히알루론 산을 이용한 비수술적 눈꺼풀 위치 이상의 치료효과 = Nonsurgical Treatment of Abnormal Eyelid Position Using Hyaluronic Acid Gel

다국어 초록 (Multilingual Abstract)

Purpose: The present study investigated the outcomes of nonsurgical treatment of abnormal eyelid position using hyaluronic acid gel. Methods: Abnormal eyelid position including 18 eyes with lid retraction, 10 eyes with lagophthalmos, and 18 eyes with ectropion were treated with hyaluronic acid gel. The mean age was 50 ± 17.8 years and the mean observation period was 11 ± 2.4 months. The photographs of patients were taken before injection, 1 month, 4 months, and at the last follow-up after injection. The marginal reflex distance 1 (MRD1) and marginal reflex distance 2 (MRD2) of patients were measured and analyzed by the Image J Program. The severity of ectropion was graded by a scoring system. Results: Ten eyes with lagopthalmos improved 1.9 ± 1.2 mm after injection. The 16 eyes with lid retraction improved 1.3 ± 0.9 mm. Twenty-three eyes with ectropion improved and 17 eyes (81%) were completely corrected. The average frequency of injection was 1.1 and the average dose of injection was 0.4 ± 0.12 cc. No significant complications were observed in any patient. Conclusions: Hyaluronic acid gel injections can be used safely and effectively as a nonsurgical treatment for patients with abnormal eyelid position without any significant complications. J Korean Ophthalmol Soc 2012;53(3):357-364

참고문헌 (Reference)

1 Lambros V, "Volumizing the brow with hyaluronic acid fillers" 29 : 174-179, 2009

2 Donath AS, "Volme loss versus gravity: new concepts in facial aging" 15 : 238-243, 2007

3 Morley AM, "Use of hyaluronic acid gel for upper eyelid filling and contouring" 25 : 440-444, 2009

4 Gold MH, "Use of hyaluronic acid fillers for the treatment of the aging face" 2 : 369-376, 2007

5 Kane MA., "Treatment of tear trough deformity and lower lid bowing with injectable hyaluronic acid" 29 : 363-367, 2005

6 Goldberg RA, "Treatment of lower eyelid retraction by expansion of the lower eyelid with hyaluronic acid gel" 23 : 343-348, 2007

7 Seiff SR., "The fat pearl graft in ophthalmic plastic surgery: everyone wants to be a donor!" 21 : 105-109, 2002

8 Colemans SR, "The anatomy of the aging face: volume loss and changes in 3-dimensional topography" 26 (26): 4-9, 2006

9 Flowers RS, "Tear trough implants for correction of tear trough deformity" 20 : 403-415, 1993

10 Kornstein AN, "Soft-tissue reconstruction of the brow with restylane" 116 : 2017-2020, 2005

11 Biesman B, "Soft tissue augmentation using restylane" 20 : 171-177, 2004

12 Friedman PM, "Safety data of injectable non animal stabilized hyaluronic acid gel for soft tissue Dugmentation" 28 : 491-494, 2002

13 Ciuci PM, "Rejuvenation of the periorbital complex with autologous fat transfer: current therapy" 66 : 1686-1693, 2008

14 John HE, "Perspectives in the selection of hyaluronic acid fillers for facial wrinkles and aging skin" 3 : 225-230, 2009

15 Ross JJ, "Orbitofacial rejuvenation of temporal hollowing with perlane injectable filler" 30 : 428-433, 2010

16 Fezza JP, "Nonsurgical treatment of cicatricial ectropion with hyaluronic acid filler" 121 : 1009-1014, 2008

17 Taban M, "Nonsurgical management of congenital eyelid malpositions using hyaluronic acid gel" 25 : 259-263, 2009

18 Airan LE, "Nonsurgical lower eyelid lift" 116 : 1785-1792, 2005

19 Lowe NJ, "Hyaluronic acid skin fillers: adverse reactions and skin testing" 45 : 930-933, 2001

20 Zamani M, "Functional use of hyaluronic acid gel in lower eyelid retraction" 126 : 1157-1159, 2008

21 Goldberg RA, "Filling the periorbital hollows with hyaluronic acid gel: initial experience with 244 injections" 22 : 335-341, 2006

22 Steinsapir KD, "Deep-fill hyaluronic acid for the temporary treatment of the naso-jugal groove: a report of 303 consecutive treatments" 22 : 344-348, 2006

23 Schanz S, "Arterial embolization caused by injection of hyaluronic acid (Restylane)" 146 : 928-929, 2002

24 Zimbler MS, "Anatomy and pathophysiology of facial aging" 9 : 179-187, 2001

25 Lowe NJ, "Adverse reactions to dermal fillers: review" 31 : 1616-1625, 2005

26 DeLorenzi C, "A multicenter study of the efficacy and safety of subcutaneous nonanimal stabilized hyaluronic acid in aesthetic facial contouring: interim report" 32 : 205-211, 2006