한국인 광회춘술(Photo-Rejuvenation)에 있어 2세대 IPL의 530∼750 nm와 555∼950 nm Waveband의 효용성 및 안정성에 대한 비교 연구 = A Comparative Study of the Efficacy and Safety of 530∼750 nm and 555∼950 nm Wavelength Bands of 2nd Generation IPL in Korean Photo-Rejuvenation한국인 광회춘술(Photo-Rejuvenation)에 있어 2세대 IPL의 530∼750 nm와 555∼950 nm Waveband의 효용성 및 안정성에 대한 비교 연구

다국어 초록 (Multilingual Abstract)

Background: Recently, the 2nd generation IPL with a filtered xenon flash lamp has been widely used in the dermatologic field. In disagreement with the manufacturer`s intent, for Asian skin, there were some reports that the best results for vascular lesions were obtained with the PR applicator, while the best results for pigmented lesions were obtained with the VL applicator. Objective: The purpose of this study is to compare the efficacy and safety of two different (530∼750 nm PR applicator and the 555∼950 nm VL applicator) wavelength bands of 2nd generation IPL in Korean photo-rejuvenation. In addition, we compared the improvement of telangiectasia, irregular pigmentation, and overall patient` satisfaction for both settings. Methods: Twenty-two patients with signs of photoaging skin including irregular pigmentation and telangiectasia were treated with 2nd generation IPL (Ellipse-Flex(R), DDD, Denmark) using a split-face comparative method, comparing both sides with respect to improvement of telangiectasia, irregular pigmentation, and overall patient satisfaction. Results: Comparison of the efficacy and safety between the VL and PR applicators revealed that the VL applicator was not specific for vascular lesions and that the PR applicator was not specific for pigmented lesions. Additionally, VL is not better than PR for vascular lesions (p=0.80, McNemar test) and PR is not better than VL for pigmented lesions (p=0.80, McNemar test). Finally, improvements in skin texture were not significantly different between VL and PR (p=0.80, McNemar test). Conclusion: The two IPL wavelength bands were found to be effective in the treatment of photo-damaged facial skin. The difference between the two treatment procedures with regard to clinical efficacy and safety was not significant. (Korean J Dermatol 2009;47(2):140∼147)

참고문헌 (Reference)

1 임선미, "혈관성 병변에 대한 Intense Pulsed Light의 치료효과" 대한피부과학회 43 (43): 218-224, 2005

2 이양원, "표피 멜라닌 세포성 병변에 대한 Intense Pulsed Light의 치료효과" 대한피부과학회 42 (42): 145-150, 2004

3 Weiss RA, "Treatment of poikiloderma of Civatte with an intense pulsed light source" 26 : 823-828, 2000

4 Alaluf S, "The impact of epidermal melanin on objective measurements of human skin colour" 15 : 119-126, 2002

5 Suzuki H, "Safety and efficacy of a secondgeneration intense pulsed source for treating Asian skin. Abstract" 36 : 75-75, 2005

6 Bitter PH, "Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments" 26 : 835-842, 2000

7 Bjerring P, "Intense pulsed light source for treatment of facial telangiectasias" 3 : 169-173, 2001

8 Hernandez-Perez E, "Intense pulsed light in the treatment of striae distensae" 28 : 1124-1130, 2002

9 Goldman MP, "Intense pulsed light as a nonablative approach to photoaging" 31 : 1179-1187, 2005

10 Ross EV, "Intense pulsed light and laser treatment of facial telangiectasias and dyspigmentation: some theoretical and practical comparisons" 1188-1198, 2005

11 서동해, "Intense Pulsed Light Quantum SR™을 이용한 안면부 피부노화에 대한 치료 3례" 대한피부과학회 42 (42): 1019-1023, 2004

12 Kollias N, "In vitro and in vivo ultraviolet-induced alterations of oxy- and deoxyhemoglobin" 56 : 223-227, 1992

13 Clementoni MT, "Facial telangiectasias: our experience in treatment with IPL" 37 : 9-13, 2005

14 Bjerring P, "Facial photo rejuvenation using two different intense pulsed light (IPL) wavelength bands" 34 : 120-126, 2004

15 Prieto VG, "Effects of intense pulsed light on sun-damaged human skin, routine, and ultrastructural analysis" 30 : 82-85, 2002