Evaluation of Cadmium-Zinc-Telluride Detector-based Single-Photon Emission Computed Tomography for Nuclear Cardiology: a Comparison with Conventional Anger Single-Photon Emission Computed Tomography

다국어 초록 (Multilingual Abstract)

Purpose The differences in performance between the cadmium-zinc-telluride (CZT) camera or collimation systems and conventional Anger single-photon emission computed tomography (A-SPECT) remain insufficient from the viewpoint of the user. We evaluated the performance of the D-SPECT (Spectrum Dynamics, Israel) system to provide more information to the cardiologist or radiological technologist about its use in the clinical field.
Materials and Methods This study evaluated the performance of the D-SPECTsystem in terms of energy resolution, detector sensitivity, spatial resolution, modulation transfer function (MTF), and collimator resolution in comparison with that of A-SPECT (Bright-View, Philips, Japan). Energy resolution and detector sensitivity were measured for Tc-99m, I-123, and Tl-201. The SPECT images produced by both systems were evaluated visually using the anthropomorphic torso phantom.
Results The energy resolution of D-SPECT with Tc-99m and I-123 was approximately two times higher than that of ASPECT.
The detector sensitivity of D-SPECTwas higher than that of A-SPECT (Tc-99m: 4.2 times, I-123: 2.2 times, and Tl- 201: 5.9 times). The mean spatial resolution of D-SPECTwas two times higher than that of A-SPECT. The MTF of DSPECT was superior to that of the A-SPECT system for all frequencies. The collimator resolution of D-SPECTwas lower than that of A-SPECT; however, the D-SPECT images clearly indicated better spatial resolution than the A-SPECT images.
Conclusion The energy resolution, detector sensitivity, spatial resolution, and MTF of D-SPECTwere superior to those of ASPECT.
Although the collimator resolution was lower than that of A-SPECT, the D-SPECT images were clearly of better quality.

참고문헌 (Reference)

1 Anger HO, "Scintillation camera with multichannel collimators" 5 : 515-531, 1964

2 Zaman MU, "Recent developments and future prospects of SPECTmyocardial perfusion imaging" 24 : 565-569, 2010

3 Nakazato R, "Quantitative upright-supine high-speed SPECT myocardial perfusion imaging for detection of coronary artery disease : correlation with invasive coronary angiography" 51 : 1724-1731, 2010

4 Park MA, "Performance of a high-sensitivity dedicated cardiac SPECTscanner for striatal uptake quantification in the brain based on analysis of projection data" 40 : 042504-, 2013

5 NEMA Standards Publication, "Performance measurements of gamma cameras. NU 1-2012"

6 Erlandsson K, "Performance evaluation of D-SPECT : a novel SPECT system for nuclear cardiology" 54 : 2635-2649, 2009

7 Cutler SJ, "Observer detection limits for a dedicated SPECT breast imaging system" 55 : 1903-1916, 2010

8 Nakazato R, "Myocardial perfusion imaging with a solid-state camera : simulation of a very low dose imaging protocol" 54 : 373-379, 2013

9 Neill J, "Initial multicenter experience of high-speed myocardial perfusion imaging : comparison between high-speed and conventional single-photon emission computed tomography with angiographic validation" 40 : 1084-1094, 2013

10 Berman DS, "Improvement in PET myocardial perfusion image quality and quantification with flurpiridaz F 18" 19 (19): S38-S45, 2012

11 Hara T, "Image quality dependence on in-plane positions and directions for MDCT images" 75 : 114-121, 2010

12 Duvall WL, "High-efficiency SPECT MPI : comparison of automated quantification, visual interpretation, and coronary angiography" 20 : 763-773, 2013

13 Verger A, "Factors affecting the myocardial activity acquired during exercise SPECT with a high-sensitivity cardiac CZT camera as compared with conventional Anger camera" 41 : 522-528, 2014

14 Claudin M, "Evaluation of left ventricular function using a semiconductor gamma camera and a fast low-dose protocol" 39 : 401-408, 2015

15 Ogawa K, "Development of an ultra-high resolution SPECT system with a CdTe semiconductor detector" 23 : 763-770, 2009

16 Ben-Haim S, "Clinical value of supine and upright myocardial perfusion imaging in obese patients using the D-SPECT camera" 21 : 478-485, 2014

17 Garcia EV, "Cardiac dedicated ultrafast SPECT cameras : new designs and clinical implications" 52 : 210-217, 2011

18 Hain SF, "Can upright myocardial perfusion imaging be used alone with a solid-state dedicated cardiac camera?" 57 : 383-390, 2013

19 Germano G, "Automatic quantification of ejection fraction from gated myocardial perfusion SPECT" 36 : 2138-2147, 1995

20 Lee CJ, "Assessment of cardiac singlephoton emission computed tomography performance using a scanning linear observer" 40 : 011906-, 2013

21 Samartzis AP, "A robust method, based on a novel source, for performance and diagnostic capabilities assessment of the positron emission tomography system" 17 : 97-105, 2014

22 Gambhir SS, "A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera" 50 : 635-643, 2009