant difference between stages B1 and B2. Furthermore, TIHS positively correlated with VHS, LA:Ao ratio, and LVIDDn. The correlation coefficients revealed the strongest significant correlations between TIHS and VHS. In conclusion, TIHS can help diagnose and monitor MMVD in Maltese dogs, in addition to measuring VHS.
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      Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. Vertebral heart score (VHS) is used for the diagnosis, treatment, and monitoring of MMVD, and it is one of the criteria used to distinguish between stages B1 and B2 acc...

      Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. Vertebral heart score (VHS) is used for the diagnosis, treatment, and monitoring of MMVD, and it is one of the criteria used to distinguish between stages B1 and B2 according to the American College of Veterinary Internal Medicine (ACVIM) guidelines. The thoracic inlet heart score (TIHS) method is simple to perform and provides practitioners with an additional tool for evaluating dogs with clinical signs compatible with MMVD stage B. Previous studies have evaluated TIHS. In our study, we assessed correlations of TIHS with other radiographic and echocardiographic indices in Maltese dogs with MMVD stages B1 and B2. Eighty-seven Maltese dogs with MMVD stage B1 or B2, which visited Chungnam National University Veterinary Medicine Teaching Hospital, were included in this study. Each dog was diagnosed with MMVD ACVIM stage B1 or B2 through physical examination, cardiac auscultation, thoracic radiography, and echocardiography, with evaluation of TIHS, VHS, vertebral left atrial size (VLAS), left atrial to the aotic root ratio (LA:Ao ratio), and left ventricular internal diameter in diastole, normalized for body weight (LVIDDn). TIHS increased as the disease progressed and showed a significant difference between stages B1 and B2. Furthermore, TIHS positively correlated with VHS, LA:Ao ratio, and LVIDDn. The correlation coefficients revealed the strongest significant correlations between TIHS and VHS. In conclusion, TIHS can help diagnose and monitor MMVD in Maltese dogs, in addition to measuring VHS.

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      참고문헌 (Reference)

      1 Buchanan JW, "Vertebral scale system to measure canine heart size in radiographs" 206 : 194-199, 1995

      2 Jepsen-Grant K, "Vertebral heart scores in eight dog breeds" 54 : 3-8, 2013

      3 Marbella Fernández D, "The thoracic inlet length as a reference point to radiographically assess cardiac enlargement in dogs with myxomatous mitral valve disease" 13 : 2666-, 2023

      4 Marbella Fernández D, "The thoracic inlet heart size, a new approach to radiographic cardiac measurement" 13 : 389-, 2023

      5 Lam C, "Radiographic quantification of left atrial size in dogs with myxomatous mitral valve disease" 35 : 747-754, 2021

      6 Lord PF, "Radiographic heart size and its rate of increase as tests for onset of congestive heart failure in Cavalier King Charles Spaniels with mitral valve regurgitation" 25 : 1312-1919, 2011

      7 Fox PR, "Pathology of myxomatous mitral valve disease in the dog" 14 : 103-126, 2012

      8 Höllmer M, "Left atrial volume and function in dogs with naturally occurring myxomatous mitral valve disease" 19 : 24-34, 2017

      9 Hansson K, "Interobserver variability of vertebral heart size measurements in dogs with normal and enlarged hearts" 46 : 122-130, 2005

      10 이창민 ; 송두원 ; 노웅빈 ; 강민희 ; 박희명, "Genome-wide association study of degenerative mitral valve disease in Maltese dogs" 20 : 63-71, 2019

      1 Buchanan JW, "Vertebral scale system to measure canine heart size in radiographs" 206 : 194-199, 1995

      2 Jepsen-Grant K, "Vertebral heart scores in eight dog breeds" 54 : 3-8, 2013

      3 Marbella Fernández D, "The thoracic inlet length as a reference point to radiographically assess cardiac enlargement in dogs with myxomatous mitral valve disease" 13 : 2666-, 2023

      4 Marbella Fernández D, "The thoracic inlet heart size, a new approach to radiographic cardiac measurement" 13 : 389-, 2023

      5 Lam C, "Radiographic quantification of left atrial size in dogs with myxomatous mitral valve disease" 35 : 747-754, 2021

      6 Lord PF, "Radiographic heart size and its rate of increase as tests for onset of congestive heart failure in Cavalier King Charles Spaniels with mitral valve regurgitation" 25 : 1312-1919, 2011

      7 Fox PR, "Pathology of myxomatous mitral valve disease in the dog" 14 : 103-126, 2012

      8 Höllmer M, "Left atrial volume and function in dogs with naturally occurring myxomatous mitral valve disease" 19 : 24-34, 2017

      9 Hansson K, "Interobserver variability of vertebral heart size measurements in dogs with normal and enlarged hearts" 46 : 122-130, 2005

      10 이창민 ; 송두원 ; 노웅빈 ; 강민희 ; 박희명, "Genome-wide association study of degenerative mitral valve disease in Maltese dogs" 20 : 63-71, 2019

      11 Malcolm EL, "Diagnostic value of vertebral left atrial size as determined from thoracic radiographs for assessment of left atrial size in dogs with myxomatous mitral valve disease" 253 : 1038-1045, 2018

      12 Keene BW, "ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs" 33 : 1127-1140, 2019

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