자궁경부암 진단 방법에서 New Cervicography의 유용성 = New Cervicography in the Diagnosis of Cervical Cancer

다국어 초록 (Multilingual Abstract)

New Cervicography, a Pap smear adjunct test, is an innovative cervical cancer surveillance system. It is a relatively new technique in which a photograph of the cervix is obtained without the aid of colposcope after application of 5% acetic acid.
The purpose of this study was to investigate the role of New Cervicography in diagnosis of cervical cancer. Pap smear and cervicogram data were obtained from 143 patients who visited the Department of Obstetrics and Gynecology, Chungnam National University Hospital from September 1996 to May 1997. Histologic specimens were obtained from patients in whom abnormalities were detected by either Pap smear or cervicogram. Specimens were taken either by colposcopically directed biopsy or large loop excision af the transformation zone.
Results were as follows :
1. Pap smear results were normal in 63 cases(44.0%), ASCUS(atypical squamous cells of undermined significance) in 14 cases(9.8%), and abnormal(above low grade squamous intraepithelial lesion) in 66 cases(46.2%).
2. New Cervicographic findings were negative in 45 cases(31.5%), benign or suspicious atypical in 24 cases(16.8%), and positive in 74 cases(51.7%).
3. The sensitivity(86.7% vs 71.1%, p$lt;0.01), specificity(96.7% vs 88.3%, p$lt;0.05), and negative predictive value(84.1% vs 68.8%, p$lt;0.05) of New Cervicography were significantly higher than for Pap smear. The false negative rate(13.3% vs 28.9%, p$lt;0.01) and the false positive rate(3.3% vs 11.7%, p$lt;0.05) of New Cervicography were significantly lower than for Pap smear.
4. When New Cervicography and Pap smear were used together, the sensitive was higher than for Pap smear used alone(p$lt;0.01) and the specificity was higher than for New Cervicography used alone(p$lt;0.01).
5. The ASCUS in Pap smear was 9.8%. Appropriate diagnostic modalities, such as New Cervicography or cervical biopsy are necessary for detecting more serious lesions of the cervix.
New Cervicograohy is an important tool for detecting cervical cancer. When cervicograms are used in conjunction with Pap smear, the detection rate of cervical cancer is improved.