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      전정자율신경반사의 해부생리적 특징과 임상 발현 = Anatomic and Physiologic Properties and Clinical Manifestations of Vestibulo-Autonomic Reflexes

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      https://www.riss.kr/link?id=A108326732

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      다국어 초록 (Multilingual Abstract)

      The vestibular nervous system senses linear and angular acceleration upon the head during postural change and generates vestibular nerve activity changes. The autonomic nervous system regulates involuntary physiologic processes throughout the peripheral and central nervous systems. The vestibular and autonomic systems interplay throughout several brain regions to maintain homeostasis during the postural changes, called vestibuloautonomic reflex. In this review, we first contemplated the anatomic and physiologic properties of vestibuloautonomic reflex, focusing on the relationship between vestibular and cardiovascular systems and between the vestibular and respiratory systems and the role of the brainstem and cerebellum on the vestibuloautonomic reflex. Then, we summarized the autonomic dysfunction reported in patients with various vestibular disorders, such as acute unilateral vestibulopathy, benign paroxysmal positional vertigo, Meniere’s disease, and persistent perceptual postural dizziness. Finally, we described the mechanism of autonomic manifestation in vestibular disorders in detail using the recently proposed mechanism of vestibular syncope integrating the vestibular system, brainstem and cerebellum, and autonomic system functions
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      The vestibular nervous system senses linear and angular acceleration upon the head during postural change and generates vestibular nerve activity changes. The autonomic nervous system regulates involuntary physiologic processes throughout the peripher...

      The vestibular nervous system senses linear and angular acceleration upon the head during postural change and generates vestibular nerve activity changes. The autonomic nervous system regulates involuntary physiologic processes throughout the peripheral and central nervous systems. The vestibular and autonomic systems interplay throughout several brain regions to maintain homeostasis during the postural changes, called vestibuloautonomic reflex. In this review, we first contemplated the anatomic and physiologic properties of vestibuloautonomic reflex, focusing on the relationship between vestibular and cardiovascular systems and between the vestibular and respiratory systems and the role of the brainstem and cerebellum on the vestibuloautonomic reflex. Then, we summarized the autonomic dysfunction reported in patients with various vestibular disorders, such as acute unilateral vestibulopathy, benign paroxysmal positional vertigo, Meniere’s disease, and persistent perceptual postural dizziness. Finally, we described the mechanism of autonomic manifestation in vestibular disorders in detail using the recently proposed mechanism of vestibular syncope integrating the vestibular system, brainstem and cerebellum, and autonomic system functions

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      참고문헌 (Reference)

      1 김현아 ; 이형, "현훈 진단에 있어 함정" 대한신경과학회 36 (36): 280-288, 2018

      2 Yates BJ, "Vestibulo"sympathetic responses" 4 : 851-, 2014

      3 Bogle JM, "Vestibular"autonomic inter"actions : beyond orthostatic dizziness" 35 : 126-, 2022

      4 Kwon H, "Vestibular syncope : clinical characteristics and mechanism" 9 : 1616-, 2022

      5 Pyykkö I, "Vestibular syncope : a disorder associated with drop attack in ménière's disease" 45 : 234-, 2018

      6 Kerman IA, "Vestibular stimulation leads to dis"tinct hemodynamic patterning" 279 : R118-R125, 2000

      7 Yates BJ, "Vestibular influences on the sympathetic nervous system" 17 : 51-, 1992

      8 Rossiter CD, "Vestibular influences on hypoglossal nerve ac"tivity in the cat" 211 : 25-, 1996

      9 Jáuregui"Renaud K, "Vestibular function interferes in cardiovascular re"flexes [corrected]" 34 : 200-, 2003

      10 Siniaia MS, "Vestibular effects on upper airway musculature" 736 : 160-, 1996

      1 김현아 ; 이형, "현훈 진단에 있어 함정" 대한신경과학회 36 (36): 280-288, 2018

      2 Yates BJ, "Vestibulo"sympathetic responses" 4 : 851-, 2014

      3 Bogle JM, "Vestibular"autonomic inter"actions : beyond orthostatic dizziness" 35 : 126-, 2022

      4 Kwon H, "Vestibular syncope : clinical characteristics and mechanism" 9 : 1616-, 2022

      5 Pyykkö I, "Vestibular syncope : a disorder associated with drop attack in ménière's disease" 45 : 234-, 2018

      6 Kerman IA, "Vestibular stimulation leads to dis"tinct hemodynamic patterning" 279 : R118-R125, 2000

      7 Yates BJ, "Vestibular influences on the sympathetic nervous system" 17 : 51-, 1992

      8 Rossiter CD, "Vestibular influences on hypoglossal nerve ac"tivity in the cat" 211 : 25-, 1996

      9 Jáuregui"Renaud K, "Vestibular function interferes in cardiovascular re"flexes [corrected]" 34 : 200-, 2003

      10 Siniaia MS, "Vestibular effects on upper airway musculature" 736 : 160-, 1996

      11 Yates BJ, "Vestibular effects on respiratory outflow in the decerebrate cat" 629 : 209-, 1993

      12 James C, "Vestibular and pulse"related modu"lation of skin sympathetic nerve activity during sinusoidal galvanic vestibular stimulation in human subjects" 202 : 291-, 2010

      13 Groves DA, "Vagal nerve stimulation : a review of its applica"tions and potential mechanisms that mediate its clinical effects" 29 : 493-, 2005

      14 Morita H, "Understanding vestibular"related physiological functions could provide clues on adapting to a new grav"itational environment" 70 : 17-, 2020

