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      미숙아에서 선별검사를 이용한 발달지연 위험인자 분석 = Analysis of Risk Factors for Developmental Delay in Preterm Infants Using Screening Test

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      https://www.riss.kr/link?id=A105608321

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      다국어 초록 (Multilingual Abstract)

      Purpose: The purpose of this study was to identify the risk factors for developmental delays in preterm infants. Methods: We studied 151 preterm infants admitted to the neonatal intensive care unit (NICU) at the Hallym University Kangnam Sacred Heart Hospital from January 2013 to November 2016. After discharge, the infants were evaluated by a pediatric neurologist via the developmental screening test K-ASQ:SE II, which consists of five domains: communication (CC), gross motor (GM), fine motor (FM), problem solving (PS), and social-emotional (SE). The subjects were divided into a normal group and an abnormal group (abnormal results on at least one of the five domains). Several variables were compared between the two groups and risk factors for developmental delays were analyzed. Results: Several factors, such as birth weight (BW), gestational age (GA), Apgar score at 1 and 5 min (AS1, AS5), hospital days (HDs), respiratory distress syndrome (RDS), chronic lung diseases, intraventricular hemorrhage (IVH), early sepsis, retinopathy of prematurity (ROP), and history of management of invasive ventilators, dexamethasone, anti-hypotensive, were significantly different between the normal and abnormal groups. BW was a risk factor for developmental delay according to the binary logistic regression analysis. On individual domain analysis, risk factors were lower GA for domains CC and FM, lower AS1 for GM domain, lower BW for PS domain, and longer HDs for SE domain. Conclusion: In preterm infants, regular developmental screening especially follow-up observation, is important for early detection of developmental delay, considering the risk factors, such as GA (≤30 weeks), BW (≤1,500 g), low AS1, and long HDs, which may be helpful in the early diagnosis of developmental delay.
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      Purpose: The purpose of this study was to identify the risk factors for developmental delays in preterm infants. Methods: We studied 151 preterm infants admitted to the neonatal intensive care unit (NICU) at the Hallym University Kangnam Sacred Heart ...

      Purpose: The purpose of this study was to identify the risk factors for developmental delays in preterm infants. Methods: We studied 151 preterm infants admitted to the neonatal intensive care unit (NICU) at the Hallym University Kangnam Sacred Heart Hospital from January 2013 to November 2016. After discharge, the infants were evaluated by a pediatric neurologist via the developmental screening test K-ASQ:SE II, which consists of five domains: communication (CC), gross motor (GM), fine motor (FM), problem solving (PS), and social-emotional (SE). The subjects were divided into a normal group and an abnormal group (abnormal results on at least one of the five domains). Several variables were compared between the two groups and risk factors for developmental delays were analyzed. Results: Several factors, such as birth weight (BW), gestational age (GA), Apgar score at 1 and 5 min (AS1, AS5), hospital days (HDs), respiratory distress syndrome (RDS), chronic lung diseases, intraventricular hemorrhage (IVH), early sepsis, retinopathy of prematurity (ROP), and history of management of invasive ventilators, dexamethasone, anti-hypotensive, were significantly different between the normal and abnormal groups. BW was a risk factor for developmental delay according to the binary logistic regression analysis. On individual domain analysis, risk factors were lower GA for domains CC and FM, lower AS1 for GM domain, lower BW for PS domain, and longer HDs for SE domain. Conclusion: In preterm infants, regular developmental screening especially follow-up observation, is important for early detection of developmental delay, considering the risk factors, such as GA (≤30 weeks), BW (≤1,500 g), low AS1, and long HDs, which may be helpful in the early diagnosis of developmental delay.

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      목차 (Table of Contents)

      • 서론
      • 대상 및 방법
      • 결과
      • 고찰
      • 요약
      • 서론
      • 대상 및 방법
      • 결과
      • 고찰
      • 요약
      • References
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      참고문헌 (Reference)

      1 허영희, "한국 신생아집중치료실 입원 신생아의 임신나이별 생존율의 변화 (2002-2009년)" 대한신생아학회 19 (19): 134-139, 2012

      2 이세규, "최근 10년간 1,500 g이하 극소 저출생 체중아의 신경학적 위험 요인 및 예후 변화에 관하여" 대한소아과학회 49 (49): 1050-1055, 2006

      3 이서윤, "조산아의 저출생체중과 연령이 학령전기 인지수행에 미치는 영향" 대한소아청소년 정신의학회 28 (28): 141-148, 2017

      4 천미경, "극소 저체중 출생아에서 뇌실 내 출혈의 중증도 관련 위험 요인과 신경발달학적 예후" 대한주산의학회 25 (25): 266-275, 2014

      5 우미경, "고위험 신생아에서 Bayley 발달 검사 결과에 영향을 미치는 신경발달 예후인자에 대한 연구" 대한소아과학회 52 (52): 1221-1227, 2009

      6 Kang JW, "Prognostic factors of developmental delay in premature infants" 15 : 67-74, 2007

      7 Valla L, "Prevalence of suspected developmental delays in early infancy: results from a regional population-based longitudinal study" 15 : 215-, 2015

      8 Sutton PS, "Preterm birth and neurodevelopment: a review of outcomes and recommendations for early identification and cost-effective interventions" 59 : 258-265, 2013

      9 Institute of Medicine, Board on Health Sciences Policy, "Preterm Birth: Causes, Consequences, and Prevention" NAP 313-345, 2007

