1 Shin DM, "p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma" 88 : 519-529, 1996
2 Chang X, "dentification of hypermethylated genes associated with cisplatin resistance in human cancers" 1 (1): 2870-2879, 2010
3 Rosin MP, "Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia" 6 : 357-, 2000
4 Folkman J, "Tumor angiogenesis: therapeutic implications" 18 (18): 1182-1186, 1971
5 Field JK, "The role of the p53 tumor suppressor gene in squamous cell carcinoma of the head and neck" 119 : 1118-1122, 1993
6 Xie X, "The prognostic value of spontaneous apoptosis. Bax, Bcl- 2, and p53 in oral squamous cell carcinoma of the tongue" 86 : 913-920, 1999
7 Partridge M, "The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer" 79 : 1821-1827, 1999
8 Strome SE, "Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations" 8 : 1093-1100, 2002
9 Liggett Jr WH, "Role of the p16 tumor suppressor gene in cancer" 16 : 1197-1206, 1998
10 Copper MP, "Role of genetic factors in the etiology of squamous cell carcinoma of the head and neck" 121 : 157-160, 1995
1 Shin DM, "p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma" 88 : 519-529, 1996
2 Chang X, "dentification of hypermethylated genes associated with cisplatin resistance in human cancers" 1 (1): 2870-2879, 2010
3 Rosin MP, "Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia" 6 : 357-, 2000
4 Folkman J, "Tumor angiogenesis: therapeutic implications" 18 (18): 1182-1186, 1971
5 Field JK, "The role of the p53 tumor suppressor gene in squamous cell carcinoma of the head and neck" 119 : 1118-1122, 1993
6 Xie X, "The prognostic value of spontaneous apoptosis. Bax, Bcl- 2, and p53 in oral squamous cell carcinoma of the tongue" 86 : 913-920, 1999
7 Partridge M, "The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer" 79 : 1821-1827, 1999
8 Strome SE, "Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations" 8 : 1093-1100, 2002
9 Liggett Jr WH, "Role of the p16 tumor suppressor gene in cancer" 16 : 1197-1206, 1998
10 Copper MP, "Role of genetic factors in the etiology of squamous cell carcinoma of the head and neck" 121 : 157-160, 1995
11 Bonner JA, "Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck" 354 : 567-578, 2006
12 Esteller M, "Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors" 5 (5): 564-569, 2000
13 Bettendorf O, "Prognostic and predictive factors in oral squamous cell cancer: important tools for planning individual therapy?" 40 : 110-119, 2004
14 Callender T, "PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma" 74 : 152-158, 1994
15 Mehanna H, "Oropharyngeal carcinoma related to human papillomavirus" 25 (25): 1439-, 2010
16 Nagpal JK, "Oral cancer: reviewing the present understanding of its molecular mechanism and exploring the future directions for its effective management" 39 : 213-221, 2003
17 Patel V, "New approaches to the understanding of the molecular basis of oral cancer" 12 : 55-63, 2001
18 "National Cancer Institute, Study Estimates Overall HPV Prevalence in U.S. Women"
19 Nigro JM, "Mutations in the p53 gene occur in diverse human tumour types" 342 : 705-708, 1989
20 Le Tourneau C, "Molecular targeted therapy of head and neck cancer: review and clinical development challenges" 43 : 2457-2466, 2007
21 Pai SI, "Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment" 4 : 49-70, 2009
22 Williams HK, "Molecular pathogenesis of oral squamous carcinoma" 53 : 165-172, 2000
23 Figueiredo ML, "Molecular mechanisms of head and neck cancer" 1 : 273-281, 2004
24 Gleich LL, "Molecular genetics of head and neck cancer" 9 : 369-378, 2002
25 Brennan JA, "Molecular assessment of histopathological staging in squamouscell carcinoma of the head and neck" 332 : 429-435, 1995
26 Rubin Grandis J, "Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival" 90 : 824-832, 1998
27 Bockmuhl U, "Improved prognostic assessment of head-neck carcinomas by new genetic markers" 48 : 451-456, 2000
28 McDonald JS, "Immunhistochemical detection of the Hras, K-ras, and N-ras oncogenes in squamous cell carcinoma of the head and neck" 23 : 342-346, 1994
29 Mellin H, "Humanpapillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival" 89 : 300-304, 2000
30 Sisk EA, "Human papillomavirus and p53 mutational status as prognostic factors in head and neck carcinoma" 24 : 841-849, 2002
31 Bockmuhl U, "Genomic alterations associated with malignancy in head and neck cancer" 20 : 145-151, 1998
32 Scully C, "Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations" 36 : 311-327, 2000
33 Califano J, "Genetic Progression Model for Head and Neck Cancer: Implications for Field Cancerization" 56 : 2488-2492, 1996
34 Herman JG, "Gene silencing in cancer in association with promoter hypermethylation" 349 : 2042-2054, 2003
35 Sanchez-Cespedes M, "Gene promoter hypermethylation in tumors and serum of head and neck cancer patients" 15 : 892-895, 2000
36 Ishitoya J, "Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck" 59 : 559-562, 1989
37 Slaughter DP, "Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin" 6 : 963-968, 1953
38 Foulkes WD, "Familial risks of squamous cell carcinoma of thehead and neck: a retrospective case-control study" 313 : 716-720, 1996
39 Parkin DM, "Estimates of the worldwide frequency of sixteen major cancers in 1980" 41 : 184-189, 1988
40 Cripps C, "Epidermal growth factor receptor targeted therapy in stages III and IV head and neck cancer" 17 : 37-48, 2010
41 Bentzen SM, "Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial" 23 : 5560-5567, 2005
42 Dobosy JR, "Emerging connections between DNA methylation and histone acetylation" 58 : 721-727, 2001
43 Nobori T, "Deletions of the cyclin-dependent kinase- 4 inhibitor gene in multiple human cancers" 368 : 753-756, 1994
44 Kyomoto R, "Cyclin D1 gene amplification is a more potent prognostic factor than its protein overexpression in human head and neck squamous cell carcinoma" 74 : 576-581, 1997
45 Gillespie MB, "Curr Treat Options Oncol" 10 : 296-307, 2009
46 Williams ME, "Chromosome 11Q13 amplification in head and neck squamous cell carcinoma" 119 : 1238-1243, 1993
47 D’Souza G, "Casecontrol study of human papillomavirus and oropharyngeal cancer" 356 : 1944-1956, 2007
48 Werness BA, "Association of human papillomavirus types 16 and 18 E6 proteins with p53" 248 : 76-79, 1990
49 Glazer CA, "Applying the molecular biology and epigenetics of head and neck cancer in everyday clinical practice" 45 : 440-446, 2009
50 Xu J, "Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use" 83 : 204-212, 1998
51 Cruz IB, "Age-dependence of human papillomavirus DNA presence in oral squamous cell carcinomas" 32 : 55-62, 1996
52 Serrano M, "A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4" 366 : 704-707, 1993
53 Khuri FR, "A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer" 6 : 879-885, 2000
54 Bockmuhl U, "8. Bockmuhl U, Schwendel A, Dietel M, Petersen I. Distinct patterns of chromosomal alterations in highand low-grade head and neck squamous cell carcinomas" 56 : 5325-5329, 1996