      15 Day BL, "The vestibular system" 15 : R583-R586, 2005

      16 Brandt T, "The vestibular cortex. Its locations, functions, and disorders" 871 : 293-, 1999

      17 Cohen B, "The neural basis of motion sickness" 121 : 973-, 2019

      18 Nagai M, "The insular cortex as a ves"tibular area in relation to autonomic function" 31 : 179-, 2021

      19 Fulwiler CE, "Subnuclear organization of the efferent con"nections of the parabrachial nucleus in the rat" 319 : 229-, 1984

      20 Rabbitt RD, "Semicircular canal biomechanics in health and disease" 121 : 732-, 2019

      21 Yates BJ, "Role of the vestibular system in regulating respiratory muscle activity during movement" 29 : 112-, 2002

      22 Mori RL, "Role of the medial me"dullary reticular formation in relaying vestibular signals to the dia"phragm and abdominal muscles" 902 : 82-, 2001

      23 Kim JB, "Right insular atrophy in neurocardiogenic syncope : a volumetric MRI study" 35 : 113-, 2014

      24 Bielanin JP, "Responses of neurons in the medullary lateral tegmental field and nucleus tractus solitarius to vestibular stimuli in conscious felines" 11 : 620817-, 2020

      25 Ishii M, "Relationship between the onset of ménière's disease and sympathetic hyperactivity" 13 : 804777-, 2022

      26 Guz A, "Regulation of respiration in man" 37 : 303-, 1975

      27 Reschke MF, "Posture, locomotion, spatial orientation, and motion sickness as a function of space flight" 28 : 102-, 1998

      28 Whitman GT, "Orthostatic intolerance in acute vestibular neuritis" 90 : 308-, 2015

      29 Kim HA, "Orthostatic hypotension in acute vestibular neuritis" 358 : 479-, 2015

      30 Yates BJ, "Organization of vestibular inputs to nucleus tractus solitarius and ad"jacent structures in cat brain stem" 267 : R974-R983, 1994

      31 Eren OE, "Non"invasive vagus nerve stimulation significantly improves quality of life in patients with persistent postural"perceptual dizziness" 265 : 63-, 2018

      32 Bent LR, "Modulation of muscle sympathetic bursts by sinusoidal galvanic vestibular stimulation in human subjects" 174 : 701-, 2006

      33 Fujita H, "Modular output circuits of the fastigial nucleus for diverse motor and nonmotor functions of the cerebellar vermis" 9 : e58613-, 2020

      34 Morita H, "Long"term exposure to microgravity im"pairs vestibulo"cardiovascular reflex" 6 : 33405-, 2016

      35 Furman JM, "Interface between vestibular dys"function and anxiety : more than just psychogenicity" 22 : 426-, 2001

      36 Cotter LA, "Effects of postural changes and vestibular lesions on diaphragm and rectus abdominis activity in awake cats" 91 : 137-, 2001

      37 Park BR, "Effects of acute hypotension on neuronal activity in the medial vestibular nuclei of rats" 12 : 3821-, 2001

      38 Baloh RW, "Drop attacks with menière's syndrome" 28 : 384-, 1990

      39 Yang AHX, "Directional effects of whole"body spinning and visual flow in virtual reality on vagal neuromodulation" 31 : 479-, 2021

      40 Staab JP, "Diagnostic criteria for persistent postural"perceptual dizziness(PPPD) : consensus document of the committee for the classification of ves"tibular disorders of the bárány society" 27 : 191-, 2017

      41 McCall AA, "Descending influences on vestibulo"spinal and vestibulosympathetic reflexes" 8 : 112-, 2017

      42 Billig I, "Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneur"ons in the ferret using recombinant strains of pseudorabies virus" 20 : 7446-, 2000

      43 Hallgren E, "Decreased otolith"mediated vestibular response in 25 as"tronauts induced by long"duration spaceflight" 115 : 3045-, 2016

      44 Cechetto DF, "Cortical control of the autonomic nervous system" 99 : 326-, 2014

      45 Furman JM, "Clinical evidence that the ves"tibular system participates in autonomic control" 8 : 27-, 1998

      46 Dampney RA, "Central neural control of the cardiovascular system : current perspectives" 40 : 283-, 2016

      47 Kwon E, "Can dyssynergia of vestibu losympathetic and baroreflexes cause vestibular syncope? The hypoth esis based on the velocity storage function" 21 : 244-, 2022

      48 Pakdaman MN, "Blood"labyrinth barrier permeability in menière disease and idi"opathic sudden sensorineural hearing loss : findings on delayed post"contrast 3D"FLAIR MRI" 37 : 1903-, 2016

      49 Yamada M, "Autonomic nervous function in patients with Meniere's disease evaluated by pow"er spectral analysis of heart rate variability" 26 : 419-, 1999

      50 Kim HA, "Autonomic dysfunction as a possible cause of residual dizziness after successful treatment in benign paroxysmal positional vertigo" 125 : 608614-, 2014

      51 Waxenbaum JA, "Anatomy, autonomic nervous system"

      52 Riccelli R, "Altered insular and occipital responses to simulated vertical self"mo"tion in patients with persistent postural"perceptual dizziness" 8 : 529-, 2017

      53 Toschi N, "Altered autonomic response in patients with persistent postur al perceptual dizziness during simulated vertical self motion" IEEE 1-2, 2011

      54 Bolton PS, "Absence of short"term ves"tibular modulation of muscle sympathetic outflow, assessed by brief galvanic vestibular stimulation in awake human subjects" 154 : 39-, 2004

      55 Brignole M, "2018 ESC guidelines for the diagnosis and management of syncope" 39 : 1883-, 2018

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