돼지 대동맥판막을 이용한 이첨판 대동맥판막 후류 유동 분석

다국어 초록 (Multilingual Abstract)

Aortic valvular stenosis where calcium accumulates in the valve and the valve hardens is the most common heart valve disease in developed countries. The type of aortic valves is generally divided into tricuspid aortic valve (TAV) and congenital malformation bicuspid aortic valve (BAV) stenosis. Although flow characteristics of TAV have been well established, that of BAV is still not fully unelucidated. In this study, we proposed an ex vivo flow visualization platform by using a pig heart. Normal TAV and BAV models were prepared by aortic valve plastic surgery. Valve wake flow characteristics of normal TAV and BAV were compared by using 4D flow magnetic resonance imaging. Normal TAV exhibited that the valve was fully opened during systole, while the valve of BAV was partially opened. The Stroke volume of the normal TAV and BAV were similar. However, the peak velocity of BAV was higher than that of the TAV. The effect of malfunction of BAV on hemodynamics was systematically analyzed. This study would be helpful for diagnosing aortic stenosis and understanding prognosis prediction especially for aortic stenosis patients with BAV.

목차 (Table of Contents)

• Abstract
• 1. 서론
• 2. 이론 및 실험
• 3. 결론
• 참고문헌