This study was carried out to investigate the effect of chromium picolinate supplementation on the metabolism of rats. Male Sprague-Dawley rats were divided into 3 groups and each group had 16 rats. Three experimental diets of CT(control), HS(high suc...
This study was carried out to investigate the effect of chromium picolinate supplementation on the metabolism of rats. Male Sprague-Dawley rats were divided into 3 groups and each group had 16 rats. Three experimental diets of CT(control), HS(high sucrose) and HF(high fat) were fed for 10 weeks and then chromium picolinate were supplemented to HS and HF groups for 6 weeks. Eight rats from each group were sacrificed after 10 weeks and another 8 rats from each group were sacrificed after 16 weeks. The results from this experiment were summarized as follows: The change of calorie intake and body weight was not significantly different among three groups after chromium picolinate supplementation. The plasma glucose and insulin concentration in CT group tended to increase after 16 weeks but those in HS and HF groups tended to decrease after chromium picolinate supplementation. The plasma triglyceride and cholesterol concentration of CT group tended to be higher than those of HS and HF groups which were supplemented by chromium picolinate. Our results indicate that chromium picolinate tend to reduce blood glucose, insulin, triglyceride, and cholesterol level but increase HDL-cholesterol level.