위전절제술후 알칼리성 역류성 식도염에서의 식도운동성 검사에 관한 연구 = Correlation between Esophageal Motility Disturbance and Inflammation in Patients of Alkaline Reflux Esophagitis Following Total Gastrectomy

다국어 초록 (Multilingual Abstract)

We performed esophageal manometry and endoscopy with biopsy of ten patients who had undergone total gastrectomy due to advanced stomach cancer in the high body (not involving GE junction or cardia) between 3 weeks and 2 year 3 months after surgery. The study was undertaken to evaluate the esophageal motility distrurbance and compare with the pathologic severity of esophagitis. In nine cases, the primary peristalsis failed at the frequency of over 60%, and in 4 cases of which the failure rate was 100%. In these 4 cases severe submucosal inflammatory cell iinfiltration was observed, exhibiting positive correlation between motility disturbance and histologic damage. The types of failed primary peristalsis included no generation of peristalsis, simultaneous contractions and retrograde peristalsis. The retrograde peristalsis was observed in 4 cases, 3 cases of which exhibited severe histological inflammation as well as total failure in primary peristaltic sequence. The exam results did not change during the period of 2 to 5 moths of follwing check-up in 5 cases.