개 혈청화학검사항목의 장기간의 개체 내 변이와 critical difference = Long-term intra-individual variations and critical differences of clinical chemical parameters in dogs

다국어 초록 (Multilingual Abstract)

The purpose of this study was to assess intra-individual variations of clinicochemical parameters and calculate critical differences in healthy dogs during long-term periods. To calculate the critical difference of clinicochemical parameters, blood samples from 20 apparently clinically healthy dogs were collected once weekly for eight consecutive weeks. The critical difference was calculated as 9.01mg/dl for urea, 0.52mg/dl for creatinine, 0.99g/dl for total protein, 0.39g/dl for albumin, and 20.64mg/dl for glucose. If two consecutive results differ by less than the critical difference value, it can be concluded that the difference is probably due to physiological variation. However, when the difference is greater than the critical value, other factors, either related to progression of the disease or the presence of concurrent disease, are more likely to be involved.

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