Phenolic amides from Tribulus terrestris and their inhibitory effects on nitric oxide production in RAW 264.7 cells

다국어 초록 (Multilingual Abstract)

A new phenolic amide, named cis-terrestriamide(7), together with ten known compounds (1–6, 8–11), wereisolated from the methanolic extract of the fruits ofTribulus terrestris. The structure of 7 was elucidated on thebasis of extensive analyses of 1D and 2D nuclear magneticresonance spectroscopic and high resolution mass spectrometrydata. Compounds 1, 2, 5, 6, 8, 9, and 11 exhibitedinhibitory effects on the lipopolysaccharide-stimulatednitric oxide production in RAW 264.7 cells, with IC50values of 18.7–49.4 lM.

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