      10 Tsai AJ, "Predictors of neurodevelopmental outcomes in preterm infants with intraparenchymal hemorrhage" 34 : 399-404, 2014

      1 허영희, "한국 신생아집중치료실 입원 신생아의 임신나이별 생존율의 변화 (2002-2009년)" 대한신생아학회 19 (19): 134-139, 2012

      2 이세규, "최근 10년간 1,500 g이하 극소 저출생 체중아의 신경학적 위험 요인 및 예후 변화에 관하여" 대한소아과학회 49 (49): 1050-1055, 2006

      3 이서윤, "조산아의 저출생체중과 연령이 학령전기 인지수행에 미치는 영향" 대한소아청소년 정신의학회 28 (28): 141-148, 2017

      4 천미경, "극소 저체중 출생아에서 뇌실 내 출혈의 중증도 관련 위험 요인과 신경발달학적 예후" 대한주산의학회 25 (25): 266-275, 2014

      5 우미경, "고위험 신생아에서 Bayley 발달 검사 결과에 영향을 미치는 신경발달 예후인자에 대한 연구" 대한소아과학회 52 (52): 1221-1227, 2009

      6 Kang JW, "Prognostic factors of developmental delay in premature infants" 15 : 67-74, 2007

      7 Valla L, "Prevalence of suspected developmental delays in early infancy: results from a regional population-based longitudinal study" 15 : 215-, 2015

      8 Sutton PS, "Preterm birth and neurodevelopment: a review of outcomes and recommendations for early identification and cost-effective interventions" 59 : 258-265, 2013

      9 Institute of Medicine, Board on Health Sciences Policy, "Preterm Birth: Causes, Consequences, and Prevention" NAP 313-345, 2007

      10 Tsai AJ, "Predictors of neurodevelopmental outcomes in preterm infants with intraparenchymal hemorrhage" 34 : 399-404, 2014

      11 Chang YS, "Past, present, and future of neonatology in Korea" 59 (59): 487-489, 2016

      12 Hack M, "Outcomes of children of extremely low birthweight and gestational age in the1990s" 5 : 89-106, 2000

      13 Stool BJ, "Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection" 292 : 2357-2365, 2004

      14 Vohr BR, "Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994" 105 : 1216-1226, 2000

      15 Hack M, "Neurodevelopment and predictors of outcomes of children with birth weight of less than 1000 g: 1992-1995" 154 : 725-731, 2000

      16 Stoll BJ, "Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network" 126 : 443-456, 2010

      17 Rand KM, "Neonatal infection and later neurodevelopmental risk in the very preterm infant" 170 : 97-104, 2016

      18 Marret S, "Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation" 110 : 72-80, 2007

      19 Hughes AJ, "Motor development interventions for preterm infants: a systematic review and metaanalysis" 138 : e20160147-, 2016

      20 Aly H, "Is mechanical ventilation associated with intraventricular hemorrhage in preterm infants?" 34 : 201-205, 2012

      21 Szpecht D, "Intraventricular hemorrhage in neonates born from 23 to 26 weeks of gestation: retrospective analysis of risk factors" 26 : 89-94, 2017

      22 Bolisetty S, "Intraventricular hemorrhage and neurodevelopmental outcomes in extreme preterm infants" 133 : 55-62, 2014

      23 Jin EK, "Impact of perinatal risk factors on mental or psychomotor developmental outcome of very low birth weight infants" 40 : 1202-1209, 1997

      24 Schonhaut L, "Gestational age and developmental risk in moderately and late preterm and early term infants" 135 : e835-e841, 2015

      25 Cioni G, "Early intervention in neurodevelopmental disorders: underlying neural mechanisms" 58 (58): 61-66, 2016

      26 Batton B, "Early blood pressure, antihypotensive therapy and outcomes at 18-22 months' corrected age in extremely preterm infants" 101 : F201-F206, 2016

      27 Torabi F, "Correlation between high-risk pregnancy and developmental delay in children aged 4-60 months" 7 : 18811-, 2012

      28 Furekawa S, "Circulatory disturbances during the first postnatal 24 hours in extremely premature infants 25 weeks or less of gestation with histological fetal inflammation" 34 : 27-33, 2008

      29 Shim JW, "Changes in survival rate for very-lowbirth-weight infants in Korea: comparison with other countries" 30 : S25-S34, 2015

      30 Cheong JL, "Association between moderate and late preterm birth and neurodevelopment and social-emotional development at age 2 years" 171 : e164805-, 2017

      31 Been JV, "Antenatal steroids and neonatal outcome after chorioamnionitis: a meta-analysis" 118 : 113-122, 2011

      32 Xiong T, "An overview of risk factors for poor neurodevelopmental outcome associated with prematurity" 8 : 293-300, 2012

      33 Als H, "A three-center, randomized, controlled trial of individualized developmental care for very low birth weight preterm infants: medical, neurodevelopmental, parenting, and caregiving effects" 24 : 399-408, 2003

      34 Singer L, "A longitudinal study of developmental outcome of infants with bronchopulmonary dysplasia and very low birth weight" 100 : 987-993, 1997

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2019 평가예정 신규평가 신청대상 (신규평가)
      2018-12-01 평가 등재후보 탈락 (계속평가)
      2016-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      2012-01-01 평가 등재후보 탈락 (등재후보1차)
      2010-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2008-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.17 0.17 0.17
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.16 0.14 0.384 0.02
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