한국인 집단의 분자유전학적 연구 - 12. 한국인 집단에서의 혈장내 응고인자 FXIIIA , FXIIIB 및 보체 C1R 의 유전적 다형 = Molecular Genetic Studies of Korean Population - 12. Genetic Polymorphism of Coagulation Factor XIII A and B Subunit , and Complement Subcomponent C1R of Plasma in Korean Population

다국어 초록 (Multilingual Abstract)

As a part of research for clarifying the genetic polymorphism and composition of Korean population, the investigators have studied the phenotypes and allele frequencies of FXIIIA, FXIIIB and CIR in the plasma of Korean were analysed by agarose gel and polyacryiamide gel isoelectric focusing followed by immunoblotting. The allele frequencies of FXIIIA*1 and FXIIIB*2 and FXIIIB*3 were calculated to G1R*1 and G1R*2 were 0.663 and 0.337. The frequency of FXIIIA*1 was similar between Blacks and Whites, while that of Koreans and Japanese were slightly higher. However, the frequency of FXIIIB*3 in Whites was slightly higher than in Blacks, but that in Korean people was much higher than them. And the frequency of G1R*1 in Koreans was significantly lower than in Blacks and in Whites.