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    Effect of Combined Extract of Hansogdan (Phlomis umbrosa) and Dalgaebi (Commelina communis) as a Milk Additive for Enhancing the Growth of Physical Height in vivo

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    https://www.riss.kr/link?id=A104492765

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    Three different dosage groups for the mixed plant extract of hansogdan (Phlomis umbrosa) and dalgaebi (Commelina communis) (5, 25, and 100 mg/kg/day respectively) were evaluated in rats for the investigation of the enhancement of growth of physical height as a milk additive. Comparing to control group, the nose-to-tail (NT)length was significantly increased in all treatment groups with a dose dependent manner, nose-to-anus (N-A)length was increased significantly in 25 and 100 mg/kg groups, the increase in both N-T and N-A lengths in 100mg/kg group was almost same to that of positive group,and the femoral bone length in 25 mg/kg group was significantly increased. In result, the consumption of the mixed extract with milk could stimulate the longitudinal growth and that the addition of the mixed herbal extract into the milk could be more effective than milk itself in terms of the growth of physical height in rats.
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    Three different dosage groups for the mixed plant extract of hansogdan (Phlomis umbrosa) and dalgaebi (Commelina communis) (5, 25, and 100 mg/kg/day respectively) were evaluated in rats for the investigation of the enhancement of growth of physical he...

    Three different dosage groups for the mixed plant extract of hansogdan (Phlomis umbrosa) and dalgaebi (Commelina communis) (5, 25, and 100 mg/kg/day respectively) were evaluated in rats for the investigation of the enhancement of growth of physical height as a milk additive. Comparing to control group, the nose-to-tail (NT)length was significantly increased in all treatment groups with a dose dependent manner, nose-to-anus (N-A)length was increased significantly in 25 and 100 mg/kg groups, the increase in both N-T and N-A lengths in 100mg/kg group was almost same to that of positive group,and the femoral bone length in 25 mg/kg group was significantly increased. In result, the consumption of the mixed extract with milk could stimulate the longitudinal growth and that the addition of the mixed herbal extract into the milk could be more effective than milk itself in terms of the growth of physical height in rats.

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    참고문헌 (Reference)

    1 최철석, "식물추출물(YGF)의 IGF-1 분비촉진에 미치는 영향" 한국생물공학회 17 (17): 203-206, 2002

    2 Mi-Yeon Kim, "The Herbal Formula HT042 Induces Longitudinal Bone Growth in Adolescent Female Rats" 한국식품영양과학회 13 (13): 1376-1384, 2010

    3 Shiotani A, "Skeletal muscle regeneration after insulin-like growth factor I gene transfer by recombinant Sendai virus vector" 8 : 1043-1050, 2001

    4 Blum WF, "Serum levels of insulin-like growth factor I (IGF-I) and IGF binding protein 3 reflect spontaneous growth hormone secretion" 76 : 1610-1616, 1993

    5 Matkovic V, "Nutrition influences skeletal development from childhood to adulthood: A study of hip, spine, and forearm in adolescent females" 134 : 701S-705S, 2004

    6 Woods KA, "Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene" 335 : 1363-1367, 1996

    7 Arsenijevic Y, "Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2" 21 : 7194-7202, 2001

    8 Ranke MB, "Insulin-like growth factor I improves height in growth hormone insensitivity: Two years' results" 44 : 253-264, 1995

    9 Jeong YC, "Growth effects of recombinant human growth hormone" 3 : 233-237, 1995

    10 Woods KA, "Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion" 85 : 1407-1411, 2000

    1 최철석, "식물추출물(YGF)의 IGF-1 분비촉진에 미치는 영향" 한국생물공학회 17 (17): 203-206, 2002

    2 Mi-Yeon Kim, "The Herbal Formula HT042 Induces Longitudinal Bone Growth in Adolescent Female Rats" 한국식품영양과학회 13 (13): 1376-1384, 2010

    3 Shiotani A, "Skeletal muscle regeneration after insulin-like growth factor I gene transfer by recombinant Sendai virus vector" 8 : 1043-1050, 2001

    4 Blum WF, "Serum levels of insulin-like growth factor I (IGF-I) and IGF binding protein 3 reflect spontaneous growth hormone secretion" 76 : 1610-1616, 1993

    5 Matkovic V, "Nutrition influences skeletal development from childhood to adulthood: A study of hip, spine, and forearm in adolescent females" 134 : 701S-705S, 2004

    6 Woods KA, "Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene" 335 : 1363-1367, 1996

    7 Arsenijevic Y, "Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2" 21 : 7194-7202, 2001

    8 Ranke MB, "Insulin-like growth factor I improves height in growth hormone insensitivity: Two years' results" 44 : 253-264, 1995

    9 Jeong YC, "Growth effects of recombinant human growth hormone" 3 : 233-237, 1995

    10 Woods KA, "Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion" 85 : 1407-1411, 2000

    11 Ballard TNP, "Effect of protein supplementation during a 6-month strength and conditioning program on insulin-like growth factor I and markers of bone turnover in young adults" 81 : 1442-1448, 2005

    12 Jansson JO, "Effect of frequency of growth hormone administration on longitudinal bone growth and body weight in hypophysectomized rats" 114 : 261-265, 1982

    13 Kim OK, "Effect of Commelina communis extract on blood glucose level and changes in alloxan-diabetic rats" 22 : 225-232, 1991

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    연월일 이력구분 이력상세 등재구분
    2023 평가 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
    2020-01-01 등재 등재학술지 유지 (해외등재 학술지 평가) KCI등재
    2010-11-23 학회명변경 영문명 : Korean Society Of Food Science And Biotechnology -> Korean Society of Food Science and Technology KCI등재
    2010-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2008-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2006-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2004-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2001-07-01 등재 등재학술지 선정 (등재후보2차) KCI등재
    1999-01-01 등재 등재후보학술지 선정 (신규평가) KCI등재후보
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    기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
    2016 0.75 0.17 0.56
    KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
    0.49 0.43 0.364 0.06
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