하악골절 환자에서 악관절강내 활액의 PGE₂농도분석 = Analysis of PGE2 Concentration in Synovial Fluid Aspirates from TMJs of Patients with Mandibular Fracture

다국어 초록 (Multilingual Abstract)

The purpose of this study is to examine the change of enzymeimmuno-assay for prostaglandinE_2 in the synovial fluid lavage specimen of patients with mandibular fracture patients without condylar fracture.
For this study, fourteen patients (eight males, six females) with mandibular fractures without condylar fracture was investigated to analyse the synovial fluid form upper temporomandibular joint cavities. Synovial fluid was collected from TMJ cavities of mandibular fracture patients before open reduction and after one week of open reduction, and then stored in liquid nitrogen tank after centrifuge. 2 synovial fluid lavage samples of TMJs of 2 asymptomatic served as normal controls referred from other data.
The concentrations of PGE_2 were measured by use of PGE_2 EIA system (Amersham＾(R)).
The following results were obtained:
1. In nine patients, the concentrations of PGE_2 are lower after open reduction than before.
2. In three patients, the concentrations of PGE_2 are higher after open reduction than before.
3. There was no statistical significant between the preoperative group and postoperative 7 days (p>0.05), but there was some difference between the two groups.
In conclusion, the results suggest that PGE_2 probably does no play as important role in the harm of TMJ.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅱ. 연구대상 및 방법
• Ⅲ. 연구결과
• Ⅳ. 총괄 및 고찰
• Ⅴ. 결론
• 참고문헌