Phenolic Compounds with Antioxidant Activity on DPPH Free Radical Scavenging and Inhibition of Xanthine/Xanthine Oxidase from the Flowers of Chrysanthemum morifolium

다국어 초록 (Multilingual Abstract)

The flowers of Chrysanthemum morifolium (Compositae) were investigated for their biofunctional components. Antioxidant compounds were identified from the flower of Chrysanthemum morifolium, through activity-guided fractionation and repeated column chromatographic separations. The structures of the isolated compounds were characterized as chlorogenic acid (1), luteolin (2) and quercitrin (3) by the analysis of physico-chemical and spectral data. Their antioxidant effects were evaluated by assaying for 1,1-diphenyl-2-picrylhydrazyl free radical scavenging activity and inhibition of xanthine/xanthine oxidase activity.

목차 (Table of Contents)

• Abstract
• INTRODUCTION
• MATERIALS AND METHODS
• RESULTS AND DISCUSSION
• ACKNOWLEDGEMENT
• REFERENCES

참고문헌 (Reference)

1 "Two acidic polysaccharides from the flowers of Chrysanthemum morifolium" 8 : 217-222, 2006

2 "The Systematic Identification of Flavonoids" 1970

3 "Studies on the mechanism of action of antitumor promoting agents Suggestive evidence for the involvement of free radicals in promotion" Academic Press -485, 1983

4 "Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA" 426 : 591-593, 1998

5 "Medicinal plants with cytotoxic and antioxidative activity In Recent progress in medicinal plants" 12 : 193-202, 2006

6 "Inhibitory effects of phenolics on xanthine oxidase" 14 : 501-506, 1994

7 "Inhibitory effects of curcumin and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol 13-acetate" 48 : 5941-5946, 1988

8 "Inflammation and oxidative stress in carcinogenesis" 3 : 1-7, 1991

9 "Handbook of Biologically Active Phytochemicals and Their Activities" CRC Press 1992

10 "GC-MS analysis of essential oil of the flower of the Chrysanthemum morifolium by the different processing methods" 31 : 456-459, 2006

11 "Foods from Herb" Seoul National University press -22, 1999

12 "Flavonoids are scavengers of superoxide anion" 37 : 837-841, 1988

13 "Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers." 177 : 7-12, 2002

14 "Comparison on antioxidant activity of Korean teas" -520, 2004

15 "Carbon-13 nuclear magnetic resonance spectroscopy of flavonoid and isoflavonoid compounds" 16 : 1811-1816, 1977

16 "Carbon-13 NMR studies of flavonoid glycosides and their acylated derivatives" 34 : 1389-1397, 1978

17 "Antioxidant properties of hydroxy- flavones" 20 : 35-43, 1996

18 "Antioxidant flavonoids and chlorogenic acid from Eriobotrya japonica" 22 : 213-218, 1999

19 "A quinolone alkaloid with antioxidant activity from the aleurone layer of anthocyanin-pigmented rice" 64 : 1579-1580, 2001

20 "A new anti-HIV flavonoid glucuronide from Chrysanthemum morifolium" 69 : 859-861, 2003