위 조직편 접촉세포검사의 진단적 의의 = The Diagnostic Significance of the Specimen Touch Cytology in Gastric Lesions위 조직편 접촉세포검사의 진단적 의의

다국어 초록 (Multilingual Abstract)

Background/Aims: Currently, the endoscopic biopsy technique is the most accurate diagnostic modality detecting the ga'tric carcinoma. But, it is thought importantly to evaluate the significance of touch cytology in diagnosing the gastric lesion because the representative area of gastric lesion is possible to be removed during the process making the specimen. Methods. After l,333 cytologic specimens from 1,235 patients were made by touch of the biopsied tissue on the slide glass and were stained by Papanecolaous method, the tissue specimens were obtained by the usual specimen making technique. The results of the cytologic diagnosis were compared to the biopsy results. Results: The accuracy of the cytologic diagnosis was 99.0%(1,108/1,119 cases) in the gastritis or benign ulcer, 20.4%(11/54 cases) in the atypical epithelial lesions, and 75.0%(120/160 cases) in the malignancy. The overall accuracy of the cytologic diagnosis was 92.9%(1,239/1,333 cases). False positivity of the cytologic diagnosis was 0.4%(5/1,177 cases) and false negativity was 16.9%(27/ 160 cases). All of the 4 cases, which were diagnosed class IV or V in the cytologic diagnosis and gastritis or benign ulcer in the biopsy diagnosis in the first study, were found to be benign lesions in the follow up cytologic and biopsy studies. Conclusion: This study indicates that touch cytologic examinations supplementary to biopsies are not so significant enough to performed spending many efforts since biopsied specimen represent the majority of gastric lesion, if they were sampled at correct site of lesion at all. (Korean J Gastroenterol 1995;27: 517 - 513)